The attainment of adult status in Greece is a neglected research issue. Sociodemographic changes and the severity and long duration of the global financial crisis in this country (2008–2018) may have contributed to the delayed entry into adulthood, especially among university students. In this study, conducted during the financial crisis (2015), 814 university students (ages 18–25; M = 19.9) provided information on subjective adult status, subjective adult status with significant others, achievement of adulthood criteria, and several personal and contextual variables. Results showed that two thirds of the sample felt in-between adolescence and adulthood, thus supporting the existence of the emerging adulthood period. They felt more adult in work, university, and romantic relationships, and less adult with parents, friends, and siblings. The criteria achieved most were in the areas of Norm Compliance and Independence, whereas Role Transitions had been achieved the least. A variety of achievements, reflected in Independence, Norm Compliance, and Family Capacities criteria, and some concrete transitions were significantly associated with subjective adult status. Age, gender, parents' educational level, financial constraints, and financial concerns significantly and differentially predicted the achievement of several adulthood markers. Results provide insight into the attainment of adult status in a specific cohort of Greek youth during the aftermath of the Global Recession and underline the need for continuing research on the transition to adulthood in more recent cohorts of youth in this cultural context.

Complex-frequency excitations have recently attracted a lot of attention owing to their ability to solve a number of extraordinary challenges in photonics, such as overcoming losses without gain in metalenses and plasmonic waveguides and achieving virtual absorption. However, the totality of the works so far has been mainly computational or experimental, and a full theory of the complex dynamics enabled by these excitations is still missing. Here, we develop a fully analytical, exact time-domain theory for the dynamical scattering of these excitations by both sides of dielectric plates, which have been used to achieve virtual absorption. Our precise theoretical analysis confirms previous observations and, in addition, reveals a number of intriguing phenomena that were previously missed, such as discontinuities in the scattering of the outgoing electromagnetic field and release of the stored energy in distinct packets.

The Arctic region, one of the most vulnerable areas globally, faces severe climate change impacts, with rising sea levels and temperatures threatening local communities. Modern geoinformation tools provide a reliable, cost-efficient, and time-saving method for assessing these climate changes in Arctic coastal regions. This study focuses on Finland’s Arctic and sub-Arctic diverse coastline. The Coastal Vulnerability Index (CVI) is used to assess the vulnerability of Finland’s coastlines, using advanced geoinformatics tools. Integrating high-resolution data from EMODnet, the National Land Survey of Finland Digital Elevation Model (DEM), and physical sources, the CVI includes six input parameters: geomorphology, coastal slope, shoreline change rates, mean wave height, tidal range, and relative sea-level change. The CVI results reveal pronounced spatial variability: 37% of the coastline is classified with very low vulnerability, primarily in the southern Gulf of Finland, and some northern segments, specifically part of Lapland, exhibit minimal susceptibility to coastal hazards. Conversely, the central Gulf of Bothnia shows high vulnerability (29%), with low and moderate vulnerability zones comprising 27% and 6%, respectively, and very high vulnerability at 1%. This assessment provides essential insights for sustainable coastal management in Finland by offering a replicable model for Arctic coastal assessments. This study supports policymakers and local communities in developing targeted adaptation strategies to enhance resilience against climate-driven coastal hazards.

Mitochondrial dysfunction is a shared hallmark of neurodegenerative disorders, including Alzheimer's disease (AD) and tauopathies among others. Pathological alterations of the microtubule-associated protein Tau can disrupt mitochondrial dynamics, transport, and function, ultimately leading to neuronal toxicity and synaptic deficits. Understanding these processes is crucial for developing therapeutic interventions. The nematode Caenorhabditis elegans serves as a powerful model to study mitochondrial morphology and Tau-induced neurotoxicity due to its well-characterized nervous system and genetic tractability. Here, we describe a robust methodology for assessing mitochondrial morphology, Tau aggregation, and neuronal integrity in a nematode model of tauopathy. By combining confocal laser scanning microscopy and motility assays, we provide a comprehensive framework for investigating mitochondrial deficits. This approach offers valuable insights into the interplay between Tau pathology and mitochondrial dysfunction, thereby advancing our understanding of neurodegenerative mechanisms and potential therapeutic targets.

Geoethics, which addresses the ethical, social, and cultural dimensions of geoscientific activities, is essential for fostering responsible human engagement with the Earth, particularly within frameworks such as UNESCO Global Geoparks (UGGps). UGGps play a critical role in safeguarding geological heritage and advancing sustainable regional development. This study introduces the Geoethical Awareness Scale (GAS), a 32-item instrument developed across 16 thematic axes, designed to assess geoethical awareness. We analyzed responses from n = 798 residents across nine Hellenic UGGps using Exploratory and Confirmatory Factor Analyses, retaining items with factor loadings of ±0.30 or higher. Six factors emerged: (1) geological heritage conservation and sustainable georesource use, (2) community engagement and collaborative governance, (3) sustainability through geoenvironmental education, (4) environmental challenges and risk adaptation, (5) sustainable geotourism, and (6) climate awareness and ecosystem resilience. Collectively, these factors explained 60.12% of the variance, with Cronbach’s alpha values demonstrating acceptable to excellent reliability. Structural Equation Modeling confirmed the scale’s validity, with fit indices indicating acceptable model adequacy. Incremental indices suggested moderate alignment, while parsimony-adjusted metrics supported a balance between model complexity and fit. Overall, the GAS demonstrated generalizability and sufficient sample robustness. Correlation analyses highlighted the role of geoeducation, organizational involvement, and direct experience in fostering pro-geoconservation attitudes. While perceptions of sustainable development and ecosystem resilience varied geographically across UGGps, community engagement and governance remained consistent, likely reflecting standardized policy frameworks. GAS offers a valuable tool for assessing geoethical awareness and underscores the importance of targeted geoeducation and participatory governance in promoting ethical geoscientific practices within UGGps and similar socioecological systems.

BACKGROUND: Nodal assessment in gallbladder cancer remains challenging, particularly in incidental gallbladder cancer. This understages the number of patients with node-positive disease, resulting in prognostic inaccuracy and insufficient adjuvant treatment. This study aimed to identify risk factors for positive nodes in gallbladder cancer and to compare prognostic discrimination of available nodal staging parameters. METHODS: This international cohort study assessed gallbladder cancer resections undertaken between 1 January 2010 and 31 December 2020. Logistic regression was used to identify risk factors for node-positive status and develop a risk prediction score for positive nodes. Nodal staging models, including nodal site, number of positive nodes, and positive node ratio were compared for greatest prognostic discrimination in gallbladder cancer. RESULTS: A total of 3676 patients underwent gallbladder cancer resection across 133 centres in 41 countries. Tumour (T) stage (T2, P = 0.012; T3, P = 0.002; and T4, P < 0.001), lymphovascular and perineural infiltration (P < 0.001), and tumour differentiation (P < 0.001) carried the greatest risk of positive nodes. These three parameters comprised the OMEGA Node Positivity Prediction Score (OMEGA-NOPPS) with C-statistics of 0.81 (95% confidence interval 0.78 to 0.84) in the training data set and 0.79 (0.73 to 0.85) in the test data set for identification of node-positive status, highlighting a ≥ 20% increased risk of positive nodes in poorly differentiated tumours with lymphovascular and perineural infiltration despite T1 disease. CONCLUSION: Data from this large multicentre study confirmed that the number of positive nodes is the most discriminative prognostic model for nodal staging in gallbladder cancer. OMEGA-NOPPS provides three simple parameters to stratify nodal involvement according to risk. Incidental gallbladder cancer with lymphovascular and perineural infiltration and poorly differentiated tumours, including early T stages, should be considered for further treatment.

Athens Demapped. Archaeology, Heritage, and Urban Transformation explores the entangled relationships between classical heritage, memory, and modernity in the evolving city of Athens. Dimitris Plantzos interrogates how archaeology, tourism, and urban planning have shaped the city's identity, revealing Athens not as a timeless monument to antiquity but as a contested landscape where past and present collide.Rather than a neutral cultural asset, Athens’ classical legacy has been mapped, commodified, and weaponised – used both to forge collective memory and to marginalise dissenting voices. Plantzos critically engages with nostalgia, gentrification, and the politics of heritage, exposing how the myth of Athens as the “cradle of Western civilisation” continues to serve shifting ideological and economic agendas.At the heart of the book is the concept of “demapping”: the erasure or overwriting of certain spaces, histories, and communities to reinforce dominant narratives and commercial interests. Drawing on archaeological insight, urban theory, and cultural critique, Athens Demapped reimagines the city as a site of overlapping histories and contested futures.At a moment of rapid urban transformation, this book offers a vital perspective on the uses of the past and the right to the city. Essential reading for scholars of heritage, politics, and space.

Processing of sensory stimuli generated by our own actions differs from that of externally generated stimuli. However, most evidence regarding this phenomenon concerns the processing of unisensory stimuli. A few studies have explored the effect of self-generated actions on multisensory stimuli and how it affects the integration of these stimuli. Most of them used abstract stimuli (e.g., flashes, beeps) rather than more natural ones such as sensations that are commonly correlated with actions that we perform in our everyday lives such as speech. In the current study, we explored the effect of self-generated action on the process of multisensory integration (MSI) during speech. We used a novel paradigm where participants were either listening to the echo of their own speech, while watching a video of themselves producing the same speech (“talk”, active condition), or they listened to their previously recorded speech and watched the prerecorded video of themselves producing the same speech (“listen”, passive condition). In both conditions, different stimulus onset asynchronies were introduced between the auditory and visual streams and participants were asked to perform simultaneity judgments. Using these judgments, we determined temporal binding windows (TBW) of integration for each participant and condition. We found that the TBW was significantly smaller in the active as compared to the passive condition indicating more accurate MSI. These results support the conclusion that sensory perception is modulated by self-generated action at the multisensory in addition to the unisensory level.

We perform a theoretical investigation of the electron–surface optical phonon (SOP) interaction in Van der Waals heterostructures (vdWHs) formed by monolayer graphene (1LG) and transition metal dichalcogenides (TMDCs), using eigenenergies obtained from the tight-binding Hamiltonian for electrons. Our analysis reveals that the SOP interaction strength strongly depends on the specific TMDC material. TMDC layers generate localized SOP modes near the 1LG/TMDC interface, serving as effective scattering centers for graphene carriers through long-range Fröhlich coupling. This interaction leads to resonant coupling of electronic sub-levels with SOP, resulting in Rabi splitting of the electronon energy levels. We further explore the influence of different TMDCs, such as WS2, WSe2, MoS2, and MoSe2, on transport properties such as SOP-limited mobility, resistivity, conductivity, and scattering rates across various temperatures and charge carrier densities. Our analysis confirms that at elevated temperatures and low carrier densities, surface optical phonon scattering becomes a dominant factor in determining resistivity. Additionally, we investigate the Auger recombination process at the 1LG/TMDC interface, showing that both Auger and SOP scattering rates increase significantly at room temperature and higher, ultimately converging to constant values as the temperature rises. In contrast, their impact is minimal at lower temperatures. These results highlight the potential of 1LG/TMDC-based vdWHs for controlling key processes, such as SOP interactions and Auger recombination, paving the way for high-performance nanoelectronic and optoelectronic devices.

This two-wave study aimed to adapt the Basic Psychological Needs Satisfaction and Frustration Scale (BPNSFS) to the Turkish language and cultural context. At Time 1, participants included 1033 Turkish high school students (Mage = 15.91, SD = 0.36; 41.9% female) from 26 public schools located in Ankara, Türkiye. At Time 2, 849 students continued to participate in the study. A series of CFA provided support to the originally proposed six-factor solution of the BPNSFS and its time invariance along a 6-month period. The results also revealed that in addition to the six-factor model, the Multi-Trait, Multi-Method (MTMM) model could also be used in future research. In addition, testing the reliability and validity of the scale, regression analyses showed that satisfaction of the three needs positively predicted life satisfaction and negatively predicted depressive feelings, while an opposite trend was observed for the need frustration. Our findings suggest that the Turkish version of the scale is reliable and carries similar psychometric features to the original version. © 2025 Wiley Periodicals LLC.

Heterojunction formation between BiVO4 nanomaterials and benchmark semiconductor photocatalysts has been keenly pursued as a promising approach to improve charge transport and charge separation via interfacial electron transfer for the photoelectrocatalytic degradation of recalcitrant pharmaceutical pollutants. In this work, a heterostructured TiO2/Mo-BiVO4 bilayer photoanode was fabricated by the deposition of a mesoporous TiO2 overlayer using the benchmark P25 titania catalyst on top of Mo-doped BiVO4 inverse opal films as the supporting layer, which intrinsically absorbs visible light below 490 nm, while offering improved charge transport. A porous P25/Mo-BiVO4 bilayer structure was produced from the densification of the inverse opal underlayer after post-thermal annealing, which was evaluated on photocurrent generation in aqueous electrolyte and the photoelectrocatalytic degradation of the refractory anti-inflammatory drug ibuprofen under back-side illumination by visible and UV–Vis light. Significantly enhanced photoelectrochemical performance on both photocurrent density and pharmaceutical degradation was achieved for the bilayer structure with respect to the additive effect of the constituent layers, which was related to the improved light harvesting arising from the backscattering by the mesoporous TiO2 layer in combination with the favorable charge transfer at the TiO2/Mo-BiVO4 interface.

Can sport act as a mediator between cultures? Can sport serve as a tool for social inclusion? Is the social space of sport providing the means for moving from integration to inclusion? Are team sports and physical activity facilitating refugee and migrant integration, to wit providing migrants, refugees and asylum seekers with a form of support in regaining and maintaining their mental health and well-being?  This paper argues that the social space of sport offers a platform, a bridge and a stage—for vulnerable social groups—to promote social integration and subsequently inclusion. In sharing personal stories about refugees and displaced communities, athletes have been challenging stereotypes and encouraging their social media followers to adopt more inclusive attitudes. This paper examines grassroots programs and projects involving tens of thousands of participants around the globe from educators, visionaries, volunteers, and diverse stakeholders, who are using sport to promote social inclusion. Moreover, a wide variety of organizations have been using the power of play and games to nurture peacemaking across divided communities; to ensure visibility; to promote intercultural awareness and gender equality; to eliminate racism and violence in schools and communities. Policy makers claim sport contributes to a wide range of ideals such as intercultural understanding, reconciliation, and integration. In Greece, for example, the Ministry of Labor and Social Affairs includes sport, as a tool to promote social justice, in the current National Action Plan for Gender Equality (NAPGE). Remarkable results have been documented in bridging social inequality gaps through sport. Keywords: sport agency, athlete activism, visibility, integration, inclusion, gender, refugee, migrant, xenophobia  

A new giant outburst of the Be X-ray binary RX J0520.5-6932 was detected and subsequently observed with several space-borne and ground-based instruments. This study presents a comprehensive analysis of the optical and X-ray data, focusing on the spectral and timing characteristics of selected X-ray observations. A joint fit of spectra from simultaneous observations performed by the X-ray telescope (XRT) on the Neil Gehrels Swift Observatory (Swift) and Nuclear Spectroscopic Telescope ARray (NuSTAR) provides broad-band parameter constraints, including a cyclotron resonant scattering feature (CRSF) at $32.2_{-0.7}^{+0.8}$ keV with no significant energy change since 2014, and a weaker Fe line. Independent spectral analyses of observations by the Lobster Eye Imager for Astronomy, Einstein Probe (EP), Swift-XRT, and NuSTAR demonstrate the consistency of parameters across different bands. Luminosity variations during the current outburst were tracked. The light curve of the Optical Gravitational Lensing Experiment (OGLE) aligns with the X-ray data in both 2014 and 2024. Spin evolution over 10 yr is studied after adding Fermi Gamma-ray Burst Monitor data, improving the orbital parameters, with an estimated orbital period of 24.39 d, slightly differing from OGLE data. Despite intrinsic spin-up during outbursts, a spin-down of $\sim$0.04 s over 10.3 yr is suggested. For the new outburst, the pulse profiles indicate a complicated energy-dependent shape, with decreases around 15 and 25 keV in the pulsed fraction, a first for an extragalactic source. Phase-resolved NuSTAR data indicate variations in parameters such as flux, photon index, and CRSF energy with rotation phase.

As global life expectancy continues to rise, the need to understand and mitigate the effects of aging on human physiology has become increasingly important. Aging is characterized by cellular and functional decline, resulting in a higher prevalence of chronic diseases. Model organisms, such as Caenorhabditis elegans, provide valuable insights into the molecular mechanisms underlying aging and serve as platforms for developing potential therapeutic interventions. This chapter highlights the utility of C. elegans in aging research by presenting three straightforward protocols: the lifespan assay, thrashing assay, and lipofuscin accumulation assay. These assays are designed to effectively assess key physiological aspects of organismal health and provide a reliable framework for monitoring the aging process and evaluating anti-aging compounds. Here, we demonstrate the application of these protocols using Urolithin A as an example, underscoring their efficacy in advancing our understanding of aging and contributing to the development of potential interventions.

Calcium signaling plays a pivotal role in diverse cellular processes through precise spatiotemporal regulation and interaction with effector proteins across distinct subcellular compartments. Mitochondria, in particular, act as central hubs for calcium buffering, orchestrating energy production, redox balance and apoptotic signaling, among others. While controlled mitochondrial calcium uptake supports ATP synthesis and metabolic regulation, excessive accumulation can trigger oxidative stress, mitochondrial membrane permeabilization, and cell death. Emerging findings underscore the intricate interplay between calcium homeostasis and mitophagy, a selective type of autophagy for mitochondria elimination. Although the literature is still emerging, this review delves into the bidirectional relationship between calcium signaling and mitophagy pathways, providing compelling mechanistic insights. Furthermore, we discuss how disruptions in calcium homeostasis impair mitophagy, contributing to mitochondrial dysfunction and the pathogenesis of common neurodegenerative diseases.

The anticipated rise in extreme flood events in the Eastern Mediterranean region indicates an increase in significant societal impacts that have the potential to extend beyond the flooded areas and affect multiple sectors. Despite the criticality of understanding storm and flood risk and how they propagate in modern interconnected societies, the scope and complexity of storm- and flood-triggered cascading effects are still poorly comprehended. This study explores the effects created by the extreme Storm Daniel, occurring in Thessaly, Greece in 2023, aiming to gather new evidence on the types and scale of these cascading effects by analyzing its impacts in the region through fieldwork and official data collection. The results, as a contribution to existing knowledge on cascade effects, provide insights into the nature, the extent, the propagation mechanisms, and the consequences of these triggering events leading to diverse cascade effects. The study identifies the interactions between different phenomena following this extreme storm event to offer a better understanding of how impacts propagate, and therefore a better understanding of future challenges connected with this type of cascading hazards framework, ultimately contributing to predicting and mitigating associated risks.

The increasing frequency and severity of extreme storms and floods in the Eastern Mediterranean under climate change pose significant challenges for modern societies. These events often trigger cascading effects that extend far beyond the immediate disaster zone, disrupting interconnected systems such as power, transportation, and communication networks. Despite advancements in flood risk management and growing awareness of cascading hazards, the mechanisms driving these interdependencies and their broader impacts remain poorly understood. This study investigates the cascading effects triggered by the catastrophic Storm Daniel, which struck Thessaly, Greece, in September 2023, as a case study to explore the nature, scale, and ways of impact propagation.This work also provides an analysis of cascading effects, based on evidence on historical storm and flood disaster impacts in the Mediterranean region, identifying the interactions between primary hazards (flooding, landslides, erosion) and secondary consequences as well as the diverse sectors that suffer impacts. The analysis reveals different propagation mechanisms of these effects, highlighting the vulnerability of interconnected systems as well as the vulnerability of the natural and the built environment. The cascading effects identified underscore systemic risks of modern societies posed by extreme events, particularly in urban areas with dense, interdependent, and critical infrastructure.The findings contribute to the growing body of literature on cascading disasters, addressing critical knowledge gaps in understanding how extreme weather events propagate through modern societal systems. These insights are particularly relevant in the context of climate change, which is expected to amplify the frequency and intensity of such events.

People living in prisons have higher mortality rates compared to the general population. We undertook a retrospective analysis of deaths recorded between 2010 and 2018 at the sole prison hospital in Greece (Korydallos Prison Special Health Centre for men) to assess the causes of death overall and by type of offence (drug-related or other), sociodemographic characteristics by cause of death, and mortality trends over time. Permission to access forensic reports and criminal files was obtained from the relevant authorities. Deaths were categorized as either non-natural (drug overdose, suicide, and homicide) or natural (cardiovascular disease, cancer, and others). Between 2010 and 2018, 236 deaths were reported; 80.9% were natural deaths, and 19.1% were non-natural deaths. The primary causes of death were circulatory disease (34.7%), cancer (17.8%), suicide (10.2%), respiratory disease (8.9%), and overdose (6.4%). Suicide and overdose accounted for 53.3% and 33.3% of non-natural deaths, respectively. The mean (SD) age at death was 52.4 (16.2) years, with individuals experiencing non-natural deaths being significantly younger than those experiencing natural deaths [39.1 (10.5) vs. 55.5 (15.7), p < 0.001]. Among individuals incarcerated for drug-related offences, 23.8% died from non-natural causes, with drug overdose accounting for 60% of non-natural deaths. A significant peak in mortality was observed in 2013. This study emphasizes the need to closely monitor mortality rates, including drug-related fatalities, to implement suicide prevention training as well as measures to prevent deaths by overdose, including comprehensive harm reduction strategies, overdose education, and naloxone training.

