Publications

2018
Mirza, S. B. ; Lee, R. C. H. ; Chu, J. J. H. ; Salmas, R. E. ; Mavromoustakos, T. ; Durdagi, S. Discovery Of Selective Dengue Virus Inhibitors Using Combination Of Molecular Fingerprint-Based Virtual Screening Protocols, Structure-Based Pharmacophore Model Development, Molecular Dynamics Simulations And In Vitro Studies. Journal of Molecular Graphics and Modelling 2018, 79, 88 - 102. Website
2017
Liapakis, G. ; Matsoukas, M. - T. ; Karageorgos, V. ; Venihaki, M. ; Mavromoustakos, T. Family B G Protein-Coupled Receptors And Their Ligands: From Structure To Function. Current Medicinal Chemistry 2017, 24, 3323 - 3355. Website
Kellici, T. F. ; Chatziathanasiadou, M. V. ; Lee, M. - S. ; Sayyad, N. ; Geromichalou, E. G. ; Vrettos, E. I. ; Tsiailanis, A. D. ; Chi, S. - W. ; Geromichalos, G. D. ; Mavromoustakos, T. ; et al. Rational Design And Structure-Activity Relationship Studies Of Quercetin-Amino Acid Hybrids Targeting The Anti-Apoptotic Protein Bcl-Xl. Organic and Biomolecular Chemistry 2017, 15, 7956 - 7976. Website
Vrettos, E. I. ; Sayyad, N. ; Mavrogiannaki, E. M. ; Stylos, E. ; Kostagianni, A. D. ; Papas, S. ; Mavromoustakos, T. ; Theodorou, V. ; Tzakos, A. G. Unveiling And Tackling Guanidinium Peptide Coupling Reagent Side Reactions Towards The Development Of Peptide-Drug Conjugates. RSC Advances 2017, 7, 50519 - 50526. Website
Vrontaki, E. ; Melagraki, G. ; Voskou, S. ; Phylactides, M. S. ; Mavromoustakos, T. ; Kleanthous, M. ; Afantitis, A. Development Of A Predictive Pharmacophore Model And A 3D-Qsar Study For An In Silico Screening Of New Potent Bcr-Abl Kinase Inhibit. Mini-Reviews in Medicinal Chemistry 2017, 17, 188 - 204. Website
Vrontaki, E. ; Mavromoustakos, T. ; Melagraki, G. ; Afantitis, A. Quantitative Nanostructure-Activity Relationship Models For The Risk Assessment Of Nanomaterials. In Materials Science and Engineering: Concepts, Methodologies, Tools, and Applications; 2017; Vol. 1-3, pp. 20 - 44. Website
Vrontaki, E. ; Melagraki, G. ; Afantitis, A. ; Mavromoustakos, T. ; Kollias, G. Searching For Novel Janus Kinase-2 Inhibitors Using A Combination Of Pharmacophore Modeling, 3D-Qsar Studies And Virtual Screening. Mini-Reviews in Medicinal Chemistry 2017, 17, 268 - 294. Website
Melagraki, G. ; Ntougkos, E. ; Rinotas, V. ; Papaneophytou, C. ; Leonis, G. ; Mavromoustakos, T. ; Kontopidis, G. ; Douni, E. ; Afantitis, A. ; Kollias, G. Cheminformatics-Aided Discovery Of Small-Molecule Protein-Protein Interaction (Ppi) Dual Inhibitors Of Tumor Necrosis Factor (Tnf) And Receptor Activator Of Nf-Κb Ligand (Rankl). PLoS Computational Biology 2017, 13. Website
Ntountaniotis, D. ; Vanioti, Μ. ; Kordopati, G. G. ; Kellici, T. F. ; Marousis, K. D. ; Mavromoustakos, T. ; Spyroulias, G. A. ; Golic Grdadolnik, S. ; Tselios, T. V. A Combined Nmr And Molecular Dynamics Simulation Study To Determine The Conformational Properties Of Rat/mouse 35-55 Myelin Oligodendrocyte Glycoprotein Epitope Implicated In The Induction Of Experimental Autoimmune Encephalomyelitis. Journal of Biomolecular Structure and Dynamics 2017, 35, 1559 - 1567. Website
Chatzigeorgiou, P. ; Mourelatou, A. ; Pollatos, E. ; Margari, D. ; Zogzas, N. ; Viras, K. ; Mavromoustakos, T. ; Semidalas, C. E. Comparison Of The Thermal Behavior And Conformational Changes In Partially And Fully Hydrated Dipalmitoylphosphatidylcholine Systems. Journal of Thermal Analysis and Calorimetry, 2017, 1 - 12. Website
Raptopoulos, G. ; Kyriakou, K. ; Mali, G. ; Scarpellini, A. ; Anyfantis, G. C. ; Mavromoustakos, T. ; Pitsikalis, M. ; Paraskevopoulou, P. Copolymerization Of Norbornene And Norbornadiene Using A Cis-Selective Bimetallic W-Based Catalytic System. Polymers 2017, 9. Website
Kellici, T. F. ; Mavromoustakos, T. ; Jendrossek, D. ; Papageorgiou, A. C. Crystal Structure Analysis, Covalent Docking, And Molecular Dynamics Calculations Reveal A Conformational Switch In Phaz7 Phb Depolymerase. Proteins: Structure, Function and Bioinformatics 2017, 85, 1351 - 1361. Website
