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Analysis of Case II drug transport with radial and axial release from cylinders

Citation:

Kosmidis K, Rinaki E, Argyrakis P, Macheras P. Analysis of Case II drug transport with radial and axial release from cylinders. INTERNATIONAL JOURNAL OF PHARMACEUTICS. 2003;254:183-188.

Abstract:

Analysis is presented for Case II drug transport with axial and radial release from cylinders. The previously reported {[}J. Control Release 5 (1987) 37] relationships for radial release from films and slabs are special cases of the general solution derived in this study. The widely used exponential relation M-t/M-infinity = kt(n) describes nicely the first 60% of the fractional release curve when Case II drug transport with axial and radial release from cylinders is operating. (C) 2003 Elsevier Science B.V. All rights reserved.