A small, strongly schistose Ni-laterite occurrence at the Vermion ophiolite (40°26′ Ν, 22°10′ Ε), Northen Greece, along a strong shear zone, is characterized by relatively high Ni, Co and Mn contents, magnetite as the dominant mineral, garnet (grossularite), theophrastite [β-Ni(OH)2], otwayite-like phase (ideally Ni2CO3(OH)2.H2O), (Ni, Co, Mn)-hydroxides, and Ni-phyllosilicates. New analytical data, including black-white and color back-scattered electron images (BSEIs), elemental mapping and scanning, and Raman Spectroscopy, alongside silicates and hydroxides revealed the presence of varying silica content (less than 1 to 29 wt.%) in theophrastite and in (Ni, Co, Mn ± Fe)-hydroxides, although the X-ray powder diffraction data correspond to those of pure hydroxides. The gradual stacking of fine fibrous otwayite-like crystals to the boundaries of successive thin layers and within layers themselves, results in porous mineral phases of varying density shifting towards more compact mineral with increasing residence time. The presented data suggest that a potential explanation of the presence of Si in theophrastite may be the precipitation of Si after initial Ni-hydroxyl-carbonate fine crystals deposition. A potential sequence of the stability of Ni-minerals at Vermion may be as follows: Hydroxyl-carbonates < [β-Ni(OH)2] (theophrastite) < (Ni, Co, Mn)(OH)2 < Ni-phyllosilicates; this may be a significant factor for Ni-exploration in Ni-larerite deposits.

Τhe idea that social influences and social interactions play a central role on individual economic decisions has had a long presence in the history of economics. With the emergence of marginalism, this idea went into background and the concept of atomistic individual became established in mainstream economic rationality. Starting in the 1970’s, there were some attempts to reintroduce non-atomistic preferences in mainstream microeconomic theory in the form of social interactions, interdependent preferences, keeping up with the Joneses, social identity, social preferences, and status concerns. Social preferences have started to have a growing impact among mainstream microeconomics with the advent of behavioral economics, but still they are not in the hard core of the standard theory of choice. The paper argues that atomistic preferences are still prevalent, especially in the form of the assumption of representative agent. It also focuses on the role of methodological individualism and on the theoretical implications of relaxing the assumption of atomistic individual, as main explanations of the resilience of the mainstream economic rationality.

BACKGROUND AND OBJECTIVES:Traumatic brain injury (TBI) is a major public health challenge in India but there is a lack of high-quality data on its clinical characteristics and outcomes. We aimed to describe the TBI population of a tertiary care center in India, identify predictors of inpatient mortality, and assess the performance of existing prognostic tools.METHODS:We conducted a prospective observational cohort study of patients admitted to a high-volume tertiary care center in Vellore, India, after a TBI between 2013 and 2019.RESULTS:

INTRODUCTION: Quality of life measures from the patient's subjective experience are important, since it capture how the treatment affects their daily life, functional abilities, and emotional well-being. This study aimed to measure patients' QoL prior and after Transcatheter Aortic Valve Implantation (TAVI) procedure. METHODS: This prospective study was conducted from November 2022 to December 2024 in a sample of 302 TAVI patients from three public Hospitals in Greece. Patients were recruited and followed up at the point of discharge and six months after discharge. Patient-reported quality of life was recorded using both the generic EQ-5D-5L and KCCQ a disease-specific HRQoL instrument. Descriptive statistical analysis was performed using SPSSv.29. RESULTS: The results of the study indicate excellent clinical outcomes with low mortality rates and low incidence of severe complications. Improvements in TAVI techniques and patient selection have led to decreased mortality rates. Six months follow-up confirms the great clinical outcome, and readmission rates were limited to two cases. From the patients' perspective, the overall outcome was rated as acceptable or favourable by most of them, with movement problems and pain being commonly stated. After discharge, the patients stated better outcomes both regarding their daily living, mobility and psychological state, reporting less stress and depression. CONCLUSION: QoL assessments help determine the true benefit of TAVI beyond just survival rates. Further research is needed to stress the main determinants of QoL in these patients and to guide the everyday clinical practice.

It is often inferred that rising sea levels will result in widespread coastal recession. Erosion appeared prevalent in a worldwide compilation of evidence derived from maps and aerial photographs undertaken in the 1980s by the Commission on the Coastal Environment. Eric Bird, chair of the commission, inferred that >70% of sandy coastlines had retreated, a generalisation that has been widely cited. We reconsider these findings in respect of subsequent advances in shoreline mapping, including greater precision possible using geographical information systems and more frequent remote sensing imagery with increased spatial, spectral and temporal resolution. Satellite-derived shorelines now enable broad global and regional generalisations about shoreline position. Beaches fluctuate over a range of timescales, meaning that trends in their position are highly dependent on techniques and temporal scales adopted for monitoring. Recent global- and regional-scale shoreline assessments indicate that many sandy shorelines have been stable, and that detectable retreat has occurred on fewer beaches than previously inferred. Accretion is apparent on some coasts, particularly where engineering interventions protect or have reclaimed land. There is considerable variability in the behaviour of monitored beaches, and it is not yet possible to decipher a response to the gradual centimetre-scale rise in sea level of recent decades. Instead, we re-emphasise the several other factors that were considered to contribute to recession by the Commission, many of which relate to a change in sediment budget. To provide insights into future coastline behaviour, a better understanding of the multiple drivers on individual beaches is needed to discriminate between erosional events and longer-term trends in shoreline position.

Telehealth holds the potential to expand healthcare access for people who use drugs (PWUD). However, limited data exist on their digital infrastructure access, a prerequisite for telehealth participation. We studied digital healthcare accessibility among PWUD.

ABSTRACT The Lake Volvi area, part of the region of Macedonia (northern Greece), is a biodiversity hotspot, located in the central part of a major communication corridor connecting the western and eastern parts of the Balkans. The sediment succession from Lake Volvi is investigated here to provide a unique high-resolution pollen and geochemical record for the last 2000 years combining palaeoecological and historical methods, implementing the concept of consilience. The palaeoecological data document the environmental dynamics since the occupation of the area by the Romans. The vegetation changes reveal the development of wetland habitats and the variations of the mixed deciduous oak and thermophilous?mesophilous forests, as well as cereal cultivation, grazing and arboriculture, whose intensity varied over time. Archaeological data are available for the 1st millennium ce, but detailed historical evidence becomes accessible from the 13th century  ce onwards through Byzantine and Ottoman documents. Both historical and palaeoecological data indicate that the 16th century was the period of strongest population pressure on the environment of the Volvi region. However, for other periods, it is possible to observe disagreements between the proxies. We demonstrate that these contradictions can be resolved with a more complex understanding of the region's social?ecological dynamics.

Obesity is an important risk factor for atrial fibrillation (AF) development. Data on cryoballoon ablation (CBA) outcomes in obese patients have so far been scarce. We reviewed the existing literature to compare the efficacy and safety of CBA in obese versus non-obese AF patients. A systematic literature search was conducted for studies comparing clinical outcomes (arrhythmia recurrence and/or procedural data and/or safety outcomes) between obese and non-obese patients undergoing CBA for AF. Statistical pooling was performed according to a random-effects model with generic inverse-variance weighting of relative risks (RRs) and standardised mean differences (SMDs) computing risk estimates with 95% confidence intervals (CIs). Obese and non-obese patients had comparable arrhythmia recurrence rates (normal versus overweight, RR = 0.95, 95% CI: 0.82-1.11, = 0.55, I% = 91%; normal versus class I obesity, RR = 0.97, 95% CI: 0.82-1.13, = 0.68, I% = 87%; normal versus class II obesity, RR = 0.98, 95% CI: 0.91-1.07, = 0.29, I% = 65%). Procedure time was marginally increased in obese patients compared to non-obese counterparts (normal versus overweight, SMD = 0.05, 95% CI: -0.15-0.26, = 0.62, I% = 74%; normal versus class I obesity, SMD = 0.10, 95% CI: -0.00-0.19, = 0.06, I% = 2%; overweight versus class I obesity, SMD = 0.11, 95% CI: 0.01-0.21, = 0.048, I% = 25%). Regarding radiation exposure, fluoroscopy time was increased in patients with class I obesity compared to normal-weight or overweight patients and dose area product was also increased in obese patients compared to non-obese patients. Lastly, the risk of complications did not differ between obese and non-obese patients. Statistical heterogeneity and the small number of patients included are the main limitations of this study. CBA seems to be effective for obese patients suffering from AF, featuring also similar safety outcomes with non-obese individuals. Radiation exposure was increased in obese patients.

The weights and structure determination (WASD) neuronet (or neural network) is a single-hidden-layer feedforward neuronet that exhibits an excellent approximation ability, despite its simple structure. Thanks to its strong generalization, fast speed, and ease of implementation, the WASD neuronet has been the subject of many modifications, including metaheuristics, and applications in a wide range of scientific fields. As it has garnered significant attention in the last decade, the aim of this study is to provide an extensive overview of the WASD framework. Furthermore, the WASD has been effectively used in numerous real-time learning tasks like regression, multiclass classification, and binary classification due to its exceptional performance. In addition, we present WASD’s applications in social science, business, engineering, economics, and medicine. We aim to report these developments and provide some avenues for further research.

Intensifying climate change impacts, such as Sea-Level Rise (SLR), floods, extreme weather events and coastal erosion, threaten ecosystems, infrastructure, and human communities at a global scale, making vulnerability assessments a crucial prerequisite for identifying areas necessitating urgent and effective actions. The Coastal Vulnerability Index (CVI) is a widely used index-based methodology for such assessments; yet its implementation often relies on complex, manual workflows across multiple proprietary desktop Geographic Information Systems (GIS) software. Existing approaches limit accessibility, lack transparency, hinder reproducibility, and are frequently time-consuming. To address these challenges, CVIc (Coastal Vulnerability Index Compiler) is presented herein as a novel, open-source, and open-access geoprocessing web application for the computation of the CVI. CVIc provides an end-to-end dynamic workflow, guiding users from shoreline data import to the application of various standardized indices (CVI, ICVI). CVIc is deployed as a website (https://alexandrosliaskos.github.io/CVIc/) and features interactive tools for shoreline digitization, segmentation, parameter value assignment, and visualization and export of results. The only input requirements are a shoreline Shapefile input or a GeoTIFF image for digitization, and the knowledge of the spatial distribution of the parameter values for the area under study. By leveraging IndexedDB for browser-based data storage, CVIc operates without server-side dependencies, ensuring data privacy, protection and large-scale dataset processing. To our knowledge, this consists the first web solution of its kind, as its streamlined approach into a unified and user-friendly platform makes this type of analysis more feasible to researchers and coastal practitioners, while providing policymakers with more accessible and robust data for decision-making. Its open-source nature enables community-driven advancements, and the simple User Interface (UI) and map components mark it as appropriate for educational purposes.

A base-catalyzed protocol is reported for the construction of 1,3-thiazolidine-2-thione scaffolds bearing quaternary carbon centers from carbon disulfide and α-tertiary propargylamines. The reaction proceeds using low catalyst loading, under ambient temperatures, and in the absence of solvent. Various α-tertiary propargylamines have been employed, affording a series of previously unreported thiazolidine-2-thione compounds and avoiding purification via column chromatography in certain cases. We also describe a one-pot strategy for the synthesis of the same products through a KA2 coupling-CS2 incorporation approach. The reaction mechanism and substituent-dependent catalytic behavior were studied through a combination of detailed experimental and computational studies.

Despite Greece’s historical and geographical significance in the Mediterranean, there is currently no national digital repository offering systematic access to Arabic chronicles, diplomatic letters, and travelogues from the eighth to sixteenth centuries. This absence critically impedes rigorous Arabological and Islamological research within Greek academia and restricts the educational landscape to predominantly Eurocentric perspectives. The Hellenic Digital Library of Arabic Historical Sources (HDB-AHS) is proposed as a pre-implementation targeted solution, presenting a trilingual (Greek–English–Arabic) digital platform designed to aggregate, preserve, and openly disseminate these vital sources. The article outlines a six-phase implementation plan combining IIIF, TEI-XML, FAIR for interoperability and reuse and CARE principles where community authority or sensitivity requires it, and open licensing with a robust rights–clearance framework for modern copyrights and sensitive materials. Beyond academic benefits, the project aspires to act as a meeting point of cultures, offering concrete tools for building bridges, combating intolerance, and fostering intercultural understanding. In a world that is rapidly changing, the creation of such an inclusive and responsibly curated digital resource is vital not only for advancing research but also for supporting dialogue and mutual respect across societies. The HDB-AHS provides a blueprint for similar initiatives in underrepresented fields.

The standard wave equation describing symmetrical wave propagation in all directions in three dimensions, was discovered by the French scientist d’Alembert, more than 250 years ago. In the 20th century it became important to search for ‘one-way’ versions of this equation in three dimensions– i.e., an equation describing wave propagation in one direction for all angles, and forbiting it in the opposite direction– for a variety of applications in compu tational and topological physics. Here, by borrowing techniques from relati vistic quantum field theory– in particular, from the Dirac equation–,and starting from Engquist and Majda’s seminal, approximative one-way wave equations, we report the discovery of theexactone-waywaveequationin three dimensions. Surprisingly, we find that this equation necessarily– simi larly to the innate emergence of spin in the Dirac equation– has a topological nature, giving rise to strong, spin-orbit coupling and locking, and non vanishing (integer) Chern numbers.

Saccadic eye movement tasks have been widely used as a probe for measuring cognitive functions in healthy humans as well as in patients with neurological and psychiatric disorders. Circadian variation has been shown to affect multiple aspects of cognitive function especially executive function related to prefrontal cortex. The effects of diurnal variation in saccadic task performance and the dissociation of these effects from repetition or practice effects has not been adequately addressed. In the current study thirty healthy adults performed several saccadic eye movement tasks including visually guided saccades, antisaccades and countermanding saccades in three consecutive sessions. Participants were divided into three groups, with a different starting time of the sequence of the three sessions across groups (morning or afternoon or evening) to examine the effect of diurnal variation (time of day that the tasks were performed) separated from the effect of session repetition (practice effect). The results showed no effect of diurnal variation for all indexes of saccadic eye movement performance including accuracy (antisaccade and countermanding saccade tasks) speed (mean latency in all tasks) and stability (intra-subject standard deviation of latency in all tasks). In contrast, saccadic task repetition significantly improved accuracy, speed and stability of performance indicating the presence of practice effects in these tasks. Finally, linear mixed model analysis confirmed no interaction between diurnal variation and practice effects for all indexes of saccadic eye movement performance. In conclusion our study provides confirmation that saccadic task performance is not affected by diurnal variation related to circadian rhythms. In contrast, short term repetition of these tasks results in significant practice effects.

This study attempts to provide insight into the origins of aloneness and loneliness by comparatively and jointly examining the views of psychoanalysts and researchers Margaret Mahler and Daniel Stern. Their influential theories combine the developmental and the clinical perspective and have the potential to offer a deeper understanding of these universal and fundamental experiences. First, Mahler’s and Stern’s views on aloneness and loneliness are organized and presented in detail. Reformulations and critiques are also reported. Next, the two models are examined in relation to each other regarding the issues of aloneness and loneliness. Points of convergence and divergence are identified and discussed. These points revolve around the following issues: the onset of aloneness and loneliness experiences; the nature and developmental trajectories of aloneness and loneliness; the interpersonal context within which this development takes place; the ability to cope with loneliness and the factors that facilitate or hinder the development of this ability; and the related psychopathological pathways with their clinical implications.

In his 1994 novel The Waterworks, E. L. Doctorow constructs a modernGothic tale of horror in the heart of New York City at the end of the nineteenthcentury. Adopting Slavoj Žižek’s “parallax view,” this article contends thatDr. Sartorius’s gory, antagonistic obsession to defeat death constructs a nightmarishnetwork of undead spectral “life” that escapes the ontological horizondelineated by the Symbolic and, at the same time, disrupts its social inscription,rendering visible fin de siècle societal antagonisms. The undead non-subjectswhose materialization is contingent upon the blood and bone marrow of the childrenupon which they prey are used in this modern Gothic text as an exemplificationof the unspeakable Real that is inscribed into the very fabric of capitalism.

The experiences of the Balkan peoples are common, as reflected in the folk songs of their countries. The purpose of this study is to present the common cultural elements and moral social codes of the Greeks and Serbs, as they were shaped in the historical context of the time and are evident in the folk songs "The dead brother" and "The daughter and her brothers" (Браћа и Сестра/lat. Braća i Sestra). In more detail, this comparative study presents similarities in the lives of Greeks and Serbs, in terms of the institution of the family, family ties, the marriage custom, the social status of women, the common experience of being abroad, but also other issues, such as belief in the change of fortune, belief in the power of the oath, and the treatment of death. Finally, a brief reference is made to the common theme of the above songs with similar folk songs from other Balkan countries, which demonstrates the common beliefs and perceptions of the people of the region.

Background/Objectives: Acute low back pain (LBP) is a prevalent cause of disabilityworldwide. If often involves both inflammation and reflex muscle spasm, suggestingcombined therapy with a non-steroidal anti-inflammatory drug (NSAID) and a musclerelaxant may provide superior relief. This study aimed to evaluate the short-term efficacy and safety of a single intramuscular (IM) injection of a fixed-dose combination (FDC) product containing Diclofenac and Thiocolchicoside versus Diclofenac monotherapy in adults with acute LBP. Methods: We conducted a phase III multicenter, randomized, double-blind, parallel-group trial in 140 patients with acute LBP of moderate to severe intensity. Patients were allocated 1:1 to receive either the combination of Diclofenac sodium 75 mg + Thiocolchicoside 4 mg (FDC product, Test Group) or Diclofenac sodium 75 mg alone (Diclofenac monotherapy, Reference Group) via a single IM injection. The primaryoutcome was the change in patient-reported pain intensity using the Visual Analogue Scale(VAS) from baseline to 3 h post-dose. Key secondary outcomes included pain change at1 h in the VAS, improvement in lumbar mobility (finger-to-floor distance test, FTF), theproportion of patients achieving >30% pain reduction, and the incidence of adverse events(AEs). Randomization was centralized and both investigators and patients were blindedto the treatment. Results: All 140 randomized patients completed the trial. At 3 h postinjection,the combination therapy produced a significantly greater mean pain reductionthan monotherapy (41.52 mm vs. 28.13 mm on the 100 mm VAS; p < 0.0001). Superiority of the combination was already evident at 1 h post-dose (VAS reduction 27.61 mm vs. 20.40 mm; p = 0.0089). Lumbar flexion improved more with the combination at 3 h (mean FTF distance improvement 14.52 cm vs. 7.94 cm; p < 0.0001) and at 1 h (9.21 cm vs. 4.62 cm;

The paper discusses the Hellenistic necropoleis of Alexandria in Egypt: the tombs, the finds, the paintings, Greco-Egyptian ideas on death and dying. We will be exploring Macedonian responses to death and dying, as well as the ways Macedonian mortuary habits were transmitted, transposed, developed and “edited”, once the Macedonians found themselves on top of the world, and in lands so different from their own. From Macedon to Asia and Egypt, and from Aigai and Mieza to Shatby, Macedonians had to renegotiate their fundamental beliefs on death and the afterlife, committing themselves to the amalgam we now understand as “Ptolemaic Alexandria”.

BACKGROUND: Electrical storm (ES) is a life- threatening condition. Both recurrence and mortality rates remain unacceptably high. Current guidelines recommend initial conservative approach using anti-arrhythmic drugs (AADs), followed by catheter ablation (CA) for those with refractory ES. METHODS: We searched PubMed and Scopus for articles comparing an initial conservative approach - based on AADs/ sedation- with an early referral for CA approach. The primary endpoint was long term mortality, while secondary endpoints included ES recurrence and the incidence of ventricular arrhythmias (VAs)/ defibrillator shocks during the follow- up. RESULTS: Seven studies, primarily observational cohorts, were analyzed. The pooled population (999 patients) consisted mostly of males with ischemic cardiomyopathy, presenting with ventricular tachycardias (VTs). The mean left ventricular ejection fraction was 35.5 % (9.5 %). 493 patients were treated with CA during the index hospitalization. Early CA was associated with significantly lower long- term mortality (OR: 0.44, 95 %CI: 0.31-0.63). Additionally, it was associated with lower rates of both ES recurrence and VAs/ shocks during the follow- up (OR: 0.27, 95 %CI: 0.15-0.48 and OR: 0.33, 95 %CI: 0.21-0.52, respectively). CONCLUSIONS: Meta- analysis of primarily observational studies revealed that early referral of ES patients for CA may improve their prognosis. The invasive approach was associated with lower mortality and reduced recurrence rates of major arrhythmic events. Although some inherent limitations affect the strength of these findings, they remain promising. They highlight the need for further research on the topic, as their confirmation in randomized trials could lead to a shift in the standard of care of ES patients.