Liossi, A. S. ; Ntountaniotis, D. ; Kellici, T. F. ; Chatziathanasiadou, M. V. ; Megariotis, G. ; Mania, M. ; Becker-Baldus, J. ; Kriechbaum, M. ; Krajnc, A. ; Christodoulou, E. ; et al. Exploring The Interactions Of Irbesartan And Irbesartan–2-Hydroxypropyl-Β-Cyclodextrin Complex With Model Membranes. Biochimica et Biophysica Acta - Biomembranes 2017, 1859, 1089 - 1098. Website
Vlachou, M. ; Siamidi, A. ; Diamantidi, E. ; Iliopoulou, A. ; Papanastasiou, I. ; Ioannidou, V. ; Kourbeli, V. ; Foscolos, A. - S. ; Vocat, A. ; Cole, S. T. ; et al. In Vitro Controlled Release From Solid Pharmaceutical Formulations Of Two New Adamantane Aminoethers With Antitubercular Activity (I). Drug Research 2017, 67, 447 - 450. Website
Vlachou, M. ; Siamidi, A. ; Spaneas, D. ; Lentzos, D. ; Ladia, P. ; Anastasiou, K. ; Papanastasiou, I. ; Foscolos, A. - S. ; Georgiadis, M. - O. ; Karalis, V. ; et al. In Vitro Controlled Release Of Two New Tuberculocidal Adamantane Aminoethers From Solid Pharmaceutical Formulations (Ii). Drug Research, 2017. Website
Moschonas, I. C. ; Kellici, T. F. ; Mavromoustakos, T. ; Stathopoulos, P. ; Tsikaris, V. ; Magafa, V. ; Tzakos, A. G. ; Tselepis, A. D. Molecular Requirements Involving The Human Platelet Protease-Activated Receptor-4 Mechanism Of Activation By Peptide Analogues Of Its Tethered-Ligand. Platelets, 2017, 1 - 10. Website
Kellici, T. F. ; Ntountaniotis, D. ; Vanioti, M. ; Golic Grdadolnik, S. ; Simcic, M. ; Michas, G. ; Moutevelis-Minakakis, P. ; Mavromoustakos, T. The Use Of J-Coupling As A Sole Criterion To Assign The Total Absolute Stereochemistry Of New Pyrrolidinone Class Synthetic Analogs, Derived From S-Pyroglutamic Acid. Journal of Molecular Structure 2017, 1129, 195 - 199. Website
2016
Goulas, V. ; Stylos, E. ; Chatziathanasiadou, M. V. ; Mavromoustakos, T. ; Tzakos, A. G. Functional Components Of Carob Fruit: Linking The Chemical And Biological Space. International Journal of Molecular Sciences 2016, 17. Website
Vrontaki, E. ; Mavromoustakos, T. ; Melagraki, G. ; Afantitis, A. Quantitative Nanostructure-Activity Relationship Models For The Risk Assessment Of Nanomaterials. In Pharmaceutical Sciences: Breakthroughs in Research and Practice; 2016; Vol. 2, pp. 1314 - 1338. Website
Vrontaki, E. ; Melagraki, G. ; Afantitis, A. ; Mavromoustakos, T. Beta-Thalassaemia And Therapeutic Approaches. Pharmakeftiki 2016, 28, 108 - 116. Website
Koukoulitsa, C. ; Villalonga-Barber, C. ; Csonka, R. ; Alexi, X. ; Leonis, G. ; Dellis, D. ; Hamelink, E. ; Belda, O. ; Steele, B. R. ; Micha-Screttas, M. ; et al. Biological And Computational Evaluation Of Resveratrol Inhibitors Against Alzheimers Disease. Journal of Enzyme Inhibition and Medicinal Chemistry 2016, 31, 67 - 77. Website
Karakurt, S. ; Kellici, T. F. ; Mavromoustakos, T. ; Tzakos, A. G. ; Yilmaz, M. Calixarenes In Lipase Biocatalysis And Cancer Therapy. Current Organic Chemistry 2016, 20, 1043 - 1057. Website
Vasilakaki, S. ; Barbayianni, E. ; Leonis, G. ; Papadopoulos, M. G. ; Mavromoustakos, T. ; Gelb, M. H. ; Kokotos, G. Development Of A Potent 2-Oxoamide Inhibitor Of Secreted Phospholipase A2 Guided By Molecular Docking Calculations And Molecular Dynamics Simulations. Bioorganic and Medicinal Chemistry 2016, 24, 1683 - 1695. Website
Kellici, T. F. ; Ntountaniotis, D. ; Kritsi, E. ; Zervou, M. ; Zoumpoulakis, P. ; Potamitis, C. ; Durdagi, S. ; Salmas, R. E. ; Ergun, G. ; Gokdemir, E. ; et al. Leveraging Nmr And X-Ray Data Of The Free Ligands To Build Better Drugs Targeting Angiotensin Ii Type 1 G-Protein Coupled Receptor. Current Medicinal Chemistry 2016, 23, 36 - 59. Website
Foscolos, A. - S. ; Papanastasiou, I. ; Foscolos, G. B. ; Tsotinis, A. ; Kellici, T. F. ; Mavromoustakos, T. ; Taylor, M. C. ; Kelly, J. M. New Hydrazones Of 5-Nitro-2-Furaldehyde With Adamantanealkanohydrazides: Synthesis And: In Vitro Trypanocidal Activity. MedChemComm 2016, 7, 1229 - 1236. Website
