An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT1 Angiotensin II receptor antagonist: Reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies

Citation:

Agelis, G. ; Roumelioti, P. ; Resvani, A. ; Durdagi, S. ; Androutsou, M. - E. ; Kelaidonis, K. ; Vlahakos, D. ; Mavromoustakos, T. ; Matsoukas, J. An Efficient Synthesis Of A Rationally Designed 1,5 Disubstituted Imidazole At1 Angiotensin Ii Receptor Antagonist: Reorientation Of Imidazole Pharmacophore Groups In Losartan Reserves High Receptor Affinity And Confirms Docking Studies. Journal of Computer-Aided Molecular Design 2010, 24, 749 - 758.

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Cited By :12Export Date: 23 August 2017

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