In the early months of 2025, a significant seismic activity was recorded in the area between Santorini and Amorgos, raising concerns about the potential occurrence of a major earthquake and a possible tsunami. The objective of this study is to assess the earthquake-triggered tsunami hazard in the Santorini-Amorgos Tectonic Zone (SATZ) by simulating tsunami processes using the MOST (Method of Splitting Tsunami) numerical model, implemented through the ComMIT (Community Model Interface for Tsunamis). High-resolution bathymetry and topography were employed to model tsunami generation, propagation, and onshore inundation. A total of 60 simulations were conducted using a deterministic approach based on worst-case scenarios. The analysis considered six major active faults with two kinematic types, pure normal and oblique-slip, and assessed tsunami impact on five selected coastal study areas. The simulations results showed potential maximum run-up values of 4.1 m in Gialos (Ios), 2.7 m in Kamari (Santorini), 2.4 m in Perissa (Santorini), 1.5 m in Katapola (Amorgos), and 2.3 m in Chora (Astypalaea), in some cases affecting residential zones. Inundation flows also impacted the main ports of Gialos, Katapola, and Chora, highlighting the exposure of critical infrastructure. Although earthquake-triggered tsunamis represent a potential hazard in the SATZ, the results indicated that it is unlikely to cause a widespread disaster in the study areas.

Occasioned by Hans Klein’s commentary, this study examines the history of interpretation of Rom 7:25b by comparing Protestant and Orthodox exegetical traditions. Klein, following Augustine and Luther, sees the verse as describing the believer’s ongoing internal struggle (simul iustus et peccator). In contrast, Greek patristic exegetes assign the “divided self” to the unredeemed human, while highlighting the baptized believer’s ability to overcome sin. The article suggests that although both traditions partly diverge from Paul’s theological view, they can complement one another when not taken in an absolute sense. The study concludes with a pastoral caveat regarding the mindset of believers: while the Protestant perspective may lead to resignation and despair over sin, the Orthodox emphasis on spiritual perfection may foster neurotic dissonance and self-estrangement. A hermeneutical approach is proposed to help navigate everyday spiritual struggle, growth, and the path to sanctification.

Je fais partie de ceux qui aiment la vie. J’ai eu le bonheur d’avoir de bons parents, de fonder une famille heureuse... Toute ma vie, j’ai travaillé à des tâches passionnantes : j’ai aimé mes études, j’ai fait avec joie de l’enseignement et de la recherche... Je ne cesse de m’intéresser à la vie du monde, à la promotion de la femme, au maintien de la paix. Je fais confiance aux possibilités de l’homme et je crois au progrès. Je ne demande qu’à travailler, c’est-à-dire à vivre jusqu’à l’extinction de mes forces. Ces mots d’Eugénie Cotton disent tout : la passion de vivre, l’élan d’agir, la volonté de transmettre. Son itinéraire de vie singulier embrasse deux siècles et trois Républiques, traverse deux grandes guerres, connaît l’âge d’or puis l’effondrement d’un Empire colonial. Femme de science, elle s’imposa au début du XXe siècle dans un monde d’hommes. Femme de tête sous le Front populaire, elle réforma l’École normale supérieure de jeunes filles. Militante infatigable, elle devint, en pleine guerre froide, l’une des dirigeantes internationales du mouvement féminin et pacifiste, inscrivant ainsi son engagement dans un espace de luttes sociales, politiques et féministes. Autant d’histoires d’une vie et d’un siècle racontées à la manière d’une passionnante enquête.

This book offers the first comprehensive history and analysis of Turkey’s relations with Israel since 1948, when the state of Israel was established, up until 2010 and places them within the wider framework of Turkey’s foreign policy. It highlights the remarkable lack of consistency in Turkey’s foreign policy towards Israel, under different Turkish governments, which has given the relationship a pervasive sense of unpredictability.  Combining empirical-analytical evidence with role theory insights, as developed in Foreign Policy Analysis (FPA), it explores Turkish foreign policy makers’ perceptions regarding the proper role and function of the country in the international system and the sub-system of the Middle East and how they affected the policy towards Israel. The author argues that Ankara’s ambivalent policy towards Israel for over sixty years can be explained by Turkey's multiple and often contradictory national role conceptions. The study, which draws from archival material and over fifty interviews with Turkish, Israeli, American and Arab officials and experts, places Ankara’s policy into a larger analytical framework, which helps link the past to the present and future.

Η ιδέα για μία νέα καταγραφή δημοτικών τραγουδιών του Δυτικού Παγγαίου ήταν ένα από τα πολλά ευχάριστα παράπλευρα οφέλη του 2ου Συνεδρίου Τοπικής Ιστορίας που διοργανώθηκε στην Ελευθερούπολη από τον Δήμο Παγγαίου και την Ιερά Μητρόπολη Ελευθερουπόλεως τον Οκτώβριο του 2018. Αποτέλεσε τον κοινό τόπο στον οποίο συναντήθηκαν ο Ιωάννης Κιορίδης, συμμετέχων στο εν λόγω συνέδριο, με τους υπευθύνους του Λαογραφικού Μουσείου Πρώτης “Χαγιάτι Λαδιά”, Βασιλική Λαδιά και Χρήστο Τσιφούτη. Βασική ιδέα του παρόντος εγχειρήματος είναι η συγκέντρωση των δημοτικών τραγουδιών που η Βασιλική Λαδιά και ο Χρήστος Τσιφούτης κατέγραψαν και ενίοτε ηχογράφησαν σε βάθος αρκετών ετών και μέχρι πρόσφατα (τέλη 2023). Τα τραγούδια αυτά τραγουδήθηκαν κυρίως στην Πρώτη και σε ορισμένα άλλα μικρότερα χωριά του Δυτικού Παγγαίου. Άλλα απαντούν μόνο σε αυτές τις περιοχές και άλλα σε πλήθος παραλλαγών ανά την Ελλάδα. Στην παρούσα συλλογή περιλαμβάνονται 142 από αυτά τα τραγούδια.

This is the first translation into Greek with an introduction, commentary, and appendix of the Song of Roncesvalles, a 13th-century text concerning the actions of Charlemagne and Roland in Iberia

The leadership style employed by those in positions with authority could significantly impact employees' work behavior, either positively or negatively. : The aim of the study was to examine the impact of engaging leadership on quiet quitting and work engagement among nurses. A cross-sectional study was conducted in Greece with a convenience sample. Data collection occurred throughout October 2024 via an online survey. We utilized Google forms to create an online version of the study questionnaire, which was subsequently shared in Facebook groups for nurses. We used validated tools to measure our study variables, namely, the "Engaging Leadership Scale-12" for engaging leadership, the "Quiet Quitting Scale" for quiet quitting, and the "Utrecht Work Engagement Scale-3" for work engagement. We applied univariate and multivariable linear regression analyses to identify the association between engaging leadership, quiet quitting, and work engagement. -values less than 0.05 were considered statistically significant. Our multivariable models showed a negative association between engaging leadership and quiet quitting. Moreover, we found a positive association between engaging leadership and work engagement after the elimination of confounders. : Our findings suggest that higher levels of engaging leadership reduce quiet quitting and improve work engagement. Nurses' managers should adopt engaging leadership to improve nurses' motivation and, thus, clinical outcomes.

In early 2024, the largest full-scale exercise (FSE) for earthquakes and related geohazards in Greece was implemented in Crete Island (southern Greece). Crete is characterized by intense seismicity with historical and recent destructive earthquakes with considerable impact on both the natural and built environment and subsequently on the population. The uniqueness of this FSE lies in the creation and coordination of a multi-agency, multijurisdictional, and multidisciplinary environment in which a multitude of central, regional, and local stakeholders and a large percentage of the total population of Crete actively participated. This paper constitutes a descriptive study focusing on the main steps of the exercise management cycle comprising planning, implementation, and evaluation of the FSE. Furthermore, emphasis is given on its purpose and objectives, its main events and subsequent incidents, the participants and their roles, as well as the material developed and distributed to the participants. Through this study, the implemented actions for increasing preparedness of the Civil Protection mechanism in case of earthquakes and related geohazards are highlighted aiming to inform the scientific community and operational staff and to contribute to the seismic risk reduction of regions worldwide with similar seismotectonic and demographic characteristics with Crete. Furthermore, suggestions are made for the integration of multi-hazard episodes in the FSE scenario in order that the Civil Protection authorities will be prepared to handle the synergy of hazards of different types that may arise during a post-earthquake period that create compounding challenges during the emergency response and further increase recovery time.

The impact of metal contacts on the electrical properties of SiN dielectric film in MEMS capacitors is investigated. The investigation is performed employing MIM and MEMS capacitors with Au and Ni contacts. A resistive switching like behaviour is monitored in the case of Ni contacts. This behaviour is attributed to the presence of deep traps in SiN and the effect of different metal contacts as revealed from Thermally Stimulated Depolarization Current (TSDC) assessment. Specifically, TSDC showed that the resistive switching is a contact/interface dominated effect.

Loneliness represents a negative feeling that arises when individuals perceive a discrepancybetween actual and desired social relationships. The present study explored the meanings andpersonal experiences of loneliness in children and early adolescents in Italy. Participants included139 children and early adolescents aged 8–14 years (M = 10.76 years, SD = 1.71; 80 girls, 57.6%)who completed a semi-structured interview online. Different dimensions emerged from the codingprocess, providing evidence of the multidimensional nature of loneliness, defined and experiencedthrough different dimensions (e.g., cognitive, emotional, and regarding interpersonal context).Results from descriptive analyses (i.e., frequencies and percentages) showed that most of theparticipants defined loneliness in terms of physical separation from others. Also, participantsdiscussed loneliness in relation to both their family and peers. Some children and adolescentsexpressed experiencing loneliness voluntarily. Children and early adolescents reported to feelsadness, anger and other emotions as boredom, happiness, and fear in associations with loneliness.Finally, we examined gender and grade differences between the dimensions with a series of chisquaretests and ANOVAs. Results revealed that primary school children and boys defined andexperienced loneliness using the physical separation dimension. Middle school children definedloneliness using the cognitive dimension more frequently. Overall, the present study offers a richerunderstanding of the meanings and experiences of loneliness in youth and highlights the importanceof considering developmental, gender, and cultural factors when studying loneliness.

The orchestration of dynamic epigenetic and epitranscriptomic modifications is pivotal for the fine-tuning of gene expression. However, these modifications are traditionally examined independently. Recent compelling studies have disclosed an interesting communication and interplay between m6A RNA methylation (m6A epitranscriptome) and epigenetic modifications, enabling the formation of feedback circuits and cooperative networks. Intriguingly, the interaction between m6A and DNA methylation machinery, coupled with the crosstalk between m6A RNA and histone modifications shape the transcriptional profile and translational efficiency. Moreover, m6A modifications interact also with non-coding RNAs, modulating their stability, abundance, and regulatory functions. In the light of these findings, m6A imprinting acts as a versatile checkpoint, linking epigenetic and epitranscriptomic layers toward a multilayer and time-dependent control of gene expression and cellular homeostasis. The scope of the present review is to decipher the m6A-coordinated circuits with DNA imprinting, chromatin architecture, and non-coding RNAs networks in normal physiology and carcinogenesis. Ultimately, we summarize the development of innovative CRISPR-dCas engineering platforms fused with m6A catalytic components (m6A writers or erasers) to achieve transcript-specific editing of m6A epitranscriptomes that can create new insights in modern RNA therapeutics.

Brain organoids are in vitro 3D cultures generated in the lab from human induced pluripotent stem cells or embryonic stem cells and can mimic the human brain structure and function. Specifically, they reproduce to some extent in vivo developmental events as they consist of diverse cell types, such as apical radial glial cells, intermediate progenitors, basal radial glial cells, and neurons forming stratified cortical layers similar to what is observed in the human brain in vivo. Due to cytoarchitecture similarities between the human brain and brain organoids, the latter have been proposed as excellent models for studying human brain development and disease. Thus, genome manipulation in brain organoids is crucial for investigating the functions of specific genes and mutations that have been associated with brain-related disorders. For this reason, gene manipulation has been implemented in brain organoids in the last few years. Here, we describe a step-by-step protocol for gene expression manipulation and analyses in brain organoids via acute electroporation that we have optimized based on the in vivo electroporation that has been widely used in animal models. This easy-to-apply protocol is fast and robust and facilitates the precise spatiotemporal manipulation of the expression of any gene of interest.

Tinos Island, part of the Cyclades Complex in the central Aegean Sea, represents a distinctive case of geocultural heritage where geological formations and cultural identity intersect. This study evaluates the geoeducational and geotouristic potential of Tinos’ geosites using GEOAM methodology, which assesses their scientific, educational, and conservation value. Six geosites are examined to explore their geoeducational potential, including prominent locations such as the Tafoni formations and the Exombourgo granite massif. The findings highlight the significance of these sites, while also identifying challenges related to infrastructure, stakeholder engagement, and sustainable management. By integrating geoethics into geotourism practices, Tinos can adopt a balanced approach that enhances environmental conservation alongside community-driven economic benefits. The study underscores the need for collaborative initiatives to optimize the island’s geoheritage for education and tourism, ensuring its long-term preservation. Geotourism, when responsibly implemented, has the potential to strengthen local identity while advancing sustainable tourism development.

The study presents a geomorphological overview of Greece at a 1:1,000,000 scale, marking the first national cartographic synthesis effort to interpret geological and geomorphological factors shaping the country's landscape. The geomorphological map was developed through a literature review of prior studies at varying scales and semi-automated GIS techniques. High-resolution topographic data and 1:50,000 geological maps were integrated into a spatial geodatabase. Secondary layers, including a hillshade map, slope-aspect map, and red relief image map, were created and combined with Google Earth imagery to delineate landforms. These were categorized by primary formative processes into structural, fluvial, gravity-induced, coastal, karst, volcanic, glacial and periglacial. Additional maps and tables were produced, detailing topographic parameters, geotectonic setting, and climatic regime. The results highlight Greece's diverse geomorphological environments, shaped by active tectonics and surface processes. The map represents recent geomorphological advancements and serves as a management tool for stakeholders and a reference for interdisciplinary research.

The present study investigates the formation and development of a coastal barrier associated with the recent evolution of the beach/dune system of the Kyparissiakos Gulf (SE Ionian Sea, central Mediterranean Sea) during the late phase of the Holocene (Flandrian) transgression. The study is based on the application of combined geophysical (ERT: Electrical Resistivity Tomography; GPR: Ground Penetrating Radar) and geotechnical (CPT: Cone Penetration Test; boreholes) techniques, supported by sedimentological (granulometric, mineralogical, palaeontological) analyses. According to the interpretation of the collected and processed data, the formation of the coastal barrier started during the transition between the fast and slow phase of the sea level rise (i.e. 6-7 ka BP), which coincides with an increased fluvial sediment inflow induced by the prevailing wetter climatic conditions (8000 - 3700 BP). The development of the coastal barrier most likely involves a progradational beach, associated with the formation of dunes that follow aggradational phases of coastal barrier and beach evolution. Based on 14C dating, the formation of the two younger dune ridges took place no earlier than 350 and 950 cal yr BP, respectively.

Der aktuellste Text des griechischen Neuen Testaments mit einem leicht zugänglichen textkritischen Apparat. Nach über zehn Jahren intensiver Vorbereitung erscheint jetzt eine Neuauflage des UBS Greek New Testament (6. Auflage).  Sie bietet den aktuellsten griechischen Text mit den Textänderungen der Bände der Editio Critica Maior zur Apostelgeschichte (2017), dem Markusevangelium (2021) und der Offenbarung (2025). So unterscheidet sich der Text an weit über 100 Stellen vom Text der 5. Auflage.  Der Text ist identisch mit dem der 29. Auflage des Novum Testamentum Graece ("Nestle-Aland"), die für 2026 in Vorbereitung ist.  Der Apparat umfasst klar strukturierte Einträge zu allen wichtigen Varianten des Textes. Bei der Auswahl der Stellen war die Frage nach der Relevanz für Übersetzung und Auslegung des Textes leitend. Auch die Bedeutung des sog. Textus Receptus wurde gegenüber früheren Auflagen verstärkt berücksichtigt. Die Auswahl der Handschriften wurde gegenüber der 5. Auflage zum einen auf die wichtigsten Zeugen fokussiert, zum andern durch neue Handschriften (Papyri 128 bis 141) ergänzt. Eine gut lesbare Einführung (auf Englisch) führt zu der Ausgabe hin.  Insgesamt ist dieses Werk dadurch besser als je geeignet für den Einstieg in die exegetische und textkritische Arbeit am Neuen Testament in seiner Originalsprache.  Es wird von einem internationalen und interkonfessionellen Gremium herausgegeben, das auch für NA29 verantwortlich ist und eng mit dem Institut für Neutestamentliche Textforschung zusammenarbeitet: Hugh Houghton, Christos Karakolis, David Parker, Stephen Pisano, Holger Strutwolf, David Trobisch und Klaus Wachtel. 

Flash floods have been responsible for some of the most catastrophic events globally. The extensive range of effects and the varying severity of impacts present significant challenges in accurately understanding the damage caused by a flood event, thereby hindering our capacity to predict future consequences. When evaluating flood impacts and their severity, most existing approaches rely on qualitative descriptions (e.g., major, catastrophic, etc.) or examine the impacts from a single perspective or discipline, such as economic losses. In this study, the Flash Flood Impact Severity Scale (FFISS) is employed to evaluate, map, and categorize the impacts of two flash floods that occurred in the Lilas River in Greece in 2009 and 2020. The goal of this application is to analyze the varying severity levels and how one flood event can influence the impacts of a subsequent event. The methodology involved extensive fieldwork, including the collection of ground-based and aerial observations using UAV technology to document the impacts. These observations were subsequently georeferenced, followed by applying the Flash Flood Impact Severity Scale (FFISS) and creating detailed maps to assess and evaluate the severity of impacts associated with the two flood events. The results indicate that, despite the higher water levels during the second flood, areas previously affected show lower severity values. This reduction is attributed to the community’s gradual adaptation, improvements in infrastructure, and significant local widening of the river channel. Conversely, newly flooded areas during the second event exhibit high severity levels. Overall, applying the FFISS reveals spatial patterns of impact severity, offering insights into the local nature of floods while suggesting a potential reduction in overall risk during the post-flood period.

This special issue of the journal Neusis focuses on the role of prediction in scientific practice and examines the following questions: How has the role and status of prediction changed historically? How is the gap between theory and prediction of specific phenomena bridged? What is considered a valid and successful prediction in different areas of the natural sciences?

Cellular senescence, a state of permanent cell cycle arrest, recapitulates the aging process at the cellular level. It can be triggered by intrinsic or extrinsic factors including telomere shortening (replicative senescence) and in response to various types of stresses such as oncogenic stress (oncogene-induced senescence, OIS). Senescence has been detected in vitro and in premalignant lesions in mice and humans expressing mutant oncogenes. MicroRNAs (miRNAs) are short noncoding RNAs that regulate gene expression at the posttranscriptional level, and have been involved in both replicative senescence and OIS. Several methods have been used to identify miRNAs and compare their expression in normal versus oncogene-induced senescent cells, as well as to analyze their role and their targets in senescence. Here, we describe several methods that can be employed to identify miRNAs in cells undergoing OIS, including miRNA-sequencing, RT-qPCR-based detection and quantification of miRNAs and Nanostring miRNA analysis (nCounter miRNA Expression Assay). Moreover, we perform a meta-analysis of studies employing the above methodologies, pinpoint miRNAs with consistent expression changes across senescence models, and predict their target genes and the pathways in which they partake.

(1) Background: The present study examines the effects of fire on the ecosystem services of forest ecosystems in Greece. Being a Mediterranean country, Greece has been affected by fires of increasing intensity and frequency in recent years; (2) Methods: Information was extracted from 56 articles published in the period January 1997–March 2024 that were selected after an extensive literature review; (3) Results: An increasing trend in the number of published articles over time was observed. Studies on regulating and maintenance services prevailed. The majority of studies reported on thermo-Mediterranean ecosystems, with Pinus halepensis Mill forests being the most common ecosystems affected by fires. The effects of fire were primarily negative on provisioning and cultural services, as well as on the control of erosion rates, regulation of the hydrologic cycle, atmospheric composition, and climate regulation. Most effects on plant diversity were found to be positive, while positive and neutral effects were also recorded for pollination. The most pronounced negative or positive effects were noted for the first two years after the fire. The spatial mapping of the results showed that the areas most affected by the fires in Greece are Eastern Attica, Euboea, Western Attica, and most regional units of the Peloponnese; (4) Conclusions: In the era of climate change and changing fire regimes in the Mediterranean, there is a need to further research the impact of fire on ecosystem services, as this will help in the better protection and management of the most vulnerable forest ecosystems.