Vrontaki, E. ; Melagraki, G. ; Mavromoustakos, T. ; Afantitis, A. Searching For Anthranilic Acid-Based Thumb Pocket 2 Hcv Ns5B Polymerase Inhibitors Through A Combination Of Molecular Docking, 3D-Qsar And Virtual Screening. Journal of Enzyme Inhibition and Medicinal Chemistry 2016, 31, 38 - 52. Website
Vrontaki, E. ; Melagraki, G. ; Kaffe, E. ; Mavromoustakos, T. ; Kokotos, E. ; Aidinis, V. ; Afantitis, A. Computer Aided Drug Design Approaches For Identification Of Novel Autotaxin (Atx) Inhibitors. Current Medicinal Chemistry 2016, 23, 1708 - 1724. Website
Kontogianni, V. G. ; Tsoumani, M. E. ; Kellici, T. F. ; Mavromoustakos, T. ; Gerothanassis, I. P. ; Tselepis, A. D. ; Tzakos, A. G. Deconvoluting The Dual Antiplatelet Activity Of A Plant Extract. Journal of Agricultural and Food Chemistry 2016, 64, 4511 - 4521. Website
Kellici, T. F. ; Ntountaniotis, D. ; Liapakis, G. ; Tzakos, A. G. ; Mavromoustakos, T. The Dynamic Properties Of Angiotensin Ii Type 1 Receptor Inverse Agonists In Solution And In The Receptor Site. Arabian Journal of Chemistry, 2016. Website
Kritsi, E. ; Matsoukas, M. - T. ; Potamitis, C. ; Karageorgos, V. ; Detsi, A. ; Magafa, V. ; Liapakis, G. ; Mavromoustakos, T. ; Zoumpoulakis, P. Exploring New Scaffolds For Angiotensin Ii Receptor Antagonism. Bioorganic and Medicinal Chemistry 2016, 24, 4444 - 4451. Website
Goulas, V. ; Stylos, E. ; Chatziathanasiadou, M. V. ; Mavromoustakos, T. ; Tzakos, A. G. Functional Components Of Carob Fruit: Linking The Chemical And Biological Space. International Journal of Molecular Sciences 2016, 17. Website
Kellici, T. F. ; Chatziathanasiadou, M. V. ; Diamantis, D. ; Chatzikonstantinou, A. V. ; Andreadelis, I. ; Christodoulou, E. ; Valsami, G. ; Mavromoustakos, T. ; Tzakos, A. G. Mapping The Interactions And Bioactivity Of Quercetin—(2-Hydroxypropyl)-Β-Cyclodextrin Complex. International Journal of Pharmaceutics 2016, 511, 303 - 311. Website
Vrontaki, E. ; Mavromoustakos, T. ; Melagraki, G. ; Afantitis, A. Quantitative Nanostructure-Activity Relationship Models For The Risk Assessment Of Nanomaterials. In Pharmaceutical Sciences: Breakthroughs in Research and Practice; 2016; Vol. 2, pp. 1314 - 1338. Website
2015
Kollatos, N. ; Manta, S. ; Dimopoulou, A. ; Parmenopoulou, V. ; Triantakonstanti, V. V. ; Kellici, T. ; Mavromoustakos, T. ; Schols, D. ; Komiotis, D. Branched-Chain Sugar Nucleosides: Stereocontrolled Synthesis And Bioevaluation Of Novel 3′-C-Trifluoromethyl And 3′-C-Methyl Pyranonucleosides. Carbohydrate Research 2015, 407, 170 - 178. Website
Sadeghpour, A. ; Rappolt, M. ; Ntountaniotis, D. ; Chatzigeorgiou, P. ; Viras, K. ; Megariotis, G. ; Papadopoulos, M. G. ; Siapi, E. ; Mali, G. ; Mavromoustakos, T. Comparative Study Of Interactions Of Aliskiren And At<inf>1</inf> Receptor Antagonists With Lipid Bilayers. Biochimica et Biophysica Acta - Biomembranes 2015, 1848, 984 - 994. Website
Vrontaki, E. ; Melagraki, G. ; Mavromoustakos, T. ; Afantitis, A. Exploiting Chembl Database To Identify Indole Analogs As Hcv Replication Inhibitors. Methods 2015, 71, 4 - 13. Website
Kellici, T. F. ; Ntountaniotis, D. ; Leonis, G. ; Chatziathanasiadou, M. ; Chatzikonstantinou, A. V. ; Becker-Baldus, J. ; Glaubitz, C. ; Tzakos, A. G. ; Viras, K. ; Chatzigeorgiou, P. ; et al. Investigation Of The Interactions Of Silibinin With 2-Hydroxypropyl-Β-Cyclodextrin Through Biophysical Techniques And Computational Methods. Molecular Pharmaceutics 2015, 12, 954 - 965. Website
Kordopati, G. G. ; Tselios, T. V. ; Kellici, T. ; Merzel, F. ; Mavromoustakos, T. ; Grdadolnik, S. G. ; Tsivgoulis, G. M. A Novel Synthetic Luteinizing Hormone-Releasing Hormone (Lhrh) Analogue Coupled With Modified Β-Cyclodextrin: Insight Into Its Intramolecular Interactions. Biochimica et Biophysica Acta - General Subjects 2015, 1850, 159 - 168. Website
Vrontaki, E. ; Mavromoustakos, T. ; Melagraki, G. ; Afantitis, A. Quantitative Nanostructure-Activity Relationship Models For The Risk Assessment Of Nanomaterials. In Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment; 2015; pp. 535 - 559. Website
Kellici, T. F. ; Tzakos, A. G. ; Mavromoustakos, T. Rational Drug Design And Synthesis Of Molecules Targeting The Angiotensin Ii Type 1 And Type 2 Receptors. Molecules 2015, 20, 3868 - 3897. Website
Kellici, T. ; Ntountaniotis, D. ; Vrontaki, E. ; Liapakis, G. ; Moutevelis-Minakakis, P. ; Kokotos, G. ; Hadjikakou, S. ; Tzakos, A. G. ; Afantitis, A. ; Melagraki, G. ; et al. Rational Drug Design Paradigms: The Odyssey For Designing Better Drugs. Combinatorial Chemistry and High Throughput Screening 2015, 18, 238 - 256. Website
Vrontaki, E. ; Leonis, G. ; Avramopoulos, A. ; Papadopoulos, M. G. ; Simčič, M. ; Grdadolnik, S. G. ; Afantitis, A. ; Melagraki, G. ; Hadjikakou, S. K. ; Mavromoustakos, T. Stability And Binding Effects Of Silver(I) Complexes At Lipoxygenase-1. Journal of Enzyme Inhibition and Medicinal Chemistry 2015, 30, 539 - 549. Website
Vrontaki, E. ; Melagraki, G. ; Afantitis, A. ; Tsantili-Kakoulidou, A. ; Mavromoustakos, T. 3D Quantitative Structure - Activity Relationships (3D - Qsar): A Short Overview. Pharmakeftiki 2015, 27, 126 - 137. Website
Tzoupis, H. ; Leonis, G. ; Avramopoulos, A. ; Reis, H. ; Czyznikowska, Z. ; Zerva, S. ; Vergadou, N. ; Peristeras, L. D. ; Papavasileiou, K. D. ; Alexis, M. N. ; et al. Elucidation Of The Binding Mechanism Of Renin Using A Wide Array Of Computational Techniques And Biological Assays. Journal of Molecular Graphics and Modelling 2015, 62, 138 - 149. Website
Kellici, T. F. ; Liapakis, G. ; Tzakos, A. G. ; Mavromoustakos, T. Pharmaceutical Compositions For Antihypertensive Treatments: A Patent Review. Expert Opinion on Therapeutic Patents 2015, 25, 1305 - 1317. Website
2014
Mavromoustakos, T. ; Tsotinis, A. 32Nd Cyprus-Noordwijkerhout-Camerino Symposium: Trends In Drug Research 2014. ChemMedChem 2014, 9, 1903 - 1905. Website
Ntountaniotis, D. ; Kellici, T. ; Tzakos, A. ; Kolokotroni, P. ; Tselios, T. ; Becker-Baldus, J. ; Glaubitz, C. ; Lin, S. ; Makriyannis, A. ; Mavromoustakos, T. The Application Of Solid-State Nmr Spectroscopy To Study Candesartan Cilexetil (Tcv-116) Membrane Interactions. Comparative Study With The At1R Antagonist Drug Olmesartan. Biochimica et Biophysica Acta - Biomembranes 2014, 1838, 2439 - 2450. Website
Roulia, M. ; Mavromoustakos, T. ; Vassiliadis, A. A. ; Mali, G. Distinctive Spectral And Microscopic Features For Characterizing The Three-Dimensional Local Aluminosilicate Structure Of Perlites. Journal of Physical Chemistry C 2014, 118, 26649 - 26658. Website
Ntountaniotis, D. ; Agelis, G. ; Resvani, A. ; Halabalaki, M. ; Liapakis, G. ; Spyridaki, K. ; Golic Grdadolnik, S. ; Merzel, F. ; Kostidis, S. ; Potamitis, C. ; et al. An Efficient Synthetic Method And Theoretical Calculations Of Olmesartan Methyl Ether: Study Of Biological Function Of At1 Antagonism. Combinatorial Chemistry and High Throughput Screening 2014, 17, 642 - 662. Website
Zervou, M. ; Cournia, Z. ; Potamitis, C. ; Patargias, G. ; Durdagi, S. ; Grdadolnik, S. G. ; Mavromoustakos, T. Insights Into The Molecular Basis Of Action Of The At1 Antagonist Losartan Using A Combined Nmr Spectroscopy And Computational Approach. Biochimica et Biophysica Acta - Biomembranes 2014, 1838, 1031 - 1046. Website
Patrikios, I. S. ; Mavromoustakos, T. M. Monounsaturated Fatty Acid Ether Oligomers Formed During Heating Of Virgin Olive Oil Show Agglutination Activity Against Human Red Blood Cells. Journal of Agricultural and Food Chemistry 2014, 62, 867 - 874. Website
Stavrinoudakis, N. ; Kellici, T. ; Magrioti, V. ; Kokotos, G. ; Mavromoustakos, T. Physiological Function Of The Enzyme Monoacylglycerol Lipase And The Pharmaceutical Action Of Its Inhibitors. Epitheorese Klinikes Farmakologias kai Farmakokinetikes 2014, 32, 79 - 90. Website