The accurate representation of mixed-phase monsoon clouds and their phase distribution is of great importance for numerical models used to predict monsoon rainfall. Therefore, it is essential for these models to correctly capture the phase fraction of clouds, which includes the proportions of liquid and ice. Ice particle formation in clouds occurs through primary ice production and secondary ice production (SIP). Most weather and climate models tend to overlook secondary SIP mechanisms, often only including rime-splintering. This oversight can introduce biases in the phase partitioning of mixed-phase clouds and monsoon rainfall predictions. In this study, we investigate the roles of three major SIP mechanisms: Hallett-Mossop (HM), droplet shattering (DS), and ice-ice collision (IIC) in mixed-phase monsoon clouds. This investigation is the first of its kind and was conducted using high-resolution simulations of mixed-phase convective clouds observed during the fourth phase of the Cloud Aerosol Interaction and Precipitation Enhancement Experiment (CAIPEEX) over a rain shadow region of India. The default cloud microphysical scheme, which originally included only the HM process, was modified to incorporate additional SIP mechanisms such as DS and IIC. The simulated cloud parameters, including liquid and ice water content and ice number concentration, showed good agreement with airborne measurements. Our findings indicate that IIC is the predominant SIP mechanism, contributing 90 % to the total ice production through SIP. The inclusion of the three SIP mechanisms resulted in an enhancement of ice concentration by three to four orders of magnitude at temperatures warmer than -20 °C. SIP significantly influenced various cloud parameters between 0 to −20 °C, including total ice number concentration, ice crystal mass, rimed mass, liquid water content, and phase fraction. It also influenced the Ice Water Path (IWP), Liquid Water Path (LWP), and cloud top temperature. The rates of several mixed-phase processes were also affected by the SIP mechanisms. Overall, SIP led to a 15 % reduction in accumulated surface precipitation.

The present paper deals with the combined application of near-surface geophysical techniques in a sustainable agriculture project. Their application is focused on the identification of any subsurface water in the context of sustainable water management for the selected living hub, located in the semi-arid area of Agios Georgios-Mandra Attiki. The objective of the multidisciplinary geophysical study was to determine the depth of the bedrock and the thickness of the post-Alpine deposits. In addition, the subsurface karstification and the possible aquifer presence were examined. For that reason, the following techniques were implemented: Electrical Resistivity Tomography, Seismic Refraction Tomography, Ground-Penetrating Radar, and Very-Low Frequency electromagnetic technique. The study was also supported by drone LiDAR usage. The investigation revealed several hydrogeological characteristics of the area. The thickness of the post-Alpine sediments is almost 3 m. However, no shallow aquiferous systems have been developed in this formation, as indicated by their relatively high resistivity values (100–1000 Ohm.m). Furthermore, the alpine bedrock exhibits extensive karstification, facilitated by the development of fracture zones. The absence of an underlying impermeable layer prevented the development of aquiferous zones, at least up to a depth of 100 m.

Flash floods have been the cause of some of the most devastating events worldwide. The wide diversity of the effects, as well as the variety in the severity of the impacts, lead to major obstacles in obtaining a realistic understanding of the damages caused by a flood event, thus hampering at the same time our ability to predict future impacts. In assessing flood impacts and their severity, most existing methods use a qualitative characterization (e.g., major, catastrophic, etc.) or view the impacts from a single viewpoint or discipline (e.g., economic losses). In this study, we apply the Flash Flood Impact Severity Scale (FFISS) to assess, map, and classify the impacts of two flash floods from the Lilas River in Greece in 2009 and 2020. This application aims to discuss the different severity levels in terms of how one flood can affect the impacts of the next event. The methodology encompasses comprehensive field research, including the collection of ground-based and aerial observations utilizing UAV technology to document the impacts. These observations are subsequently georeferenced, followed by application of the Flash Flood Impact Severity Scale (FFISS) and generation of detailed maps to assess and evaluate the severity of the impacts associated with the two flood events. The results show that despite the higher water stage of the second flood, the impacts in previously hit areas indicate lower severity values, attributed to the gradual adaptation of the community and its infrastructure, as well as significant local widening of the river channel. On the contrary, high severity remains an issue in newly flooded areas during the second event. Overall, the application of the FFISS can show the spatial patterns of severity impacts, providing insights into the nature of floods locally but also indicating a potential reduction in the overall risk in the post-flood period.

Understanding the subsurface structural framework of mines is critical for ensuring operational safety. Especially in room and pillar marble quarries, where extraction strategies need continuous optimization and reorientation and since benching creates rooms with considerable heights, ensuring structural stability is crucial for the safety of personnel and equipment. This study presents a novel application of ground-based Li-DAR (Light Detection and Ranging) technology for high-resolution structural mapping within an active marble quarry. By deploying terrestrial laser scanning across key excavation galleries, we generated detailed 3D point clouds that reveal hidden discontinuities and fault systems with a non-invasive, rapid, and precise methodology, capable for representing de-tailed three-dimensional models of the quarry interiors. We used a Leica P50 scanner for acquiring point data in this marble quarry, covering an area of 8,800 m2. A volume of 46,900 m3 was mapped in high detail by setting up 9 bases, accompanied with the measurement of 12 ground control points (GCPs), which were utilized for the transform of al-most 960 million points into real coordinates.The resulting point cloud data were processed using ad-vanced geospatial software to generate 3D models and ex-tract structural features such as joints, faults, bedding planes, and correlate them with existing geological models, which were derived from classical surface mapping of outcrops. The analysis revealed several previously undocumented sub-surface structures that have direct implications for resource estimation, selection of support measures and operational planning. The high spatial resolution of LiDAR enabled the identification of subtle features that are typically missed by conventional surveying techniques.This study demonstrates that ground-based LiDAR is a pow-erful tool for subsurface structural mapping in marble quar-rying, offering significant advantages in terms of accuracy, safety, and efficiency.

The utilization of hybrid plasmonic metal/semiconductor materials for surface-enhanced Raman scattering (SERS) has emerged as a promising approach towards the development of advanced SERS substrates in terms of sensitivity{,} uniformity{,} stability{,} and reusability{,} based on the synergy of the powerful electromagnetic mechanism with the chemical amplification and functionality of semiconductor supports. In this work{,} co-assembled WO3/TiO2 inverse opal films were utilized as photonic crystal scaffolds of plasmonic Ag nanoparticles in order to optimally combine plasmonic{,} charge transfer and slow photon effects for ultrasensitive{,} recyclable SERS sensing. Compositional and photonic band gap engineering of the Ag-decorated WO3/TiO2 photonic crystal substrates provided insight to the interplay of plasmonic enhancement assisted by slow light propagation in the inverse opal structure and charge transfer between the analyte and the heterostructured substrate. Highly sensitive detection of 4-mercaptobenzoic acid as a non-resonant analyte was achieved down to 10−13 M for the optimal Ag–WO3/TiO2 substrate with good uniformity and excellent recyclability due to its enhanced photocatalytic self-cleaning capacity. Comparative performance tests along with photoelectrochemical evaluation showed a significant contribution of cascade electron transfer from plasmonic Ag to the staggered WO3/TiO2 heterojunctions and the analyte{,} providing an additional charge transfer pathway to promote the substrate-to-molecule interaction for the design of efficient and versatile metal/metal oxide SERS platforms.

The present paper deals with an inhabited, creeping mountainous landmass with profound surface deformation that affects the local community. The scope of the paper is to gather surficial and subsurface information in order to understand the parameters of this creeping mass, which is usually affected by several parameters, such as its geometry, subsurface water, and shear zone. Therefore, a combined aerial and surface investigation has been conducted. The aerial investigation involves UAV’s LiDAR acquisition for the terrain model and a comparison of historical aerial photographs for land use changes. The multi-technique surface investigation included resistivity (ERT) and seismic (SRT, MASW) measurements and density determination of geological formations. This combination of methods proved to be fruitful since several aspects of the landslide were clarified, such as water flow paths, the internal geological structure of the creeping mass, and its geometrical extent. The depth of the shear zone of the creeping mass is delineated at the first five to ten meters from the surface, especially from the difference in diachronic resistivity change.

This prospective study was conducted in four public tertiary hospitals in Greece. Consecutive cardiac patients (AMI or TAVI) (n=912) were registered and followed up at the point of discharge six months and 12 months after discharge. In case of AMI patients [N=610, mean age=63 (SD=11.8), 78.8% men, 48.8% STEMI], the Heart-QoL score was found 2.33 (SD=0.5) at the point of discharge, 2.61 (SD=0.31) six months after discharge and 2.68 (SD=0.3) twelve months after discharge. In case of TAVI patients [N=302, mean age=81 (SD=5), 50.7% men], the Heart-QoL score was found 1.54 (SD=0.38) at the point of discharge and 2.02 (SD=0.46) six months after discharge. Based on the results of the Danish Heart PREMs instrument (0-3), the majority of patients stated positive experiences during the cycle of care. However, positive experiences regarding the information they received about the psychosocial impact of cardiac issues on their lives (mean and organization (mean 1.03, SD =0.33 for AMI and 1.1, SD=0.35 for TAVI patients), were significantly limited. Results underline the necessity for in depth information of cardiac patients about the psychosocial effects of the disease on their lives and more effective coordination of healthcare.

An isotype heterojunction n+-ZnO/n-Si photodetector is developed, showing adjustable wavelength-selective operation at self-powered conditions. Without an external bias voltage, the device can operate either as a broadband ultraviolet-visible-near-infrared (UV-vis-NIR) or as a NIR-only photodetector. This is achieved by careful engineering of the relative carrier concentrations of the constituting materials, i.e., ZnO and silicon, which in turn affects the built-in potential barrier of the n+-n junction. In addition to this self-powered behavior, the photodetector can be tuned to either broadband or NIR operation by the application of an external bias voltage, regardless of carrier concentrations. At negative bias, it demonstrates UV-vis-NIR photodetection, while at positive bias, NIR photodetection for any ratio of ZnO/Si carrier concentrations investigated here.

Uncontrolled proliferation, resistance to apoptosis, inability to maintain genome integrity, and, recently, epigenetic reprogramming are all hallmarks of cancer. A number of gene expression and cell signaling networks control these-often-interconnected processes, while the study of their deregulation is in the forefront of cancer research for decades. Here we present data from cells and patients indicating that KMT2C, one of the most frequently mutated proteins in solid malignancies, is involved in all these processes. Its loss, a bad prognosis marker in bladder cancer, is associated with activation of the PI3K/PDK/AKT oncogenic/antiapoptotic axis, and tolerance to DNA damage during cell cycle progression. On the other hand, these cells suffer from mitotic stress that can be therapeutically exploited. Treatment with a PLK1 inhibitor showed high efficacy in vivo, and was associated with mitotic catastrophe and cellular senescence, providing evidence that targeting genes that promote mitotic progression could be a promising therapeutic approach in the subset of tumors with KMT2C loss.

RESUMENCon el objetivo de facilitar la labor de los docentes de ELE, nos proponemos indagarsobre la actividad ortográfica desde una perspectiva cognitiva, con el propósito decomprender los procesos mentales implicados y examinar si el nivel lingüístico enLE influye en dichos procesos. Para ello, se realizó un estudio con 142 aprendicesgriegos de ELE, clasificados en niveles lingüísticos (A, B y C). Estos participantesrealizaron una prueba de disponibilidad léxica, que permite acceder al proceso derecuperación de la forma ortográfica de las palabras más disponibles para ellos.Primero, se identificaron los errores ortográficos en las respuestas, tanto en laacentuación como en las letras. Posteriormente, se analizaron los datos desde unaperspectiva cuantitativa y cualitativa. El análisis cuantitativo indica que, alaumentar el nivel lingüístico, disminuye la cantidad de palabras con erroresortográficos. Sin embargo, los errores dentro de las palabras incorrectas semantienen constantes, lo que indica que las palabras con errores contienen másfallos internos. En relación con los errores de acentuación, estos persisten en todoslos niveles lingüísticos. El análisis cualitativo de los datos revela que muchoserrores de acentuación ocurren en palabras frecuentes y comunes que deberían serfáciles de escribir correctamente. En cuanto a los errores en las letras, estáninfluenciados por las otras LE que los aprendices conocen. Dichos resultadosrevelan que los participantes tienden a recuperar la forma ortográfica de laspalabras directamente a través de la vía léxica en lugar de seguir la vía fonológica.Estos hallazgos permiten proponer el tratamiento didáctico adecuado para lasdificultades ortográficas de los aprendices griegos de ELE.

Landslides represent a persistent hazard in Mediterranean en-vironments, necessitating reliable monitoring techniques for risk assessment. Recent advancements in 3D close-range re-mote sensing, particularly through the integration of Un-manned Aerial Systems (UAS) and Terrestrial Laser Scanning (TLS), have enhanced our ability to capture surface changes. Object-based analysis offers a robust framework for seg-menting and classifying landslide features from high-resolution spatial data, improving the detection and under-standing of landslide processes and rockfall dynamics be-yond traditional pixel-based methods. This work describes the use of repeated UAS and TLS surveys at several active landslide and rockfall sites, referring to the challenges that arose and the solutions that were provided. Point clouds were processed to generate high-resolution digital elevation models (DEMs), and object-based techniques were applied for sys-tematic segmentation and classification of landslide objects. Data fusion was performed following rigorous co-registration procedures, drawing on ground control points to align da-tasets from different sensors. Spatial and geomorphological attributes were extracted from classified objects for temporal change detection and feature analysis. UAS-derived models demonstrated efficient coverage and high surface detail, while TLS data provided increased point density and vertical accuracy in targeted sectors. Object-based analysis enabled the identification and delineation of distinct landslide fea-tures, such as scarps, displaced blocks, and accumulation zones, with improved accuracy compared to manual delinea-tion. The combined UAS-TLS approach reduced data gaps and enhanced the representativeness of classified objects. The segmentation process, however, was sensitive to vegeta-tion cover and point density variations, requiring parameter optimization for each dataset. Integrating advanced data analysis with fused UAS-TLS datasets improved the identifi-cation and monitoring of morphological changes, facilitating a more process-based understanding of landslide and rockfall dynamics. The object-based framework allowed for con-sistent feature extraction across temporal sequences, support-ing detailed change analysis and the recognition of geomor-phological evolution patterns. Challenges included managing data heterogeneity and ensuring segmentation reliability across varying surface conditions. This study demonstrates that combining object-based analysis with multi-sensor 3D data acquisition enhances landslide and rockfall feature de-tection and temporal analysis, providing a scientific basis for more effective landslide hazard assessment and management in Mediterranean terrains.

BACKGROUND: The aim of this study was to evaluate whether increased body mass index (BMI) and biochemical and lifestyle parameters linked to obesity and smoke exposure disrupt immune responses of children and adolescents following vaccination with the mRNA BNT162b2 vaccine. METHODS: A prospective, single-center, cohort study was conducted. Participants were assigned to receive two doses of the mRNA vaccine. Anti-SARS-CoV-2 IgG and neutralizing antibodies (AB) were measured before vaccination (T0) and 14 days after the second dose (T1). BMI and biochemical parameters were evaluated at T0. A questionnaire on lifestyle characteristics was filled in. RESULTS: IgG optical density (OD) ratio at T1 was lower in the overweight-obese group regardless of COVID-19 disease positive history [p = 0.028 for the seronegative group, p = 0.032 for the seropositive group]. Neutralizing AB were lower in overweight-obese participants in the seronegative group at T1 [p = 0.008]. HDL, fasting glucose/insulin ratio (FGIR), C-reactive protein (CRP), HBA1c, uric acid, and smoke exposure were significantly correlated with BMI [p = 0.006, p < 0.001, p < 0.001, p = 0.006, p = 0.009, p < 0.001, respectively]. The main biochemical parameters that were inversely correlated with IgG and neutralizing AB titers at T1 were uric acid [p = 0.018, p = 0.002], FGIR [p = 0.001, p = 0.008] and HBA1C [p = 0.027, p = 0.038], while smoke exposure negatively affected the humoral immune responses at T0 in the convalescent group [p = 0.004, p = 0.005]. CONCLUSIONS: Current data suggests that uric acid, insulin resistance (IR), and smoke exposure could adversely affect the immune responses in overweight-obese vaccinated children, highlighting the need for actions to enhance the protection of this particular subgroup.

This study explores the lived experiences of Greek emerging adults during the COVID-19 pandemic, focusing on perceived psychoemotional and social impacts and future outlooks. Using a qualitative longitudinal approach, we conducted two timeframes: March 2020 and June 2021, with thirty-four participants (M = 21.14 years old) initially responding to online open-ended questions, followed by in-depth interviews with six. Thematic analysis identified two main themes: ‘emotional shifts’ and ‘transitioning to adulthood’. Participants expressed a range of emotions, including sadness and nostalgia, leading to feelings of loneliness from being separated from loved ones. Throughout both timeframes, they reported fear and anxiety about contracting or spreading the virus. However, they also recognised positive changes during the first lockdown, such as personal growth and a deeper appreciation for life, which translated into ‘relational clearings’ during the second lockdown. Additionally, participants acknowledged their increased responsibility to comply with restrictions and formulated practical future plans reflecting a ‘here-and-now’ mindset. Our findings are discussed in relation to existing literature.

BACKGROUND: While long coronavirus disease 2019 (COVID-19) is linked to prolonged vascular dysfunction in adults, research in children remains poor. In this study, we assessed vascular health in children infected with severe acute respiratory syndrome coronavirus 2 about 6.8 months postinfection, comparing them with healthy controls. METHODS: Two hundred twenty-three children were assessed and divided into group 1, which included children with a positive disease history and group 2, which consisted of healthy controls. Anthropometric measurements, lipid profile, biomarkers (interleukin-6, C-reactive protein, tumor necrosis factor-alpha and soluble intracellular adhesion molecule) and long COVID symptoms were assessed, along with pulse wave velocity (PWV) measurements and carotid intima-media thickness (cIMT) to evaluate aortic stiffness. RESULTS: Children in group 1 were older (mean age: 10.8 +/- 3.2 years vs. 8.5 +/- 2.8 years, P < 0.001) and had higher body mass index (20.3 +/- 5.6 kg/m 2 vs. 18.4 +/- 3.5 kg/m 2 , P < 0.001). PWV was increased in group 1 (5.02 +/- 0.7 m/s vs. 4.7 +/- 0.6, P < 0.001). However, vascular differences between the groups disappeared after adjusting for age, body mass index, and blood pressure. Soluble intracellular adhesion molecule-1 levels were elevated in children with a history of moderate/severe COVID-19 infection compared with controls (555.8 +/- 113.2 ng/mL vs. 428 +/- 42.6 ng/mL, P < 0.001). Cholesterol levels, inflammatory markers and cIMT were comparable between groups. Long COVID symptoms were reported mainly by participants of group 1 [34 (23.6%) vs. 3 (3.8%), P < 0.001]. CONCLUSIONS: This study demonstrates insights into the long-term effects of COVID-19 infection in children. Evidence of endothelial activation without structural arterial changes was found. Persistent inflammation postinfection was absent, yet approximately one-quarter of the participants experienced long COVID symptoms, indicating potential differences in the pathophysiology of postacute COVID-19 infection in childhood.

Geoethics emphasizes responsible human interaction with the Earth, promoting ethical practices in the geosciences to ensure sustainability for current and future generations. UNESCO Global Geoparks (UGGps) are designated areas that support sustainable development by integrating geoconservation, geoeducation, and community engagement, thereby raising awareness of geological heritage. This quantitative study employed an online questionnaire (n = 798) to assess geoethical awareness among residents of all nine Hellenic UGGps, with the aim of profiling environmental engagement and perceptions. The results indicate a generally high level of geoethical awareness, with Sitia UGGp exhibiting the highest average mean score (M− = 8.98, SD− = 1.34), reflecting strong community support and effective outreach efforts. In contrast, Lavreotiki UGGp (M− = 8.48, SD− = 1.15) and Psiloritis UGGp (M− = 8.33, SD− = 1.36) scored lower in areas such as community engagement and geotourism, suggesting opportunities for targeted improvement. Regional differences suggest that management, visibility, and local context significantly influence public perceptions. Cluster analysis identified four respondent profiles: (a) highly engaged environmental stewards (28.7%), (b) supportive but selective advocates (40.5%), (c) moderately indifferent participants (26.9%), and (d) disengaged or critical respondents (3.9%). Demographic factors such as age, residence, prior visits to Hellenic UGGps, and education significantly differentiated these groups. Mapping geoethical awareness provides a valuable tool for assessing societal benefits and enhancing the governance of UGGps. Overall, the findings underscore the need to shift from an anthropocentric to a more geocentric worldview that prioritizes the well-being of both humanity and Earth’s systems.