Spyridaki, K. ; Matsoukas, M. - T. ; Cordomi, A. ; Gkountelias, K. ; Papadokostaki, M. ; Mavromoustakos, T. ; Logothetis, D. E. ; Margioris, A. N. ; Pardo, L. ; Liapakis, G. Structural-Functional Analysis Of The Third Transmembrane Domain Of The Corticotropin-Releasing Factor Type 1 Receptor Role In Activation And Allosteric Antagonism. Journal of Biological Chemistry 2014, 289, 18966 - 18977. Website
Tzoupis, H. ; Leonis, G. ; Avramopoulos, A. ; Mavromoustakos, T. ; Papadopoulos, M. G. Systematic Molecular Dynamics, Mm-Pbsa, And Ab Initio Approaches To The Saquinavir Resistance Mechanism In Hiv-1 Pr Due To 11 Double And Multiple Mutations. Journal of Physical Chemistry B 2014, 118, 9538 - 9552. Website
2013
Tzoupis, H. ; Leonis, G. ; Mavromoustakos, T. ; Papadopoulos, M. G. A Comparative Molecular Dynamics, Mm-Pbsa And Thermodynamic Integration Study Of Saquinavir Complexes With Wild-Type Hiv-1 Pr And L10I, G48V, L63P, A71V, G73S, V82A And I84V Single Mutants. Journal of Chemical Theory and Computation 2013, 9, 1754 - 1764. Website
Agelis, G. ; Kelaidonis, K. ; Resvani, A. ; Kalavrizioti, D. ; Androutsou, M. - E. ; Plotas, P. ; Vlahakos, D. ; Koukoulitsa, C. ; Tselios, T. ; Mavromoustakos, T. ; et al. Facile And Efficient Syntheses Of A Series Of N-Benzyl And N-Biphenylmethyl Substituted Imidazole Derivatives Based On (E)-Urocanic Acid, As Angiotensin Ii At1 Receptor Blockers. Molecules 2013, 18, 7510 - 7532. Website
Agelis, G. ; Resvani, A. ; Ntountaniotis, D. ; Chatzigeorgiou, P. ; Koukoulitsa, C. ; Androutsou, M. E. ; Plotas, P. ; Matsoukas, J. ; Mavromoustakos, T. ; Čendak, T. ; et al. Interactions Of The Potent Synthetic At1 Antagonist Analog Bv6 With Membrane Bilayers And Mesoporous Silicate Matrices. Biochimica et Biophysica Acta - Biomembranes 2013, 1828, 1846 - 1855. Website
Kritsi, E. ; Potamitis, C. ; Durdagi, S. ; Zoumpoulakis, P. ; Golic Grdadolnik, S. ; Mavromoustakos, T. Molecular Insights Into The At1 Antagonism Based On Biophysical And In Silico Studies Of Telmisartan. Medicinal Chemistry Research 2013, 22, 4842 - 4857. Website
Agelis, G. ; Resvani, A. ; Koukoulitsa, C. ; Tůmová, T. ; Slaninová, J. ; Kalavrizioti, D. ; Spyridaki, K. ; Afantitis, A. ; Melagraki, G. ; Siafaka, A. ; et al. Rational Design, Efficient Syntheses And Biological Evaluation Of N,n'-Symmetrically Bis-Substituted Butylimidazole Analogs As A New Class Of Potent Angiotensin Ii Receptor Blockers. European Journal of Medicinal Chemistry 2013, 62, 352 - 370. Website
Moutevelis-Minakakis, P. ; Papavassilopoulou, E. ; Mavromoustakos, T. Synthesis Of New Optically Active 2-Pyrrolidinones. Molecules 2013, 18, 50 - 73. Website
Mavromoustakos, T. Thoughts On The Historical Discovery Of Dna. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 2013, 27, 39 - 44. Website
Mavromoustakos, T. ; Agelis, G. ; Durdagi, S. At1 Antagonists: A Patent Review (2008 - 2012). Expert Opinion on Therapeutic Patents 2013, 23, 1483 - 1494. Website
Koulouridi, E. ; Langer, T. ; Bryant, S. D. ; Mavromoustakos, T. Rational Approach For The Discovery Of Lead-Compounds Using Pharmacophore Models. The Use Of Drug Databank Zinc In Virtual Screening. Pharmakeftiki 2013, 25, 123 - 134. Website
2012
Durdagi, S. ; Papadopoulos, M. G. ; Mavromoustakos, T. An Effort To Discover The Preferred Conformation Of The Potent Amg3 Cannabinoid Analog When Reaching The Active Sites Of The Cannabinoid Receptors. European Journal of Medicinal Chemistry 2012, 47, 44 - 51. Website
Mouchlis, V. D. ; Michopoulou, V. ; Constantinou-Kokotou, V. ; Mavromoustakos, T. ; Dennis, E. A. ; Kokotos, G. Binding Conformation Of 2-Oxoamide Inhibitors To Group Iva Cytosolic Phospholipase A 2 Determined By Molecular Docking Combined With Molecular Dynamics. Journal of Chemical Information and Modeling 2012, 52, 243 - 254. Website