The geotectonic units of the External Hellenides Carbonate Platform are characterized by continuous sedimentation from the Triassic onward. This was terminated by widespread synorogenic flysch sequences of great thicknesses, deposited in foreland basins during the collision stage extending from the Paleogene up to Pliocene in the most external parts. A comprehensive dataset concerning the synorogenic Messinian-Pliocene locations of the Hellenic territory and the available published calcareous nannofossil biostratigraphic results, has been constructed, aiming to standardize the available data and provide realistic biochronologic estimations, according to the available and updated astrobiochronological approaches (e.g., Lourens et al., 2004; Raffi et al., 2006; Backman et al., 2012; Agnini et al., 2017). In addition, a series of new locations with their unpublished calcareous nannofossil biostratigraphic determinations (e.g., Triantaphyllou, 2017; Triantaphyllou et al., 2025), are incorporated to the dataset, providing a useful framework for geodynamic interpretations and correlations in the eastern Mediterranean and beyond. The geographical distribution of all the existing data is presented in a series of geological maps arranged according to each nannofossil biozone. The presented dataset contributes to a better understanding of the spatiotemporal impact on biostratigraphic assignments of the different geological-geotectonic origin deposits, practically dating the most recent evolution stages of the Hellenic arc, as also of the factors limiting the distribution and controlling the presence of the widely used nannofossil biostratigraphic indices in the eastern Mediterranean realm. Most of the micropaleontological/geological material associated with the constructed nannofossil biostratigraphy dataset, is already incorporated into the Micropaleontology Collection at the Laboratory of Historical Geology and Biogeosciences, NKUA.

OBJECTIVES: Αn HIV-1 outbreak was identified among people who inject drugs (PWID) in Thessaloniki, Greece, during 2019-2021. We aimed to investigate the characteristics of this outbreak by means of molecular epidemiology. METHODS: We analysed 57 sequences from PWID sampled in Thessaloniki during 2019-2023. Phylogenetic trees were inferred using all subtype A sequences from PWID sampled since 1999 in Greece and reference sequences (n=4824). Phylodynamic analysis was performed using the Bayesian birth-death skyline serial model. RESULTS: Most of the 57 study sequences belonged to sub-subtypes A6 (49, 86%) and A1 (4, 7%). Phylogenetic analysis revealed that two (50%) A1 sequences clustered together and 47 (95.9%) A6 sequences fell within three PWID-specific phylogenetic clusters. The 99.6% and 77.9% of pairwise genetic distances within the largest and second largest PWID clusters were lower than 0.015 substitutions/site. Using a more stringent threshold (0.0015 substitutions/site), we identified five networks of sequences from PWID infected within 1 year. The effective reproduction number (R(e)) started to increase at the beginning of 2019 and remained high almost until the end of 2021. The estimated time from HIV-1 infection to diagnosis showed an increasing trend during 2020-2023 (p<0.001). CONCLUSIONS: The regional clustering of the PWID sequences and their low genetic divergence confirm its local spreading and the recent nature of the outbreak. Using a stringent genetic distance threshold, we showed that HIV-1 transmission occurred among large groups of PWID. The time of epidemic growth coincided with the time of the initial identification, and HIV-1 transmission continued at high rates until 2021.

The aminolysis reaction between MN’’2 (N’’ = N(SiMe3)2; M = Fe, Co, Ni) and the neutral pro-ligand 6,6'-(1,4-phenylenebis(propane-2,2-diyl))bis(2,4-di-tert-butylphenol) (LH2) affords the low coordinate, isomorphous, monomeric bis-aryloxide complexes (2-M) (M =...

Unidirectional propagation based on surface magnetoplasmons (SMPs) has recently been realized at the interface of magnetized semiconductors. However, usually SMPs lose their unidirectionality due to nonlocal effects, especially in the lower trivial band gap of such structures. More recently, a truly unidirectional SMP (USMP)hasbeen demonstrated in the upper topological nontrivial band gap, but it supports only a single USMP, limiting its functionality. In this work, we present a fundamental physical model for multiple, robust, truly topological USMP modes at terahertz (THz) frequencies, realized in a semiconductor-dielectric-semiconductor (SDS) slab waveguide under opposing external magnetic fields. We analytically derive the dispersion properties of the SMPs and perform numerical analysis in both local and nonlocal models. Our results show that the SDS waveguide supports two truly (even and odd) USMP modes in the upper topological nontrivial band gap. Exploiting these two modes, we demonstrate unidirectional SMP multimode interference (USMMI), being highly robust and immune to backscattering, overcoming the back-reflection issue in conventional bidirectional waveguides. To demonstrate the usefulness of this approach, we numerically realize a frequency and magneti cally tunable arbitrary-ratio splitter based on this robust USMMI, enabling multimode conversion. We, further, identify a unique index-near-zero (INZ) odd USMP mode in the SDS waveguide, distinct from conventional semiconductor-dielectric-metal waveguides. Leveraging this INZ mode, we achieve phase modulation with a phase shift from −π to π. Our work expands the manipulation of topological waves and enriches the field of truly nonreciprocal topological physics for practical device applications.

Childhood acute lymphoblastic leukaemia (chALL) remains the most prevalent malignancy in children and adolescents. Improving risk stratification and providing personalized prognosis and treatment remain major clinical challenges. Herein, we analysed the clinical utility of NEAT1 lncRNA for the prognosis and prediction of treatment outcome of childhood B-cell precursor ALL (chB-ALL). NEAT1_1 isoform was quantified in bone marrow samples of chB-ALL patients at diagnosis (n = 160) and at the end of induction (n = 108) of ALL-BFM protocol, and in age-matched healthy children (n = 68). Relapse and death served as clinical end-points for survival analysis. Bootstrap analysis was performed for internal validation and decision curve analysis assessed the clinical net benefit for chB-ALL prognosis. Our analysis showed that chB-ALL patients with NEAT1 overexpression at diagnosis are at significantly higher risk for progression (HR = 2.957, 95% CI: 1.122-7.790, p = 0.011) and worse survival (HR = 5.832, 95% CI: 1.259-27.01, p = 0.012), independently of clinicopathological and treatment data. Moreover, NEAT1-fitted multivariate models resulted in improved risk stratification compared to the conventional disease markers of white blood cells, bone marrow response and minimal residual disease, while decision curve analysis highlighted the superior clinical net benefit for chB-ALL prognosis. In conclusion, NEAT1 overexpression constitutes a powerful, independent predictor of poor treatment outcomes and disease progression of chB-ALL, providing refined stratification of patient's risk.

Given the critical role of zeroing neural networks (ZNN) in various fields and the practical demand for models in effectively resisting real-time noise, this study introduces a novel anti-noise integral zeroing neural network (AN-IZNN) model alongside its enhanced counterpart (EAN-IZNN), for the applications of matrix problem solving. Theoretical analysis demonstrates their ability to achieve convergence even under different noise conditions. Both theoretical analyses and simulation validations highlight the superior performance of the proposed models over existing neural network models. Notably, the root mean square error of the proposed AN-IZNN and EAN-IZNN models is reduced by 92.6249% and 91.4178%, respectively, compared to scenarios without the proposed method, demonstrating the effectiveness of the solution.

BACKGROUND & AIMS: The year 2023 marked the 10-year anniversary of the launch of direct-acting antivirals (DAAs) for the treatment of hepatitis C virus (HCV). Monitoring HCV treatment trends by country, region, and globally is important to assess progress toward the World Health Organization's 2030 elimination targets. Additionally, the historical patterns can help predict the treatment uptake for future therapies for other liver diseases. METHODS: The number of people living with HCV (PLHCV) treated between 2014-2023 across 119 countries was estimated using national HCV registries, reported DAA sales data, pharmaceutical companies' reports, and estimates provided by national experts. For the countries with no available data, the average estimate of the corresponding Global Burden of Disease region was used. RESULTS: An estimated 13,816,000 (95% uncertainty intervals: 13,221,000-16,415,000) PLHCV were treated, of whom 12,748,000 (12,226,000-15,231,000) were treated with DAAs, of which 11,081,000 (10,542,000-13,338,000) were sofosbuvir-based DAA regimens. Country-level data accounted for 97% of these estimates. In high-income countries, there was a 41% drop in treatment from its peak, and reimbursement was a large predictor of treatment. In low- and middle-income countries, price played an important role in expanding treatment access through the public and private markets, and treatment continues to increase slowly after a sharp drop at the end of the Egyptian national program. CONCLUSIONS: In the last 10 years, 21% of all HCV infections were treated with DAAs. Regional and temporal variations highlight the importance of active screening strategies. Without program enhancements, the number of treated PLHCV stalled in every country/region, which may not reflect a lower prevalence but may instead reflect the diminishing returns of existing strategies. IMPACT AND IMPLICATIONS: Long-term hepatitis C virus (HCV) infection can lead to cirrhosis and liver cancer. Since 2014, these infections can be effectively treated with 8-12 weeks of oral therapies. In 2015, the World Health Organization established targets to eliminate HCV by 2030, which included treatment targets for member countries. The current study examines HCV treatment patterns across 119 countries and regions from 2014 to 2023 to assess the impact of national programs. This study can assist physicians and policymakers in understanding treatment patterns within similar regions or income groups and in utilizing historical data to refine their strategies in the future.

Piezoelectric phononic-crystal plates, structured on their surface with metallic strips introducing electric-circuit loads, exhibit a tunable frequency-dispersion behaviour, nondestructively controlled in real time. Under an appropriate choice of boundary conditions through these loads, obeying a space-time propagation rule, it is demonstrated experimentally that these systems support nonreciprocal propagation of Lamb-like guided modes in their interior. The observations combined with numerical calculations confirm a broadband translation of the dispersion curves in the frequency-wavenumber space depending on the modulation speed. A careful analysis reveals a simple vector-rule relationship between the static bands and those induced by the time modulation of the external loads in the dispersion diagram. The device proposed in this study, offering dynamic changes in the electric boundary conditions by making use of switches driven by a microcontroller, thus, becomes an efficient tool not only for the realization of real-time control of elastic waves but also, and more importantly, a versatile platform for a robust generation of nonreciprocity effects in tunable, low-dimensional systems.

Abstract Ocean water clarity, influenced by marine chlorophyll concentration, significantly alters the distribution of shortwave radiation in the water column. This work aims to assess the effects of varying chlorophyll on the upper-ocean physical properties and their subsequent impact on the atmosphere, using a coupled ocean-atmosphere regional model for the Mediterranean and Black Seas. We performed 11-year (2011–2021) twin-simulation experiments based on different chlorophyll concentrations to estimate the penetration of solar radiation in the ocean. The first simulation used a monthly climatology field of chlorophyll concentrations derived from satellite observations, while in the second experiment, the chlorophyll concentration was kept constant at 0.05 mgm−3 \$\mathrm{m}\mathrm{g}\ {\mathrm{m}}^{-3}\$, representing clear water conditions. Results show that radiative heating driven by chlorophyll amplifies the seasonal cycle of temperature in the upper layers, leading to increased surface warming in summer and surface cooling in winter. Also, higher surface chlorophyll contributes to cooling in subsurface layers throughout the year due to its shading effect. The temperature response to chlorophyll variations is controlled by the mixed layer depth and a balance between (a) direct near-surface radiative heating due to the chlorophyll absorption and (b) indirect cooling resulting from vertical turbulent mixing processes with subsurface waters. The atmosphere moderates the seasonal sea surface temperature (SST) response caused by chlorophyll differential heating primarily through changes in latent heat flux. Ultimately, our simulations suggest that increased surface chlorophyll concentrations enhance the Mediterranean overturning circulation, highlighting the necessity of incorporating realistic optical forcing into regional climate modeling studies.

Abstract Ocean water clarity, influenced by marine chlorophyll concentration, significantly alters the distribution of shortwave radiation in the water column. This work aims to assess the effects of varying chlorophyll on the upper-ocean physical properties and their subsequent impact on the atmosphere, using a coupled ocean-atmosphere regional model for the Mediterranean and Black Seas. We performed 11-year (2011–2021) twin-simulation experiments based on different chlorophyll concentrations to estimate the penetration of solar radiation in the ocean. The first simulation used a monthly climatology field of chlorophyll concentrations derived from satellite observations, while in the second experiment, the chlorophyll concentration was kept constant at 0.05 \$\mathrm{m}\mathrm{g}\ {\mathrm{m}}^{-3}\$, representing clear water conditions. Results show that radiative heating driven by chlorophyll amplifies the seasonal cycle of temperature in the upper layers, leading to increased surface warming in summer and surface cooling in winter. Also, higher surface chlorophyll contributes to cooling in subsurface layers throughout the year due to its shading effect. The temperature response to chlorophyll variations is controlled by the mixed layer depth and a balance between (a) direct near-surface radiative heating due to the chlorophyll absorption and (b) indirect cooling resulting from vertical turbulent mixing processes with subsurface waters. The atmosphere moderates the seasonal sea surface temperature (SST) response caused by chlorophyll differential heating primarily through changes in latent heat flux. Ultimately, our simulations suggest that increased surface chlorophyll concentrations enhance the Mediterranean overturning circulation, highlighting the necessity of incorporating realistic optical forcing into regional climate modeling studies.

Metalloporphyrins on interfaces offer a rich playground for functional materials and hence have been subjected to intense scrutiny over the past decades. As the same porphyrin macrocycle on the same surface may exhibit vastly different physicochemical properties depending on the metal center and its substituents, it is vital to have a thorough structural and chemical characterization of such systems. Here, we explore the distinctions arising from coverage and macrocycle substituents on the closely related ruthenium octaethyl porphyrin and ruthenium tetrabenzo porphyrin on Ag(111). Our investigation employs a multitechnique approach in ultrahigh vacuum, combining scanning tunneling microscopy, low-energy electron diffraction, photoelectron spectroscopy, normal incidence X-ray standing wave, and near-edge X-ray absorption fine structure, supported by density functional theory. This methodology allows for a thorough examination of the nuanced differences in the self-assembly, substrate modification, molecular conformation and adsorption height.Metalloporphyrins on interfaces offer a rich playground for functional materials and hence have been subjected to intense scrutiny over the past decades. As the same porphyrin macrocycle on the same surface may exhibit vastly different physicochemical properties depending on the metal center and its substituents, it is vital to have a thorough structural and chemical characterization of such systems. Here, we explore the distinctions arising from coverage and macrocycle substituents on the closely related ruthenium octaethyl porphyrin and ruthenium tetrabenzo porphyrin on Ag(111). Our investigation employs a multitechnique approach in ultrahigh vacuum, combining scanning tunneling microscopy, low-energy electron diffraction, photoelectron spectroscopy, normal incidence X-ray standing wave, and near-edge X-ray absorption fine structure, supported by density functional theory. This methodology allows for a thorough examination of the nuanced differences in the self-assembly, substrate modification, molecular conformation and adsorption height.

The main objective of modern organizations is to acquire a long-term competitive advantage, so that they may cope with the requirements of organizations' complex and unstable environment. In this context, several companies try to transform themselves into Learning Organizations. The aim of this paper is to  reveal whether the awarded companies in Greece, in terms of working environment, provide learning opportunities to their employees within their working environment.  The quantitative method was employed, and a reliable questionnaire was filled by 80 employees, who work for an awarded company as one of the best companies in Greece, by a certified international organization called "Great Place to Work", DLOQ-Dimensions of the Organization Learning Questionnaire with 55 items, was selected as a valid and reliable instrument, in order to evaluate the dimensions of organizational learning and organizational performance. The findings of the current research, indicate that the company under study, has the characteristics of a Learning Organization and that the adoption of the seven dimensions of the Learning Organization has a positive impact on organizational performance. According to the study results, the subject company, identifies the importance of developing a learning culture in order to increase its performance and due to this fact, it takes all actions required for the development and training of human resources, so that it may reach its objectives.

COVID-19 pandemic had a profound negative impact on people’s personal and social life. In this chapter, after some conceptual clarifications, we provide insights into the effects of ostracism on people’s well-being as individuals, partners, and group members. Specifically, we explore (a) individual- and personality-based risk factors of ostracism (intrapersonal level); (b) deprivation of social touch, disruption of empathy and social stigmatization in interpersonal relations (interpersonal level); and (c) disruption of social identity, social stigmatization and rise in prejudiced, discriminatory, and xenophobic tendencies within groups (intergroup level). The contribution of this chapter lies in proposing an interplay among intrapersonal, interpersonal, and intergroup dimensions of identity, that is, a multi-level conceptualization of ostracism during the covidian era. By integrating theoretical arguments and research findings, we support the view that personal identity commitment and identification with social groups have similar roots, both based on the individual’s need to formulate meaningful connections to the world and, thus, cope with as well as prevent ostracism. The implications of the interplay between personal and social identity for the measurement of ostracism are also discussed. Next, strategies for tackling ostracism during the pandemic or similar widespread crises are proposed. Finally, avenues for future research are suggested.

The Gulf of Corinth (GoC), derived from a geologically young active rift, offers a unique opportunity to study changes in environmental conditions during the Quaternary period in a region where long sequences are few. Due to periods of isolation during Quaternary lowstands, the water conditions were not favorable for the occurrence of conventional palaeoceanographical proxies such as planktonic foraminifera. We present here the first almost continuous record of phytoplankton proxies (dinoflagellate cysts) and freshwater palynomorphs (green algae) for the past 1.1 Myr aiming to provide a comprehensive insight into palaeoceanographic variability between glacial and interglacials cycles. Core M0078A retrieved during the IODP expedition 381 contains a rich and diverse dinoflagellate cyst assemblage, sorted into two major ecogroups, representing alternations between marine and brackish conditions. Our results allow for the first time the reconstruction of the Gulf environmental history of connection and disconnection from marine conditions from late Pleistocene to Holocene (1.1Ma – present). Dinocysts and other palynomorphs (NPPs) suggest that the GoC was repeatedly isolated and reconnected to the Mediterranean Sea during global sea-level lowstands associated with glacial intervals. These combined proxies suggest that marine water flowed into the GoC during the eustatic highstands associated with interglacial intervals. The dinocyst assemblages show a close affinity to modern assemblages from the Black, Caspian, and Marmara Seas.

We present a comprehensive investigation into the synthesis, phase evolution and valence state of vanadium (V) in V1−xFexO2 (x = 0 %, 0.5 %, 0.75 %, 1.0 %) compounds. Polycrystalline samples have been synthesized with solid-state reaction method, followed by thermal annealing. X-Ray Powder Diffraction (XRPD) analyzed by Le Bail method revealed the transformation from monoclinic (M1) phase (space group: P21∕c) to triclinic (T) one with increasing Fe concentration. Additionally, a monoclinic (M2) phase (space group: C2∕m) emerged at 1.0 % Fe doping. Temperature-dependent XRPD and diffuse reflectance measurements elucidated the phase transitions during heating cycles, showing the impact of Fe doping on the system’s behavior. The construction of a complete phase diagram for the V1−xFexO2 system (x ≤ 1.0 %) was achieved, addressing ambiguities in the low-Fe concentration region. X-ray Photoelectron Spectroscopy (XPS) further confirmed the influence of Fe doping on the vanadium valence states, indicating an increase of V5+ sites and therefore a lattice distortion and stabilization of the triclinic phase. The metal-insulator transition temperature (TMIT) appears to be almost constant. Post-annealing led to the reinstatement of the M1 phase in all samples, and a modified phase diagram was constructed. The accompanied decrease of V5+ ions contributed to the destabilization of the T and M2 phases, favoring the thermodynamically stable M1 phase. The findings provide valuable insights into the complex phase behavior of V1−xFexO2 compounds, showcasing a significant interplay between charge redistribution, the vanadium valence state, and the oxygen defects of the system.

BACKGROUND: Accurate population size estimation of people who inject drugs (PWID) is essential for evidence-based drug policy and service planning, yet it remains challenging. An emerging HIV outbreak in Thessaloniki, Greece's second-largest city, highlighted the urgent need for evidence-based population size estimates. METHODS: We applied capture-recapture analysis to five respondent-driven sampling (RDS) rounds conducted during 2019-2021 to estimate PWID population size in Thessaloniki for the 2019-2021 period. These RDS rounds were part of a community-based program aimed at increasing HIV/HCV testing and linkage to care among PWID. We treated each RDS round as a capture source and used log-linear models to estimate PWID population size (past 12 months and past 30 days), accounting for potential dependencies between rounds through interaction terms. We then estimated HIV/HCV disease burden and assessed prevention and harm reduction service coverage against international standards (HIV testing, OAT, NSP). RESULTS: Based on data from 1093 unique participants across five rounds (53.9% currently injecting, 20.3% currently in OAT), capture-recapture analysis estimated 1512 PWID (95% confidence interval (CI): 1345-1741) who had injected drugs in the past 12 months. The estimated prevalence of injecting drug use was 0.22% (95% CI: 0.20-0.25) among adults aged 18-64 years. We estimated 106 people living with HIV (95% uncertainty interval (UI): 83-130) and 945 HCV-antibody-positive individuals (95% UI: 815-1077) among PWID. Needle and syringe program coverage was 36 (95% CI: 31-40) syringes per PWID in 2021. CONCLUSION: Based on this community-based population size estimate, the prevalence of injection was nearly double the official national Greek average. The annual distribution of syringes should increase by 5.6 times to reach the WHO target (≥200 syringes/PWID/year). These findings demonstrate how community-based programs with multiple RDS rounds can also yield population estimates essential for evidence-based drug policy interventions.

New presentations of Specht modules of symmetric groups over fields of characteristic zero have been obtained by Brauner, Friedmann, Hanlon, Stanley and Wachs. These involve generators that are column tabloids and relations that are Garnir relations with maximal number of exchanges between consecutive columns or symmetrization of Garnir relations with minimal number of exchanges between consecutive columns. In this paper, we examine Garnir relations and their symmetrization with any number of exchanges. In both cases, we provide sufficient arithmetic conditions so that the corresponding quotient is a Specht module. In particular, in the first case this yields new presentations of Specht modules if the parts of the conjugate partition that correspond to maximal number of exchanges greater than 1 are distinct. These results generalize the presentations mentioned above and offer an answer to a question of Friedmann, Hanlon and Wachs. Our approach is via representations of the general linear group.

This study reviewed the benefits of outdoor activities and educational programs that take place in nature in terms of the cognitive and mental development of children. Research has highlighted the benefits offered to children by their participation in experiential activities that take place outdoors and are related to natural phenomena. These activities help children realize how important it is to conserve nature and protect sites of world heritage, thus becoming active citizens in the future. In this study, the uniqueness of Syros Island is presented, emphasizing the need for the world-renowned geological heritage of Syros to be preserved and promoted, both for the scientific community and for the public, with the aim of establishing a geopark in Apano Meria, as proposed by local authorities, along with a local museum. In this context, a working methodology was developed involving the design and implementation of a pilot educational program combining field-based activities, guided interpretation, and interactive learning tools. An indicative educational program was piloted with primary and secondary school students, as well as postgraduate students from the University of Athens. Recognizing the important role of geoparks in school education, the program focused on the rare geological phenomena on the northern side of Syros and was adapted to the characteristics of each participant age group.

The Rab3 protein family is composed of a series of small GTP-binding proteins, including Rab3a, Rab3b, Rab3c, and Rab3d, termed Rab3s. They play crucial roles in health, including in brain function, such as through the regulation of synaptic transmission and neuronal activities. In the high-energy-demanding and high-traffic neurons, the Rab3s regulate essential cellular processes, including trafficking of synaptic vesicles and lysosomal positioning, which are pivotal for the maintenance of synaptic integrity and neuronal physiology. Emerging findings suggest that alterations in Rab3s expression are associated with age-related neurodegenerative pathologies, including Alzheimer's disease, Parkinson's disease, and Huntington's disease, among others. Here, we provide an overview of how Rab3s dysregulation disrupts neuronal homeostasis, contributing to impaired autophagy, synaptic dysfunction, and eventually leading to neuronal death. We highlight emerging questions on how Rab3s safeguards the brain and how their dysfunction contributes to the different neurodegenerative diseases. We propose fine-tuning the Rab3s signaling directly or indirectly, such as via targeting their upstream protein AMPK, holding therapeutic potential.

People who inject drugs (PWIDs) remain underserved in HIV care. Evidence on rapid antiretroviral therapy (ART) for PWID is limited. We evaluated feasibility, effectiveness, safety, and patient-reported outcomes (PROs) for rapid initiation of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) supported by a peer navigation in Greece. This is a single-arm, multicenter pilot study including PWIDs (≥18 years) newly diagnosed or relinking after >3 months off ART. Participants started BIC/FTC/TAF on the same day or within 7 days and received peer navigation for 48 weeks. Co-primary endpoints were Week-24 virologic suppression (HIV-1 RNA < 50 copies/mL; FDA Snapshot) and grade 3-4 adverse events (AEs). Secondary endpoints included complete-case suppression at Weeks 24/48, CD4 recovery, retention, and PROs. Outcomes were compared with historical controls from the same centers. Thirty-seven participants were enrolled (83.8% male; median age 33.3 years). Median time to ART was 0 days (vs 78 in controls, p < 0.001). Retention was 67.6% at Week 24 and 54.1% at Week 48. In the primary (FDA Snapshot) analysis, suppression was 62.2% and 54.1% at Weeks 24 and 48; in complete-case analyses, results were 92.0% and 100%, respectively. Mean CD4 count increased by 208 cells/μL (95% CI 141-275) at Week 48. Quality of life improved and symptom burden decreased. No grade 3-4 AEs occurred. Rapid BIC/FTC/TAF with peer navigation eliminated delays to ART and achieved favorable virologic, immunologic, and PROs among those retained, with good tolerability. Despite retention challenges, this model appears feasible for PWID and may help close HIV care gaps toward UNAIDS 95-95-95 targets.

The index-near-zero (INZ) mode exhibits novel spatial phase invariance characteristics. Recent research has focused on exploring INZ-related phenomena using metamaterials, metasurfaces, and photonic crystal (PhC) structures. However, most currently proposed INZ modes lack flexible control and are challenging to implement. Additionally, INZ modes near the Dirac point in PhCs typically operate only at specific frequencies. In this study, Chern PhCs composed of simple magneto-optical materials are utilized to regulate topologically unidirectional INZ electromagnetic modes by adjusting the air thickness and varying the magnitude of an external magnetic field. Due to the unidirectional robustness and near-zero phase shift characteristics of the INZ mode, three application scenarios are proposed: a phase inverter, a perfect 50/50 splitter, and high-performance broadband sensors. This work provides a new platform and approach for optical communication and computing.

We use the Worldwide Bioclimatic Classification system to identify changes in the bioclimatic characteristics of Greece between the present and the recent past, by comparing two reference periods: 1961-1990 and 1991-2020. This classification system, developed by Rivas-Martínez et al. (2011), defines the relationship between climatic variables, expressed through bioclimatic indices, and the corresponding distribution of natural vegetation. It generates distinct climatic units known as isobioclimates, which represent specific combinations of macrobioclimates, thermotypes, and ombrotypes. These isobioclimates link climate to ecosystems and allow the characterization of environmental diversity across spatial and temporal scales. The climate input for the system consists of mean, maximum, and minimum monthly temperatures and accumulated monthly precipitation. For this study, we use the ERA5-Land monthly mean data sets from the Copernicus Climate Data Store (CDS), averaged over the two study periods. Calculation of bioclimatic indices and mapping of the isobioclimates are performed using ArcGIS. Preliminary results indicate a shift in the isobioclimatic structure of Greece towards warmer thermotypes and drier ombrotypes. These changes are mostly evident in southern and lowland regions and may reflect increasing aridity and temperatures, suggesting an intensification of ecological stress and wildfire risk, with potential consequences for biodiversity. This work will be extended with the use of regional climate model projections to explore possible future bioclimatic changes in Greece, that will help to assess how climate change may affect vegetation types and inform strategies for ecosystem management in the coming decades.

Agia Bay is located on the southeastern coast of Lemnos Island. The coastal area today is characterized by aeolian sandy deposits (dunes). The systematic investigation of a 15.5-m long sediment core from the coastal plain of Agia Bay aimed to shed light to the paleoenvironmental evolution of the area that prehistoric groups occupied. The exhaustive study of the faunal and floral remains of the deposits including benthic foraminifera, ostracods, mollusks, pollen, and dinoflagellate cysts as well as plant remains was further supported by sedimentological, micromorphological, and elemental analyses, magnetic susceptibility measurements, ERT, and absolute dating. Four main evolutionary stages have been identified since the Late Glacial. At the base of the sequence, the fluvial activity dominated the sedimentation in the area forming a small shallow wetland, while after 12,500 cal BP, a marine signal was observed at the wetland. At 7500 cal BP, the wetland increased in size and depth, whereas at 6000 up to 4000 cal BP, a connection of the wetland to the sea was established, and an inner lagoon formed. After 4000 cal BP, a nearshore environment developed due to the sea-level rise. Pollen assemblages record the occurrence of a mixed deciduous oak forest in the island interior around 6000 cal BP, while after 5000 cal BP, an expansion of Mediterranean vegetation, shaped by human activity, is inferred.

The persistence of high relapse rates and therapy resistance continues to challenge the effective management of multiple myeloma (MM). The identification of novel MM-specific molecular markers could ameliorate risk-stratification tools and accurately identify high-risk patients towards personalized prognosis and therapy. miRNA-seq analysis of CD138+ plasma cells (n = 24) unveiled miR-221-3p and miR-222-3p (miR-221/222 cluster) as the most downregulated miRNAs in R-ISS III compared to R-ISS I/II patients. Subsequently, miR-221/222 levels were quantified by RT-qPCR in CD138+ plasma cells of our screening cohort (n = 141), assessing patients' mortality and disease progression as clinical endpoints. Internal validation was performed by bootstrap analysis, while clinical benefit was estimated by decision curve analysis. Kryukov et al. (n = 149) and Aass et al. (n = 86) served as institutional-independent validation cohorts. Loss of miR-221/222 cluster was strongly associated with patients' short-term progression and poor overall survival, which was confirmed by Kryukov et al. and Aass et al. validation cohorts. Intriguingly, miR-221/222-fitted multivariate models offered superior risk-stratification within R-ISS staging and risk-based cytogenetics. Moreover, miR-221/222 loss could effectively discriminate optimal 1st-line treatment responders with inferior treatment outcome. Our study identified the loss of miR-221/222 cluster as a powerful independent predictor of patients' post-treatment progression, ameliorating prognosis and supporting precision medicine in MM.

A Bay of Biscay model configuration is used as a test case to assess the data-based consistency of ensemble-based ocean model uncertainties of several types: [A] built-in stochastic parameterizations at regional ocean scales, [B] ocean model response to a global atmospheric model ensemble and [C] both A and B simultaneously. Ensembles of varying length were generated. In addition to a seasonal-range ensemble, three medium-range ensembles were carried out over successive overlapping segments permitting to compare consistency metrics for different lead times. The largest spread was obtained for the C case, although most of the model uncertainties were attributable to the stochastic ocean parameterizations in A. We addressed the question of which ensemble type and lead time was able to provide the most realistic model uncertainties given observations of SST, sea level, and Chlorophyll a, using a theoretical and diagnostic consistency analysis framework expanded from Vervatis et al. (2021a). In our results, consistency was satisfactory for the stochastic ensembles of types A and C, for the “aged” error cases (but only marginally with respect to the “young” error cases), and whenever physical and biogeochemical uncertainty processes were active in the region and could be detected by the observational networks, such as the onset of the spring shoaling of the thermocline and the phytoplankton abundance primary bloom. Sea level empirical consistency was improved when a wide range of low- to high-frequency errors were included in the signal of dynamic atmospheric process in the data and in the model inverse barometer. These findings provide additional insight that can help configure ensemble-based methods in academic studies and in operational ocean forecasting systems.

Also used as ‘Start-up Research Tool and Reading List’ - recommended material and research tool for students, scholars and researchers: contains hundreds of academic / scientific papers, articles and studies globally.   -------------------------------------------------------------------1825 Direct citations since 2003 (updated May 16, 2025) ...... 1825  ετεροαναφορές/παραπομπές/αναφορές—απευθείας στο έργο—σε επιστημονικά περιοδικά, βιβλία, πρακτικά συνεδρίων, διδακτορικές διατριβές, μεταπτυχιακές διατριβές, κεφάλαια βιβλίων,  κ.ά. (από το 2003 έως 15/05/2025).

Here we report definite results on the mathematical metabolization of Maxwell’s equations in one of the building units, most commonly met in practice. We investigate the static/quasi-static case of a linear, homogeneous and isotropic magnetic and dielectric cylinder of intrinsic susceptibility, xint, subjected to an external potential/field, Uext/Fext, of any form on the plane normal to the directional axis, produced by a primary source that resides at the outside space. Specifically, here we address analytically a magnetic and dielectric cylinder of seemingly infinite length along the z axis, subjected to an external potential/field, Uext/Fext, that does not vary along the z axis, as well. An expansion-based mathematical approach is employed, enabling direct access to universal expressions of the response of the magnetic and dielectric cylinder, i.e., the internal potential/field, Uint/Fint, produced by the secondary source of bound charges that is originally induced by the external potential/field, Uext/Fext. Accordingly, ready-to-use expressions of the total potential/field, U=Uext+Uint/F=Fext+Fint, and of the polarization, P, of the magnetic and dielectric cylinder are directly obtained. These universal expressions are applicable to every distinct problem of different Uext/Fext, without the need to tackle it mathematically, every time, from the beginning. Interestingly, the depolarization factor, N, and extrinsic susceptibility, xext, are degenerate, obtaining a constant value irrespectively of the mode of the external potential/field, Uext/Fext. These universal expressions between Uint-Uext, U-Uext, Fint-Fext, F-Fint and P-Fext provide effective means to understand, design and realize cylindrical building units with specific characteristics.

We investigate the effects of non-synchronous trading on volatility spillover for the G-7 equity markets during the Eurozone sovereign debt crisis (ESDC) and the Covid-19 pandemic crisis. For data synchronisation we utilise ΜΑ(1) adjusted return series to estimate the Baba-Engle-Kraft-Kroner (BEKK) and the dynamic conditional correlation (DCC) models. We also consider the use of realised kernels as explanatory variables in the variance equation. In this set up, the contagion effects during crises periods are more perceptible, as the spikes are easier to interpret. We also check the robustness of our main results by applying, wavelet coherence analysis to G-7 major equity indices with realised kernels, as well as local Gaussian correlations (LGC). Our findings suggest the empirical significance of the synchronisation effects for the US and the other G-7 equity markets. We also conclude that realised kernels is an effective tool for mitigating non-synchronous effects. These results underline the significance of quantifying the synchronisation effects in equity markets as well as international portfolio diversification strategies.

Air–sea interactions play a pivotal role in shaping cyclone development and evolution. In this context, this study investigates the role of ocean optical properties and solar radiation penetration in modulating subsurface heat content and their subsequent influence on the intensity of Mediterranean cyclones. Using a regional coupled ocean–wave–atmosphere model, we conducted sensitivity experiments for Storm Daniel (2023) comparing two solar radiation penetration schemes in the ocean model component: one with a constant light attenuation depth and another with chlorophyll-dependent attenuation based on satellite estimates. Results show that the chlorophyll-driven radiative heating scheme consistently produces warmer sea surface temperatures (SSTs) prior to cyclone onset, leading to stronger cyclones characterized by deeper minimum mean sea-level pressure, intensified convective activity, and increased rainfall. However, post-storm SST cooling is also amplified due to stronger wind stress and vertical mixing, potentially influencing subsequent local atmospheric conditions. Overall, this work demonstrates that ocean bio-optical processes can meaningfully impact Mediterranean cyclone behavior, highlighting the importance of using appropriate underwater light attenuation schemes and ocean color remote sensing data in coupled models.

Air–sea interactions play a pivotal role in shaping cyclone development and evolution. In this context, this study investigates the role of ocean optical properties and solar radiation penetration in modulating subsurface heat content and their subsequent influence on the intensity of Mediterranean cyclones. Using a regional coupled ocean–wave–atmosphere model, we conducted sensitivity experiments for Storm Daniel (2023) comparing two solar radiation penetration schemes in the ocean model component: one with a constant light attenuation depth and another with chlorophyll-dependent attenuation based on satellite estimates. Results show that the chlorophyll-driven radiative heating scheme consistently produces warmer sea surface temperatures (SSTs) prior to cyclone onset, leading to stronger cyclones characterized by deeper minimum mean sea-level pressure, intensified convective activity, and increased rainfall. However, post-storm SST cooling is also amplified due to stronger wind stress and vertical mixing, potentially influencing subsequent local atmospheric conditions. Overall, this work demonstrates that ocean bio-optical processes can meaningfully impact Mediterranean cyclone behavior, highlighting the importance of using appropriate underwater light attenuation schemes and ocean color remote sensing data in coupled models.

The macrocyclic biquinazoline ligand, H-Mabiq, presents a central and a peripheral site for the coordination of metal ions, making the adsorption on solid surfaces promising for the creation of self-assembled bimetallic two-dimensional platforms. Here, we apply an on-surface metalation strategy under ultra-high vacuum conditions to guide the synthesis of metalated species and study sequential metalation patterns. We find that cobalt (as well as iron) metalation on the Ag(111) surface preferentially occurs at the macrocyclic centre without further metal coordination to the peripheral site. Nevertheless, starting from a densely packed, self-assembled H-Mabiq monolayer, the modification of the central cavity by Co is accompanied by an unusual, metalation-induced phase transformation which gives evidence of modified lateral / interfacial interactions. The selective metalation of one molecular site opens up an on-surface route to create bimetallic networks incorporating select metal ions at different locations.

In semantic fluency tasks, participants employ semantic search strategies (clustering and switching) to facilitate word retrieval. Clustering involves producing sequences of related words, while switching refers to shifting between different semantic categories. Analyzing these strategies provides insights into the structure of the mental lexicon in both native and foreign language. This study explored these strategies in a semantic fluency task with the prompt ‘My country’. Fifty—three Greek learners of Spanish completed the task in both their native language (Greek) and foreign language (Spanish). Clustering was analyzed by the number of clusters, the mean cluster size and the type of cluster, based on the type of association among its members. Switching was measured by the number of transitions. Results revealed that participants produced more and longer clusters in their L1 than in SFL responses, reflecting a more developed and interconnected mental lexicon in the L1. Additionally, they made more switches in L1, likely due to greater cognitive control and flexibility in their native language, which facilitates the cognitively demanding process of switching. Cluster types were consistent across both languages, suggesting that the internal structure of the prompt and cultural background significantly influence lexical organization regardless of language proficiency.

The volume brings together papers from the seminar »Johannine Literature« of the Society of New Testament Studies, offering a broad overview of current scholarship after the decline of the Semeia Source hypothesis. The contributors explore central issues of Johannine exegesis through detailed case studies and broader theological reflections. Several essays focus on specific semeia narratives - including the notable example of John 21 - and analyze the literary and theological function of the term »semeia«. They address overarching questions such as the interplay of signs and faith or unbelief, the relationship between signs and works, and the role of semeia within the narrative structure and theological framework of the Gospel. Special attention is paid to interpretive practices, particularly Scriptural exegesis, as employed within the Johannine corpus. Furthermore, a concluding study on the interpretation of the Cana sign in the homilies of John Chrysostom offers a patristic reception-historical perspective. The contributors to this volume reflect the diversity of methodological approaches in current Johannine research and provide new impetus for ongoing scholarly engagement with the Gospel's theology, literary form, and historical reception.

Solving Lur'e equations plays a critical role in addressing linear-quadratic optimal control (LQOC) problems, especially in cases where the control cost matrices are singular. This paper introduces, for the first time, two novel zeroing neural network (ZNN) models—ZNNLE and ZNNLE-LQOC—specifically designed to solve the Lur'e equation system and the LQOC problem, respectively. The proposed models extend the applicability of the ZNN methodology to these challenging scenarios by offering robust and efficient solutions to time-varying matrix equations. Theoretical analyses confirm the validity of both models, while numerical simulations and practical applications demonstrate their effectiveness. Moreover, a comparative study with an enhanced alternating-direction implicit (ADI) method highlights the superior performance of the ZNNLE-LQOC model in solving LQOC problems.

Background: Scant research drawing from self-determination theory has examined how need-supportive and need-thwarting teaching can explain changes in relevant outcomes in Physical Education (PE). Aim: To explore to what extent two important outcomes in PE, perceived usefulness, and academic performance, change across a school year and whether these changes could be moderated by students’ perceptions of the degree to which their PE teacher is need supportive and/or need thwarting. Method: A total of 857 PE students (Mage = 14.67; SD = 0.74; 512 girls) from 32 secondary public schools participated in the three-wave, one-year longitudinal study. We used the Teaching Interpersonal Style Questionnaire, the students’ perceptions of academic performance, and the Perceived Importance of PE scale. Results: Two independent multilevel models were conducted to address our main research questions. Perceived need support positively predicted perceived PE usefulness and academic performance in PE at the beginning of the school year, while need thwarting negatively predicted these outcomes at the same time point. Interestingly, students who perceived their teacher being more need supportive in Time 1 showed a temporal decrease in perceived usefulness and academic performance in PE in Time 2, with this trend rebounding in Time 3. Need-thwarting teaching did not predict any changes in these two outcomes across a school year. Conclusions: Findings highlight the relevance of need-supportive teaching from the beginning of the course to achieve positive outcomes at the end of the academic year in PE. © 2025 Association for Physical Education.