Fotakis, C. ; Megariotis, G. ; Christodouleas, D. ; Kritsi, E. ; Zoumpoulakis, P. ; Ntountaniotis, D. ; Zervou, M. ; Potamitis, C. ; Hodzic, A. ; Pabst, G. ; et al. Comparative Study Of The At1 Receptor Prodrug Antagonist Candesartan Cilexetil With Other Sartans On The Interactions With Membrane Bilayers. Biochimica et Biophysica Acta - Biomembranes 2012, 1818, 3107 - 3120. Website
Varvarigou, N. ; Megariotis, G. ; Leonis, G. ; Vrontaki, E. ; Maniati, A. - M. ; Vlachou, M. ; Eikosipentaki, A. ; Kompogennitaki, R. ; Papadopoulos, M. G. ; Grdadolnik, S. G. ; et al. Conformational Analysis Of Two Novel Cytotoxic C2-Substituted Pyrrolo[2,3-F]Quinolines In Aqueous Media, Organic Solvents, Membrane Bilayers And At The Putative Active Site. Bioorganic and Medicinal Chemistry 2012, 20, 6276 - 6284. Website
Batsala, G. K. ; Dokorou, V. ; Kourkoumelis, N. ; Manos, M. J. ; Tasiopoulos, A. J. ; Mavromoustakos, T. ; Simčič, M. ; Golič-Grdadolnik, S. ; Hadjikakou, S. K. Copper(I)/(Ii) Or Silver(I) Ions Towards 2-Mercaptopyrimidine: An Exploration Of A Chemical Variability With Possible Biological Implication. Inorganica Chimica Acta 2012, 382, 146 - 157. Website
Agelis, G. ; Resvani, A. ; Durdagi, S. ; Spyridaki, K. ; Tůmová, T. ; Slaninová, J. ; Giannopoulos, P. ; Vlahakos, D. ; Liapakis, G. ; Mavromoustakos, T. ; et al. The Discovery Of New Potent Non-Peptide Angiotensin Ii At1 Receptor Blockers: A Concise Synthesis, Molecular Docking Studies And Biological Evaluation Of N-Substituted 5-Butylimidazole Derivatives. European Journal of Medicinal Chemistry 2012, 55, 358 - 374. Website
Tzoupis, H. ; Leonis, G. ; Megariotis, G. ; Supuran, C. T. ; Mavromoustakos, T. ; Papadopoulos, M. G. Dual Inhibitors For Aspartic Proteases Hiv-1 Pr And Renin: Advancements In Aids-Hypertension-Diabetes Linkage Via Molecular Dynamics, Inhibition Assays, And Binding Free Energy Calculations. Journal of Medicinal Chemistry 2012, 55, 5784 - 5796. Website
Ntountaniotis, D. ; Mali, G. ; Grdadolnik, S. G. ; Halabalaki, M. ; Skaltsounis, A. - L. ; Potamitis, C. ; Siapi, E. ; Chatzigeorgiou, P. ; Rappolt, M. ; Mavromoustakos, T. Erratum: Thermal, Dynamic And Structural Properties Of Drug At 1 Antagonist Olmesartan In Lipid Bilayers (Biochimica Et Biophysica Acta (2011) 1808 (2995-3006)). Biochimica et Biophysica Acta - Biomembranes 2012, 1818, 1436. Website
Hodzic, A. ; Zoumpoulakis, P. ; Pabst, G. ; Mavromoustakos, T. ; Rappolt, M. Losartan's Affinity To Fluid Bilayers Modulates Lipid-Cholesterol Interactions. Physical Chemistry Chemical Physics 2012, 14, 4780 - 4788. Website
Mouchlis, V. D. ; Melagraki, G. ; Mavromoustakos, T. ; Kollias, G. ; Afantitis, A. Molecular Modeling On Pyrimidine-Urea Inhibitors Of Tnf-Α Production: An Integrated Approach Using A Combination Of Molecular Docking, Classification Techniques, And 3D-Qsar Comsia. Journal of Chemical Information and Modeling 2012, 52, 711 - 723. Website
Tzoupis, H. ; Avramopoulos, A. ; Reis, H. ; Leonis, G. ; Durdagi, S. ; Mavromoustakos, T. ; Megariotis, G. ; Papadopoulos, M. G. Theoretical Studies Of Interactions In Nanomaterials And Biological Systems; 2012; pp. 148 - 185. Website
Vrontaki, E. ; Leonis, G. ; Papadopoulos, M. G. ; Simcic, M. ; Grdadolnik, S. G. ; Afantitis, A. ; Melagraki, G. ; Hadjikakou, S. K. ; Mavromoustakos, T. Comparative Binding Effects Of Aspirin And Anti-Inflammatory Cu Complex In The Active Site Of Lox-1. Journal of Chemical Information and Modeling 2012, 52, 3293 - 3301. Website
Politi, A. ; Ntountaniotis, D. ; Mavromoustakos, T. Design Of The Potent Renin Inhibitor Aliskiren With The Use Of Molecular Modeling, A Representative Instance Of Rational Drug Design. Epitheorese Klinikes Farmakologias kai Farmakokinetikes 2012, 30, 173 - 188. Website
Ntountaniotis, D. ; Tsantili-Kakoulidou, A. ; Mavromoustakos, T. Interactions Of Bioactive Molecules With Membranes And The Contribution Of Lipidomics In The Pharmaceutical Research. Pharmakeftiki 2012, 24, 89 - 105. Website