The present study focuses on lived experiences of women in Greece who grew up with a guardian/parent who used alcohol and/or drugs excessively. The aim of the study was to gain in-depth understanding of how these experiences might have affected the quality of interpersonal relationships in adult life according to women’s reports. Twelve women in Greece, who all grew up with a parent/guardian that used alcohol and/or drugs excessively volunteered to take part in the study. The content of the interviews was analyzed with thematic analysis. This qualitative study revealed the lived experience of adult women who grew up in a familial environment where use of drugs and/or alcohol was excessive on a daily basis. The women reported a number of incidents that in their own understanding affected the quality of interpersonal relationships they have formed as adults. These include, among others, premature development, nurturing parents and forming poor relationships in adult life. Social support from significant others and forming a therapeutic alliance with a mental health professional were suggested by women as significant factors in alleviating traumatic memories. The study suggests that the need for a direct response to children’s needs who grow up with parents/guardians who use alcohol and/or drugs excessively, is significant in helping them develop quality relationships in adult life.

Europe has been investing increasingly in Lifelong Learning in recent years, possibly due to the emergence of new challenges that include population mobility and aging, as well as the transformation of the labor market due to the 4th industrial revolution. The purpose of the current paper is to address the need to employ lifelong learning policies and strategies to ensure equal access for women to the workplace and leadership in order to achieve labor integration. This paper discusses the presenting problem on data provided by independent research organisations being either public or private entities. Investing in Lifelong Learning programs in the workplace in Greece, to ensure women’s equal participation and transformation in leadership roles is also discussed in relation to segregation phenomena such as mobbing and sexual harassment. The present paper suggests that even though women may participate in Lifelong learning programmes, policies and strategies need to focus more on enhancing their soft and digital skills, in battling sexual harassment in the workplace and promoting equal access to leadership roles.

The rapid advancement of artificial intelligence (AI) and its integration into education create newopportunities for teaching natural sciences, offering dynamic tools that enhance the learning process. Thisstudy explores the use of ChatGPT as a support tool for teaching the age of the Earth in secondary education.Specifically, it presents a teaching scenario that combines active inquiry, collaborative learning, and criticalthinking, enabling students to interact with ChatGPT for searching, processing, and evaluating scientificinformation.The methodology is based on a blended learning model, which combines traditional teaching withtechnology. In this approach, students formulate questions, analyze responses, and compare ChatGPT’sinformation with established scientific sources. Additionally, the study investigates the challenges associatedwith AI use in education, such as the need for digital literacy, information reliability, and the role of teachersas mediators in the learning process. The proposed teaching scenario consists of three parts: 1. Introductoryteaching, where fundamental concepts about the age of the Earth and scientific dating methods are presented.2. Interaction with ChatGPT, where students organized into groups, pose questions, search for answers, andevaluate the information received. 3. Evaluation and feedback to compare learning progress and explorestudents' experience of using the tool.The quantitative analysis of the research is based on the following data collection tools: Pre-test andpost-test, measuring students’ cognitive development before and after using ChatGPT. Likert-scalequestionnaires to capture students' experience and their perception of the reliability and usefulness of suchtools. Statistical data analysis, extracting conclusions about the effectiveness of integrating ChatGPT intoteaching practices.It was concluded that the use of ChatGPT enhanced learning engagement, encouraged an enquiryapproach and the development of students' critical thinking. Through statistical analysis of the data, it wasconcluded that it improved the cognitive level and the degree of understanding of the concepts. However, ithighlights the need for appropriate pedagogical guidance and educational policy to ensure the proper use ofsuch AI tools in the educational process.Keywords: Artificial Intelligence, Education 4.0, ChatGPT, Age of the Earth (PDF) TEACHING THE AGE OF THE EARTH USING ChatGPT. Available from: https://www.researchgate.net/publication/392575642_TEACHING_THE_AGE_OF_THE_EARTH_USING_ChatGPT?channel=doi&linkId=68493f906b5a287c304a6fa1&showFulltext=true [accessed Sep 24 2025].

Complex-frequency excitations have recently attracted a lot of attention owing to their ability to solve a number of extraordinary challenges in photonics, such as overcoming losses without gain in metalenses and plasmonic waveguides and achieving virtual absorption. However, the totality of the works so far has been mainly computational or experimental, and a full theory of the complex dynamics enabled by these excitations is still missing. Here, we develop a fully analytical, exact time-domain theory for the dynamical scattering of these excitations by both sides of dielectric plates, which have been used to achieve virtual absorption. Our precise theoretical analysis confirms previous observations and, in addition, reveals a number of intriguing phenomena that were previously missed, such as discontinuities in the scattering of the outgoing electromagnetic field and release of the stored energy in distinct packets.

Rainbow trapping is a wave localization phenomenon in which different frequencies are spatially separated and con f ined by engineering dispersion through structural gradients. Initially demonstrated in tapered metamaterial systems, this concept has since been extended to plasmonic, photonic, acoustic, and elastic platforms, where graded-index profiles, chirped periodicities, and tapered geometries are used to control the group velocity and localize wave components at distinct spatial positions. These implementations enable high resolution spectral manipulation and form the foundation for broadband wave control. More recently, topological rainbow trapping has emerged as a robust alternative, leveraging topo logically protected states to achieve disorder-immune fre quency localization. This approach offers enhanced resilience to fabrication imperfections and opens new possibilities for scalable, integrated wave-based devices. In this review, we examine the physical mechanisms, system-specific implemen tations, and recent advances in both conventional and topo logical rainbow trapping. We also highlight promising appli cations ranging from optical communication and wavelength multiplexing to acoustic wave manipulation and vibrational energy harvesting and discuss key challenges and future directions in this rapidly evolving field.

We have theoretically investigated surface magnetoplasmons (SMPs) in an yttrium-iron-garnet (YIG) sandwiched waveguide. The dispersion demonstrated that this waveguide can support topological unidirectional SMPs. Based on unidirectional SMPs, magnetically controllable multimode interference (MMI) is verified in both symmetric and asymmetric waveguides. Due to the coupling between the modes along two YIG–air interfaces, the asymmetric waveguide supports a unidirectional even mode within a single-mode frequency range. Moreover, these modes are topologically protected when a disorder is introduced. Utilizing robust unidirectional SMP MMI (USMMI), tunable splitters have been achieved. It has been demonstrated that mode conversion between different modes can be realized. These results provide many degrees of freedom to manipulate topological waves.

We develop a full-wave electromagnetic (EM) theory for calculating the multipole decomposition in two-dimensional (2-D) structures consisting of isolated, arbitrarily shaped, inhomogeneous, anisotropic cylinders or a collection of such. To derive the multipole decomposition, we first solve the scattering problem by expanding the scattered electric field in divergenceless cylindrical vector wave functions (CVWFs) with unknown expansion coefficients that characterize the multipole response. These expansion coefficients are then expressed via contour integrals of the vectorial components of the scattered electric field evaluated via an electric field volume integral equation (EFVIE). The kernels of the EFVIE are the products of the tensorial 2-D Green’s function (GF) expansion and the equivalent 2-D volumetric electric and magnetic current densities. We validate the theory using the commercial finite element solver COMSOL Multiphysics. In the validation, we compute the multipole decomposition of the fields scattered from various 2-D structures and compare the results with alternative formulations. Finally, we demonstrate the applicability of the theory to study an emerging photonics application on oligomer-based highly directional switching using active media. This analysis addresses a critical gap in the current literature, where multipole theories exist primarily for three-dimensional (3-D) particles of isotropic materials. Our work enhances the understanding and utilization of the optical properties of 2-D, inhomogeneous, and anisotropic cylindrical structures, contributing to advancements in photonic and meta-optics technologies.

We examine utterances that contain merely contrastive, corrective, confirmative, and mirative focus structures in Greek. Through a perception experiment, we provide evidence regarding listener preferences about the syntactic position (‘high’ vs ‘low’) of the contrastively focused objects in SVO vs OVS patterns. The results suggest that listeners consider utterances with all four focus types acceptable, regardless of whether the sentential object appears in a ‘high’ or ‘low’ position in Greek, unlike other languages. Moreover, specific listener preferences are brought to light for each focus type: there is a clear preference for a ‘low’ position for mere focus, versus a ‘high’ one for corrective, while there is almost equal preference for both positions in the mirative and the confirmative structures. These findings support the distinction among the different types of contrastive focus with their respective (semantic, pragmatic, syntactic, and intonational) properties.

Research on environmental education in Greece highlights the urgent need to integrate climate change education into school curricula due to the severe impacts of the climate crisis. Despite growing social awareness, implementation is hindered by limited resources resulting from the economic crisis, fragmented content in textbooks, and inadequate legislation. Technological advancements present new opportunities for enhancing environmental education. This article reviews the current state of environmental education and proposes strategic directions to improve its effectiveness. A SWOT analysis identifies internal strengths and weaknesses, along with external opportunities and threats, while a PEST analysis evaluates political, economic, social, and technological influences. Based on these assessments, strategic goals and directions are outlined, focusing on the comprehensive integration of Environmental Education for Climate Change into Greece’s compulsory education system. Key proposals include the development of clear policies, structured guidelines, and curriculum adaptations to address the evolving challenges of climate change. A cohesive national framework is recommended to ensure the consistent implementation of environmental education across all educational levels. These initiatives aim to prepare future generations with the necessary knowledge and skills to mitigate and adapt to climate change, fostering a more sustainable society.

Cold air outbreaks (CAOs) are phenomena that occur across high latitudes during winter months and favor the development of extensive boundary layer clouds. As the boundary layer evolves, changes in cloud morphology often result in a stratocumulus to cumulus transition (SCT). The onset of precipitation is considered to be a key factor that leads to the break-up of the stratocumulus deck. In this modeling study we investigate the additional role that aerosols have on the SCT within a CAO event in the North Atlantic, by using prognostic fields for both aerosols and cloud droplet number concentrations (Nd). By using two chemical/aerosol schemes we assess and quantify the impact of aerosols on the SCT evolution. Our results indicate that the aerosol load and its chemical composition affect the timing of precipitation initiation and its magnitude and thus the break-up. However, the two schemes reveal contradictory results, which are mainly associated with different aerosol size and chemical composition partitioning between modes and bins. The simulations with the aerosol scheme, which considers the modal approach, show that the reduction of Nd across the SCT is driven by changes in the cloud liquid water content, the sulfate availability, and the fine sea-spray availability in the cumulus region, which suppresses sulfate activation. The Nd decreases mostly follow the decrease in accumulation-mode aerosols. For the scheme that considers the sectional approach, both the stratiform and the cumulus clouds appear sensitive to new particles formation and their competition for water. However, in the cumulus region, the higher updrafts and the greater availability of fine sea salt particles become critical for the activation of small particles. New particle formation and background sulfate concentrations are critical in this pristine environment, while sea salt particles have a significant impact on SCT in both sets of simulations.

Cold air outbreaks (CAOs) are phenomena that occur across high latitudes during winter months and favor the development of extensive boundary layer clouds. As the boundary layer evolves, changes in cloud morphology often result in a stratocumulus to cumulus transition (SCT). The onset of precipitation is considered to be a key factor that leads to the break-up of the stratocumulus deck. In this modeling study we investigate the additional role that aerosols have on the SCT within a CAO event in the North Atlantic, by using prognostic fields for both aerosols and cloud droplet number concentrations (Nd). By using two chemical/aerosol schemes we assess and quantify the impact of aerosols on the SCT evolution. Our results indicate that the aerosol load and its chemical composition affect the timing of precipitation initiation and its magnitude and thus the break-up. However, the two schemes reveal contradictory results, which are mainly associated with different aerosol size and chemical composition partitioning between modes and bins. The simulations with the aerosol scheme, which considers the modal approach, show that the reduction of Nd across the SCT is driven by changes in the cloud liquid water content, the sulfate availability, and the fine sea-spray availability in the cumulus region, which suppresses sulfate activation. The Nd decreases mostly follow the decrease in accumulation-mode aerosols. For the scheme that considers the sectional approach, both the stratiform and the cumulus clouds appear sensitive to new particles formation and their competition for water. However, in the cumulus region, the higher updrafts and the greater availability of fine sea salt particles become critical for the activation of small particles. New particle formation and background sulfate concentrations are critical in this pristine environment, while sea salt particles have a significant impact on SCT in both sets of simulations.

Η έμφυλη ισότητα στο πρωτοποριακό πανεπιστήμιο: Δημόσιος απολογισμός-προγραμματισμός δράσεων της ΕΙΦΚΔ του ΕΚΠΑ https://hub.uoa.gr/i-emfyli-isotita-sto-protoporiako-panepistimio-dimosios-apologismos-programmatismos-draseon-tis-eifkd-tou-ekpa-2/      ****Επίσης, βλέπε εισήγηση Ειρήνης Καμπερίδου με θέμα Ο ΕΜΦΥΛΟ ΧΑΡΤΗΣ ΣΤΟ ΕΚΠΑ στην εκδήλωση «Η έμφυλη ισότητα στο πρωτοποριακό πανεπιστήμιο»: Δημόσιος απολογισμός-προγραμματισμός δράσεων της Επιτροπής Ισότητας των Φύλων και Καταπολέμησης των Διακρίσεων (ΕΙΦΚΔ) του ΕΚΠΑ, σελ. 1-53. Αμφιθέατρο «Ιωάννης Δρακόπουλος», ΕΚΠΑ: https://pergamos.lib.uoa.gr/uoa/dl/object/3464920/file.pdf   (Σύνδεσμος στο YouTube του ΕΚΠΑ: https://www.youtube.com/live/zTwzXlEoXt4 .

Social identity may be a late-modern concept, styling one’s station in life through art, however, was indeed a recognizable trait of the past. Alexandrian art is the product of a society mixed both ethnically and culturally, so much so that social framing in it appears to become an end in itself. Acknowledging the liminality of death, funerary painting, and especially funerary portraiture from the Ptolemaic world, describes and defines the individual according to a predetermined set of values that are meant to reconfirm the community’s ways of representing itself. Through a series of remarkable examples, the lecture will comment on the development of Alexandrian funerary painting as a way of discussing Ptolemaic art in its Hellenistic context.

If we wish to formulate an axiomatic truth-theory interpreting a modal language and treat the symbol of necessity as a sentential operator and not as a quantifier over possible worlds, there arise various problems. These are due partly to the fact that words could have meant something other than what they actually mean and partly to certain principles of modal metaphysics. One of those principles is existentialism about propositions: a proposition that is expressed in a sentence containing a non-empty name could not exist if the referent of the name did not exist. The paper explains how the problems arise. It also explains how we can avoid them using substitutional quantification in the metalanguage. The truth-theory we can construct in that way is compositional and homophonic, and its theorems interpreting the various sentences of the modal language are derived in a straightforward way. The paper develops one such theory for a propositional modal language and one for a first-order modal language. The first-order case involves a number of intricacies that are discussed.

Neurodynamics is recognized as a powerful tool for addressing various problems in engineering, control, and intelligent systems. Over the past decade, neurodynamics-based methods and models have been rapidly developed, particularly in emerging areas such as neural computation and multi-agent systems. In this paper, we provide a brief survey of neurodynamics applied to computation and multi-agent systems. Specifically, we highlight key models and approaches related to time-varying computation, as well as cooperative and competitive behaviors in multi-agent systems. Furthermore, we discuss current challenges, potential opportunities, and promising future directions in this evolving field.

The synthesis and characterisation of two square planar {PdNO}10 pincer complexes of the form [Pd(pincer)(NO)]+ (pincer = 2,6-(tBu2PCH2)2C5H3N, 1; 2,6-(tBu2PO)2C5H3N, 2) are reported. These complexes are readily isolated by phosphine substitution of T-shaped [Pd(PtBu3)2(NO)]+ 3 in THF and the bent nitrosyl coordination mode observed in 3 is retained, as evidenced by X-ray diffraction (∠PdNO ∼ 120°), IR spectroscopy and analysis of isotopically enriched samples by 15N NMR spectroscopy. Effective oxidation states of Pd0/NO+ are calculated for 1–3 and nitrosyl coordination is principally attributed to metal-centred σ-bonding, with supplementary π-backbonding. Computational analysis, however, indicates that the Pd−NO bonds in 1 and 2 have greater PdI/NO• character and σ-bonding is more prominent than in 3. These differences in bonding are manifested experimentally in more red-shifted nitrosyl stretching frequencies and the propensity of 1 and 2 to react with dichloromethane to afford palladium(II) chloride derivatives.

We report on the preparation, crystal structure and spectral properties of the novel trimethylsulfonium tin tribromide, [(CH3)3S]SnBr3. The compound was synthesized by the solid-state reaction of (CH3)3SBr and SnBr2 in evacuated pyrex tubes at 150 °C. Single-crystal X-ray diffraction (SCXRD) studies at −173.15 °C show that it forms a 0D network of isolated pyramids of [SnBr3]− and (CH3)3S+ units in an orthorhombic structure (space group P212121, No. 19, a = 9.4508(8) Å, b = 14.1691(12) Å, c = 15.4409(14) Å)). Powder X-ray diffraction (PXRD) and Le bail profile fit analysis reveals that [(CH3)3S]SnBr3 adopts at room temperature a different crystal structure with space group (Pmmm, No. 47). Moreover, the oxidation of the compound occurs gradually in ambient air, towards the formation of [(CH3)3S)]2SnBr6 (space group Pa-3, No. 205). Multi-temperature Raman spectroscopy reveals that a fully reversible structural phase transition occurs for [(CH3)3S]SnBr3 between −36 and −56 °C, as evidenced by the changes in the vibrational modes of the [SnBr3]− ions. A direct band gap of 3.38 eV at RT is determined via UV–vis diffuse reflectance spectroscopy. Photoluminescence spectroscopy at −196.15 °C and 25 °C shows a weak luminescence signal with an emission maximum at ca. 460 nm for both temperatures.

Integrating plasmonic nanoparticles (NPs) into semiconductor metal oxides and structuring them as photonic crystals have been two effective strategies to develop robust photo(electro)catalysts with improved light harvesting and suppressed electron–hole recombination. In this work{,} Au-decorated WO3 inverse opal photoanodes were engineered to synergistically exploit plasmonic{,} photonic{,} and charge transfer effects for enhanced photoelectrochemical water splitting and the degradation of pharmaceutical pollutants. The WO3 inverse opal scaffolds{,} fabricated via colloidal co-assembly{,} functioned as visible light photonic crystals{,} enabling slow photon effects by aligning their photonic band gap with the absorption edge of WO3 and the localized surface plasmon resonance (LSPR) of Au NPs. Au NPs of varying sizes (5–80 nm) were incorporated post-synthetically to tailor plasmonic behavior and band alignment at the Au–WO3 metal–semiconductor heterojunction. Photoelectrochemical measurements revealed optimal photocurrent generation for 20 nm Au NPs{,} driven by near-field enhancement and improved carrier generation{,} while 5 nm Au NPs exhibited the highest photoelectrocatalytic activity in ibuprofen degradation{,} facilitated by a favorable Fermi level shift and efficient interfacial electron transfer. This work highlights the importance of size-engineered plasmonic particles integrated into photonic crystal frameworks for the rational design of multifunctional photoelectrodes in solar energy conversion and environmental remediation.

Existing research has shown that emotional intelligence (EI) and teacher self-efficacy (TSE) play an important role in the work of in-service teachers. However, there is limited research on these variables and their associations among pre-service teachers. Also, the cultural context is expected to influence EI and TSE. Therefore, this study examined the associations between EI and TSE in two cultures, Finland and Greece. A comprehensive evaluation of EI was done by including both trait EI and ability EI measures. Data from primary education student teachers from Finland (N = 82) and Greece (N = 117) were collected online. The measures of EI and TSE exhibited full configural and metric measurement invariance and partial scalar and residual/strict measurement invariance across cultures. Finnish students had significantly higher scores on all EI variables than Greek students, whereas Greek students scored higher on self-efficacy for student engagement. Structural equation modelling showed that trait EI was moderately associated with one facet of ability EI, namely emotional management, but not with emotional understanding, implying that trait EI and ability EI can be considered as partially distinct constructs. A statistically significant positive association between trait EI and TSE was found in Finland, whereas a statistically significant negative association between ability EI and TSE was found in Greece. The findings have important implications for the models of trait and ability EI, for understanding the links between trait and ability EI and TSE during the critical phase of teacher education in the two cultural contexts studied, and for culturally informed teacher education.