2011
Mouchlis, V. D. ; Barbayianni, E. ; Mavromoustakos, T. M. ; Kokotos, G. The Application Of Rational Design On Phospholipase A2 Inhibitors. Current Medicinal Chemistry 2011, 18, 2566 - 2582. Website
Fotakis, C. ; Christodouleas, D. ; Zoumpoulakis, P. ; Kritsi, E. ; Benetis, N. - P. ; Mavromoustakos, T. ; Reis, H. ; Gili, A. ; Papadopoulos, M. G. ; Zervou, M. Comparative Biophysical Studies Of Sartan Class Drug Molecules Losartan And Candesartan (Cv-11974) With Membrane Bilayers. Journal of Physical Chemistry B 2011, 115, 6180 - 6192. Website
Neophytou, N. ; Leonis, G. ; Stavrinoudakis, N. ; Simčič, M. M. ; Grdadolnik, S. G. ; Papavassilopoulou, E. ; Michas, G. ; Moutevelis-Minakakis, P. ; Papadopoulos, M. G. ; Zing, M. ; et al. Docking And Molecular Dynamics Calculations Of Pyrrolidinone Analog Mmk16 Bound To Cox And Lox Enzymes. Molecular Informatics 2011, 30, 473 - 486. Website
Mouchlis, V. D. ; Magrioti, V. ; Barbayianni, E. ; Cermak, N. ; Oslund, R. C. ; Mavromoustakos, T. M. ; Gelb, M. H. ; Kokotos, G. Inhibition Of Secreted Phospholipases A2 By 2-Oxoamides Based On Α-Amino Acids: Synthesis, In Vitro Evaluation And Molecular Docking Calculations. Bioorganic and Medicinal Chemistry 2011, 19, 735 - 743. Website
Potamitis, C. ; Chatzigeorgiou, P. ; Siapi, E. ; Viras, K. ; Mavromoustakos, T. ; Hodzic, A. ; Pabst, G. ; Cacho-Nerin, F. ; Laggner, P. ; Rappolt, M. Interactions Of The At1 Antagonist Valsartan With Dipalmitoyl-Phosphatidylcholine Bilayers. Biochimica et Biophysica Acta - Biomembranes 2011, 1808, 1753 - 1763. Website
Mavromoustakos, T. ; Chatzigeorgiou, P. ; Koukoulitsa, C. ; Durdagi, S. Partial Interdigitation Of Lipid Bilayers. International Journal of Quantum Chemistry 2011, 111, 1172 - 1183. Website
Mavromoustakos, T. ; Durdagi, S. ; Koukoulitsa, C. ; Simcic, M. ; Papadopoulos, M. G. ; Hodoscek, M. ; Grdadolnik, S. G. Strategies In The Rational Drug Design. Current Medicinal Chemistry 2011, 18, 2517 - 2530. Website
Moutevelis-Minakakis, P. ; Papavassilopoulou, E. ; Michas, G. ; Georgikopoulou, K. ; Ragoussi, M. - E. ; Neophytou, N. ; Zoumpoulakis, P. ; Mavromoustakos, T. ; Hadjipavlou-Litina, D. Synthesis, In Silico Docking Experiments Of New 2-Pyrrolidinone Derivatives And Study Of Their Anti-Inflammatory Activity. Bioorganic and Medicinal Chemistry 2011, 19, 2888 - 2902. Website
Tzoupis, H. ; Leonis, G. ; Durdagi, S. ; Mouchlis, V. ; Mavromoustakos, T. ; Papadopoulos, M. G. Binding Of Novel Fullerene Inhibitors To Hiv-1 Protease: Insight Through Molecular Dynamics And Molecular Mechanics Poisson-Boltzmann Surface Area Calculations. Journal of Computer-Aided Molecular Design 2011, 25, 959 - 976. Website
Koukoulitsa, C. ; Durdagi, S. ; Siapi, E. ; Villalonga-Barber, C. ; Alexi, X. ; Steele, B. R. ; Micha-Screttas, M. ; Alexis, M. N. ; Tsantili-Kakoulidou, A. ; Mavromoustakos, T. Comparison Of Thermal Effects Of Stilbenoid Analogs In Lipid Bilayers Using Differential Scanning Calorimetry And Molecular Dynamics: Correlation Of Thermal Effects And Topographical Position With Antioxidant Activity. European Biophysics Journal 2011, 40, 865 - 875. Website
Potamitis, C. ; Matsoukas, M. - T. ; Tselios, T. ; Mavromoustakos, T. ; Golič Grdadolnik, S. Conformational Analysis Of The Μβρ 83-99 (Phe 91) And Μβρ 83-99 (Tyr 91) Peptide Analogues And Study Of Their Interactions With The Hla-Dr2 And Human Tcr Receptors By Using Molecular Dynamics. Journal of Computer-Aided Molecular Design 2011, 25, 837 - 853. Website
Politi, A. ; Leonis, G. ; Tzoupis, H. ; Ntountaniotis, D. ; Papadopoulos, M. G. ; Grdadolnik, S. G. ; Mavromoustakos, T. Conformational Properties And Energetic Analysis Of Aliskiren In Solution And Receptor Site. Molecular Informatics 2011, 30, 973 - 985. Website
Mavromoustakos, T. Current Medicinal Chemistry: Editorial. Current Medicinal Chemistry 2011, 18, 2516. Website