In this study, we considered teachers' emotion regulation and teaching-related anger as a combined construct with multiple manifestations on classroom management practices. Four hundred and five Greek in-service teachers (Mage = 44.55, SD = 10.13; age range = 21.0, 68.0 years) participated in a cross-sectional online survey who reported their ability to regulate their own emotions, their teaching-related anger and, both, dominant and collaborative approaches in classroom management practices. Latent Profile Analysis revealed an insufficiently regulated teacher profile with low emotion regulation and high anger, an adequately regulated teacher profile with medium levels of both emotion regulation and anger, and a teacher profile labelled as sufficiently regulated, with high emotion regulation and low anger. Although the teachers in the three groups did not differ in dominant practices, the teachers in the sufficiently regulated group reported higher collaborative practices than their counterparts in the other two groups. The results indicate that teachers with high emotion regulation and low anger favour collaboration, as they are better equipped to handle unexpected events that arise from active student interactions. Our findings underscore the key role of adaptive emotion regulation practices to promote collaborative learning in the classroom. © 2025 The Author(s). European Journal of Education published by John Wiley & Sons Ltd.

Thuwalamides A–E (1, 3, 5, 6 and 8), previously undescribed polychlorinated amides, along with ten previously reported related compounds (2, 4, 7 and 9–15), were isolated from the organic extract of the marine sponge Lamellodysidea herbacea (Keller), collected off the village of Thuwal in the Red Sea at Saudi Arabia. The structures of the isolated compounds have been determined through extensive analysis of their NMR and MS data, while their absolute stereochemistry was unequivocally established via single crystal X-ray diffraction. Additionally, the absolute stereochemistry of the previously reported compounds 2 and 4, whose configuration was not determined, has also been established using single-crystal X-ray crystallographic analysis. The antibacterial activity of compounds 1–15 was evaluated against Escherichia coli and Staphylococcus aureus. Among them, compound 14 displayed activity against S. aureus comparable to vancomycin that was used as a positive control with a MIC value of 4 μg/mL.

Topological rainbow trapping (TRT) arises from the interplay between topological states and frequency-dependent slow-wave effects. Waves first slow down, then become spatially separated by frequency and are ultimately trapped at distinct locations. TRT designs have been primarily explored in the context of photonic crystals and subsequently extended to acoustic and elastic systems. This emerging TRT concept enables robust, frequency-selective localization beyond conventional rainbow trapping, supporting compact, multi-wavelength, topologically protected platforms for extreme wave manipulation. In this Review, we elucidate the fundamental principles of TRT, emphasizing the physical mechanisms that create near-zero group velocity points with robust frequency-dependent localization. We highlight three key TRT mechanisms: graded index profiles, which gradually vary material parameters to reshape dispersion and induce slow-wave effects; higher-order topological corner modes, which exploit localized corner states for robust frequency-specific wave confinement; and synthetic dimensions, which expand the parameter space of the system to engineer stable interface states at distinct frequencies. Furthermore, we address key challenges in TRT, such as energy dissipation and tunability, while highlighting its broad range of potential applications. Finally, we discuss emerging research directions for TRT.

Mitochondrial dysfunction and impaired mitophagy are hallmarks of ageing and age-related pathologies. Disrupted inter-organellar communication among mitochondria, endoplasmic reticulum (ER), and lysosomes, further contributes to cellular dysfunction. While mitophagy has emerged as a promising target for neuroprotection and geroprotection, its potential to restore age-associated defects in organellar crosstalk remains unclear. Here, we show that mitophagy deficiency deregulates the morphology and homeostasis of mitochondria, ER and lysosomes, mirroring age-related alterations. In contrast, Urolithin A (UA), a gut-derived metabolite and potent mitophagy inducer, restores inter-organellar communication via calcium signaling, thereby, promoting mitophagy, healthspan and longevity. Our multi-omic analysis reveals that UA reorganizes ER, mitochondrial and lysosomal networks, linking inter-organellar dynamics to mitochondrial quality control. In Caenorhabditis elegans, UA induces calcium release from the ER, enhances lysosomal activity, and drives DRP-1/DNM1L/DRP1-mediated mitochondrial fission, culminating in efficient mitophagy. Calcium chelation abolishes UA-induced mitophagy, blocking its beneficial impact on muscle function and lifespan, underscoring the critical role of calcium signaling in UA's geroprotective effects. Furthermore, UA-induced calcium elevation activates mitochondrial biogenesis via UNC-43/CAMK2D and SKN-1/NFE2L2/Nrf2 pathways, which are both essential for healthspan and lifespan extension. Similarly, in mammalian cells, UA increases intracellular calcium, enhances mitophagy and mitochondrial metabolism, and mitigates stress-induced senescence in a calcium-dependent manner. Our findings uncover a conserved mechanism by which UA-induced mitophagy restores inter-organellar communication, supporting cellular homeostasis and organismal health.Abbreviations: Ca(2+): calcium ions; BJ: human foreskin fibroblasts; BNIP3: BCL2 interacting protein 3; BP: bipyridyl; CAMK2D: calcium/calmodulin dependent protein kinase II delta; CCCP: carbonyl cyanide m-chlorophenyl hydrazone; DEGs: differentially expressed genes; DEPs : differentially expressed peptides; DFP: deferiprone; DNM1L/DRP1: dynamin 1 like; EGTA: ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid; EMC: endoplasmic reticulum membrane protein complex; ER: endoplasmic reticulum; FCCP: carbonyl cyanide p-trifluoro-methoxyphenyl hydrazone; GO: gene ontology; GSVA: Gene Set Variation Analysis; HUVECs: human umbilical vein endothelial cells; IMM: inner mitochondrial membrane; ITPR/InsP3R: inositol 1,4,5-triphosphate receptor; MAM: mitochondria-associated ER membrane; MAPK: mitogen-activated protein kinase; MCU: mitochondrial calcium uniporter; MEFs: mouse embryonic fibroblasts; NAC : N-acetylcysteine; NFE2L2/Nrf2: NFE2 like bZIP transcription factor 2; NMN: nicotinamide mononucleotide; NR: nicotinamide riboside; OMM: outer mitochondrial membrane; PCA: principal-component analysis; PPARGC1A/PGC1α: PPARG coactivator 1 alpha; PQ: paraquat; TMCO: transmembrane and coiled-coil domains 1; TMRE: tetramethylrhodamine ethyl ester perchlorate; UA: urolithin A; VDAC: voltage dependent anion channel.

Wine matrix is composed of a vast number of compounds that depend on a wide range of factors associated with the raw material, such as grape variety and vineyard location, and processing, such as the winemaking protocol and barrel ageing. Monitoring all aspects of winemaking from grape to wine is a technically challenging task, as different key compounds are related to each step, requiring different analytical methods for their estimation. Nowadays, efforts are made to avoid the use of chemical reagents that can be harmful to the environment and lower the energy consumption during chemical analyses. Ideally, analyses should be performed using a single instrument, without the need for solvents or lengthy preparatory steps. In the past few years, due to its cost-effectiveness and the speediness of the analyses while using low sample volumes, IR spectroscopy has been effectively applied in grape and wine analyses, from compound identification and quantification to wine profile characterisation and authentication. One of its most advantageous features is that it can produce a spectral fingerprint that is unique to each sample, making it highly efficient, especially for authentication purposes. This review examines the feasibility of employing IR spectroscopy for the assessment of all steps required in winemaking, from grape to wine, and its ability to produce integrated results.

Extreme weather events, increasingly frequent in the Mediterranean due to climate change, pose significant risks by triggering hydrogeomorphic processes such as slope failures. These phenomena, particularly prevalent in tectonically active and steeply sloped coastal areas, present challenges for monitoring due to their spatial and temporal dynamics.Unmanned aerial systems (UAS) and advanced photogrammetric techniques, including structure-from-motion (SfM) and multi-view stereo (MVS), have emerged as transformative tools for capturing high-resolution terrain data. This study employs UAS-aided photogrammetry alongside change detection methods, such as digital elevation models of differences (DoD) and cloud-to-cloud distance (C2C), to analyze geomorphic changes induced by extreme storms in highly visited and geologically dynamic coastal areas in Greece.The findings reveal the utility of UAS in providing detailed morphometric measurements, delineating areas of erosion and deposition, and identifying high-risk zones. These capabilities facilitate a deeper understanding of geomorphic processes, enabling informed risk assessment and management strategies. The study underscores the potential of integrating UAS and photogrammetry for continuous monitoring in regions with high socioeconomic and environmental value. This approach not only supports sustainable development by minimizing disruptions but also enhances safety standards in vulnerable, high-exposure coastal areas. Through this methodological framework, the research contributes to addressing the pressing need for resilient hazard management in the context of evolving climatic conditions.

Titanium dioxide (TiO2) is a benchmark photocatalyst for environmental applications, but its limited visible-light activity due to a wide band gap and fast charge recombination restricts its practical efficiency. This study presents the development of heterostructured Ag (Au)/MoS2-TiO2 inverse opal (IO) films that synergistically integrate photonic, plasmonic, and semiconducting functionalities to overcome these limitations. The materials were synthesized via a one-step evaporation-induced co-assembly approach, embedding MoS2 nanosheets and plasmonic nanoparticles (Ag or Au) within a nanocrystalline TiO2 photonic framework. The inverse opal architecture enhances light harvesting through slow-photon effects, while MoS2 and plasmonic nanoparticles improve visible-light absorption and charge separation. By tuning the template sphere size, the photonic band gap was aligned with the TiO2-MoS2 absorption edge and the localized surface plasmon resonance of Ag, enabling optimal spectral overlap. The corresponding Ag/MoS2-TiO2 photonic films exhibited superior photocatalytic and photoelectrocatalytic degradation of tetracycline under visible light. Ultraviolet photoelectron spectroscopy and Mott–Schottky analysis confirmed favorable band alignment and Fermi level shifts that facilitate interfacial charge transfer. These results highlight the potential of integrated photonic–plasmonic-semiconductor architectures for efficient solar-driven water treatment.

En las últimas décadas se han desarrollado numerosas herramientas digitales, algunas de las cuales se han orientado a la investigación lingüística. Este estudio presenta tres herramientas informáticas: Dispografo, Gephi y Lexpro, utilizadas para el apoyo del análisis psicolingüístico del léxico disponible. Estas herramientas representan asociaciones léxicas en el lexicón mental mediante la teoría de grafos, a las cuales tenemos acceso a través de la prueba de disponibilidad léxica. Se profundiza en los conceptos de disponibilidad léxica, red semántica y grafos léxicos, fundamentales para el análisis y visualización de relaciones léxicas. Además, se examina la función de estas herramientas y se muestran ejemplos de grafos generados en diversos estudios con Dispografo, Gephi y Lexpro. Los análisis revelan que estas herramientas permiten visualizar las complejas relaciones léxicas del lexicón mental y facilitan un análisis profundo, contribuyendo a una mejor comprensión de dichas relaciones. Su uso demuestra ser valioso para el estudio de la estructura y organización del léxico. Finalmente, se exploran las aplicaciones pedagógicas de los grafos léxicos en la enseñanza de lenguas extranjeras y sus posibles desarrollos futuros a través de inteligencia artificial y procesamiento del lenguaje natural.

Abstract An isotype heterojunction n+-ZnO/n-Si photodetector is developed, showing adjustable wavelength-selective operation at self-powered conditions. Without an external bias voltage, the device can operate either as a broadband UV–vis–NIR or as a NIR-only photodetector, depending on the relative carrier concentrations of ZnO and silicon. In addition, the photodetector can be tuned to either broadband or NIR operation by the application of an external bias voltage, regardless of carrier concentrations. At negative bias, it demonstrates UV–vis–NIR photodetection, while at positive bias, NIR photodetection. Photovoltage and photocurrent measurements for pulsed illumination reveal a high-speed self-powered response, with rise and fall times <100 µs across the UV–vis–NIR. The device can be engineered to reproduce undistorted pulsed light with frequencies as high as 1 kHz. Self-powered responsivity reaches ≈70 mA W−1, which becomes ≈4 A W−1 with an applied external bias.

BACKGROUND: Atrial fibrillation (AF) is the most common supraventricular arrhythmia and is associated with an impaired prognosis. Studies using implantable cardiac monitors suggest that this association is closely linked to AF burden, defined as the percentage of time spent in AF. Consequently, there is a growing need for affordable and comfortable alternative devices, such as wearables, capable of reliably monitoring AF burden in patients with AF. METHODS: Major electronic databases were searched for studies comparing AF burden quantification using wearables and reference ECG monitoring methods. A Bayesian approach was adopted for the final analysis. RESULTS: Six studies, including a total of 448 patients and 36,978 h of valid simultaneous recordings, were analyzed. Bayesian analysis revealed no statistically significant differences between wearables and reference methods in AF burden quantification. The mean error was 1% (95% CrIs: -4% to 7%). Similar findings were observed in the subgroup analysis of studies assessing only smartwatches. Between-study heterogeneity was low, and no evidence of publication bias was detected. CONCLUSION: Our analysis suggests that AF burden quantification using wearables is comparable to reference ECG monitoring methods. These findings support the potential role of wearables in clinical practice, particularly for research and prognostic purposes. However, more studies are needed to determine whether the observed statistical equivalence translates to clinical significance, thereby supporting the widespread use of wearables in the assessment of rhythm control therapeutic strategies.

This study presents and evaluates interpretations of 2 Thess 2:3-12 from a critical-Orthodox perspective in the Greek commentaries of Severian of Gabala, John Chrysostom, Theodoret of Cyrus, John of Damascus (dubium), and Theophylact of Ohrid. The patristic comments elaborate on the nature, actions, and unique connection between the Antichrist and the devil, as well as the significance of “the restrainer”, which prevents the Antichrist’s arrival. The commentaries also thoroughly discuss the concept of the “mystery of lawlessness”, the responsibility and condemnation of those who will believe in the Antichrist, and his ultimate defeat by the Lord Jesus Christ at his second coming. In conclusion, the study finds that the patristic commentators, by extensively referring to the Antichrist, essentially describe the nature of evil – personified by the figure of the Antichrist – and the way to address it. According to this conclusion, evil primarily consists in human self-deification and simultaneous estrangement from communion with God. Evil must be overcome with good; thus, through faith in God, abstaining from all forms of aggression, and practicing love for one’s fellow human beings.

Kamberidou, Irene (2025). Women’s Agency and Entrepreneurship in the Digital Age.  Presentation in Session V, "Entrepreneurship, Education, and Gender Dynamics" at the ICAEB & ICSTM 2025: the 9th International Conference on Applied Economics and Business (ICAEB 2025) and the 9th International Conference on Sustainable Tourism Management (ICSTM 2025), August 24-26, 2025 Paris, France. DOI: 10.13140/RG.2.2.19976.28167. Available in PERGAMOS:  https://pergamos.lib.uoa.gr/mypergamos/scientific-publications/edit/uoadl:5303794  

The paper is an attempt to constructively use the differences between Science, led by Physics, on one hand and Biology on the other. More specifically, the common framework of STEM teaching is encouraged as a teaching tool for teaching concepts related to the epistemology of the two disciplines, through their epistemological differences. As such disparities, the following are proposed: The existence of a unifying theory in their teaching, and the absence of "universal" laws in Biology. Furthermore, the dissimilar roles played among them by the experiment, mathematics and history. In addition, it is commended the difference in the meanings of the concepts "Social Implications" and "Social Science", together with the meaning of the essentialism in Physics, as opposed to the non-typological "population perspective" in Biology, where the endless, random errors and deviations (mutations) are the universal driving force, that prevails behind all biological phenomena.

Βέδες, Μπράχμανας, Αράνυακας, Ουπανισάδες, Γκρίχυα Σούτρας, Ντάρμα Σούτρας, Ντάρμα Σάστρας, Μαχά-μπάρατα, Ραμάγιανα, Πουράνας κ.τ.λ. Πώς αποτυπώνεται η θέση της γυναίκας στην ινδουιστική γραμματεία; Ποια είναι η θέση της κατά την ιστορική πορεία εξέλιξης του Ινδουισμού; Από ποιες φάσεις εξέλιξης πέρασε η θέση της στην Ινδία, στη χώρα όπου γεννήθηκε ο Ινδουισμός και σήμερα είναι συγκεντρώνει τον μεγαλύτερο όγκο του παγκόσμιου ινδουιστικού πληθυσμού; Ποιες ήταν οι απόψεις των κοινωνικών μεταρρυθμιστών του 19ου αιώνα και του Μαχάτμα Γκάντι για το γυναικείο φύλο; Ποιες είναι οι απόψεις του ινδικού φεμινιστικού κινήματος; Ποια είναι η θέση της ως κόρη, σύζυγος, μητέρα, χήρα, ασκήτρια, θεά κατά το ιστορικό διάβα του Ινδουισμού; Πώς νοείται η γυναικεία φύση και ποιες ηθικές και κανονιστικές παράμετροι συνδέονται με τις βιολογικές λειτουργίες του γυναικείου σώματος; Αυτά και άλλα ερωτήματα εξετάζει η παρούσα μελέτη από θρησκειολογική σκοπιά, λαμβάνοντας υπ’ όψιν ιστορικές, κοινωνιολογικές, ψυχολογικές και κοινωνικοπολιτικές παραμέτρους. Μια μελέτη που απευθύνεται όχι μόνο σε θρησκειολόγους, αλλά σε κάθε ενδιαφερόμενο.

Έχει φύλο η επιχειρηματικότητα; Συνεχίζεται η έμφυλη κόπωση στον εργασιακό χώρο; Πώς διαχειρίζονται και τροποποιούν τα αναχρονιστικά στερεότυπα στον τομέα της επιχειρηματικότητας οι γυναίκες του 21ου αιώνα; Τι είδους γνώσεις και δεξιότητες απαιτούνται στον ψηφιακό κόσμο σήμερα για επαγγελματική εξέλιξη και επιτυχία στο επιχειρείν; Ερευνητικά δεδομένα με θέμα τη γυναίκα, το φύλο, την επιχειρηματικότητα και την ηγεσία (1974–2024) επιβεβαιώνουν ότι δεν έχουν αλλάξει πολλά. Παρά την πρόοδο που έχει σημειωθεί στην αναγνώριση των καινοτομιών και συνεισφορών των γυναικών στον τομέα της επιχειρηματικότητας, οι γυναίκες επιχειρηματίες υποεκπροσωπούνται παγκοσμίως. Οι γυάλινες οροφές δεν έχουν θρυμματιστεί ακόμα.  Ερευνητικά στοιχεία του 21ου αιώνα -όπως και εκείνα του 20ού- εντοπίζουν ότι το έμφυλο χάσμα στην επιχειρηματικότητα προκύπτει εξαιτίας των έμφυλων διακρίσεων/στερεότυπων, της έλλειψης δεξιοτήτων μάρκετινγκ, διαθεσιμότητας οικονομικών πόρων και υπηρεσιών υποστήριξης,  συμπεριλαμβανομένης της κακής πρόσβασης σε επιχειρηματικά δίκτυα, ακόμα και στο αναπτυσσόμενο-νέο ψηφιακό τοπίο. Τα ίδια ερωτήματα διερευνώνται σήμερα, καθώς οι έμφυλες διακρίσεις— που τώρα συμπεριλαμβάνουν και το ψηφιακό χάσμα—εξακολουθούν να υπάρχουν.  Επιπροσθέτως, μολονότι οι ανεπτυγμένες και αναπτυσσόμενες χώρες αναγνωρίζουν ότι οι επιχειρηματικές δραστηριότητες των γυναικών συμβάλλουν στην κοινωνικοοικονομική ανάπτυξη και βιωσιμότητα, «η δίνη των πολλαπλών υποχρεώσεων/εργασιών» (multitasking whirlpool) εξακολουθεί να οδηγεί στην έμφυλη κόπωση, υποδεικνύοντας ότι έχουμε ακόμη πολύ δρόμο να διανύσουμε, ειδικά  στις αναπτυσσόμενες οικονομίες. Αυτή η μελέτη επιδιώκει να απαντήσει στο ακόλουθο ερευνητικό ερώτημα: Μεταβάλλονται οι αντιλήψεις για την επαγγελματική επιτυχία τον 21ο αιώνα; Ο στόχος είναι να αναδειχθεί το είδος των γνώσεων και δεξιοτήτων που απαιτούνται στο ψηφιακό τοπίο και να εντοπισθούν τα χαρακτηριστικά μιας επιτυχημένης επιχειρηματία. Μελλοντικές κατευθύνσεις: να ρίξουμε λίγο φως σε γυναίκες-πρότυπα που διαπρέπουν στον κόσμο των startups (νεοφυείς επιχειρήσεις), στη γαλάζια οικονομία και στην αργυρή οικονομία.****ΕΠΙΣΗΣ ΒΛΕΠΕ ΜΟΝΙΜΗ ΔΙΕΥΘΥΝΣΗ  ΣΤΗΝ ΠΕΡΓΑΜΟ (PERGAMOS) ΤΟΥ ΕΚΠΑ:https://pergamos.lib.uoa.gr/uoa/dl/object/3473838