Mavromoustakos, T. Editorial. Current Medicinal Chemistry 2011, 18, 2516. Website
Mavromoustakos, T. Methodologies And Applied Strategies In The Rational Drug Design. Current medicinal chemistry 2011, 18, 2516. Website
Poyraz, M. ; Banti, C. N. ; Kourkoumelis, N. ; Dokorou, V. ; Manos, M. J. ; Simčič, M. ; Golič-Grdadolnik, S. ; Mavromoustakos, T. ; Giannoulis, A. D. ; Verginadis, I. I. ; et al. Synthesis, Structural Characterization And Biological Studies Of Novel Mixed Ligand Ag(I) Complexes With Triphenylphosphine And Aspirin Or Salicylic Acid. Inorganica Chimica Acta 2011, 375, 114 - 121. Website
Ntountaniotis, D. ; Mali, G. ; Grdadolnik, S. G. ; Maria, H. ; Skaltsounis, A. - L. ; Potamitis, C. ; Siapi, E. ; Chatzigeorgiou, P. ; Rappolt, M. ; Mavromoustakos, T. Thermal, Dynamic And Structural Properties Of Drug At 1 Antagonist Olmesartan In Lipid Bilayers. Biochimica et Biophysica Acta - Biomembranes 2011, 1808, 2995 - 3006. Website
2010
Durdagi, S. ; Papadopoulos, M. G. ; Zoumpoulakis, P. G. ; Koukoulitsa, C. ; Mavromoustakos, T. A Computational Study On Cannabinoid Receptors And Potent Bioactive Cannabinoid Ligands: Homology Modeling, Docking, De Novo Drug Design And Molecular Dynamics Analysis. Molecular Diversity 2010, 14, 257 - 276. Website
Mouchlis, V. D. ; Mavromoustakos, T. M. ; Kokotos, G. Design Of New Secreted Phospholipase A2 Inhibitors Based On Docking Calculations By Modifying The Pharmacophore Segments Of The Fpl67047Xx Inhibitor. Journal of Computer-Aided Molecular Design 2010, 24, 107 - 115. Website
Agelis, G. ; Roumelioti, P. ; Resvani, A. ; Durdagi, S. ; Androutsou, M. - E. ; Kelaidonis, K. ; Vlahakos, D. ; Mavromoustakos, T. ; Matsoukas, J. An Efficient Synthesis Of A Rationally Designed 1,5 Disubstituted Imidazole At1 Angiotensin Ii Receptor Antagonist: Reorientation Of Imidazole Pharmacophore Groups In Losartan Reserves High Receptor Affinity And Confirms Docking Studies. Journal of Computer-Aided Molecular Design 2010, 24, 749 - 758. Website
Politi, A. P. ; Zervou, M. V. ; Triantafyllidi, H. ; Zoumpoulakis, P. G. ; Mavromoustakos, T. M. ; Zoga, A. A. ; Moutevelis-Minakakis, P. ; Kokotos, G. ; Iliodromitis, E. K. ; Kremastinos, D. T. Hypertension Study In Anaesthetized Rabbits: Protocol Proposal For At 1 Antagonists Screening. JRAAS - Journal of the Renin-Angiotensin-Aldosterone System 2010, 11, 103 - 110. Website
Fotakis, C. ; Gega, S. ; Siapi, E. ; Potamitis, C. ; Viras, K. ; Moutevelis-Minakakis, P. ; Kokotos, C. G. ; Durdagi, S. ; Grdadolnik, S. G. ; Sartori, B. ; et al. Interactions At The Bilayer Interface And Receptor Site Induced By The Novel Synthetic Pyrrolidinone Analog Mmk3. Biochimica et Biophysica Acta - Biomembranes 2010, 1798, 422 - 432. Website
Politi, A. ; Durdagi, S. ; Moutevelis-Minakakis, P. ; Kokotos, G. ; Mavromoustakos, T. Development Of Accurate Binding Affinity Predictions Of Novel Renin Inhibitors Through Molecular Docking Studies. Journal of Molecular Graphics and Modelling 2010, 29, 425 - 435. Website
Mouchlis, V. D. ; Mavromoustakos, T. M. ; Kokotos, G. Molecular Docking And 3D-Qsar Comfa Studies On Indole Inhibitors Of Giia Secreted Phospholipase A2. Journal of Chemical Information and Modeling 2010, 50, 1589 - 1601. Website
2009
Potamitis, C. ; Zervou, M. ; Katsiaras, V. ; Zoumpoulakis, P. ; Durdagi, S. ; Papadopoulos, M. G. ; Hayes, J. M. ; Grdadolnik, S. G. ; Kyrikou, I. ; Argyropoulos, D. ; et al. Antihypertensive Drug Valsartan In Solution And At The At1 Receptor: Conformational Analysis, Dynamic Nmr Spectroscopy, In Silico Docking, And Molecular Dynamics Simulations. Journal of Chemical Information and Modeling 2009, 49, 726 - 739. Website
Durdagi, S. ; Supuran, C. T. ; Strom, T. A. ; Doostdar, N. ; Kumar, M. K. ; Barron, A. R. ; Mavromoustakos, T. ; Papadopoulos, M. G. In Silico Drug Screening Approach For The Design Of Magic Bullets: A Successful Example With Anti-Hiv Fullerene Derivatized Amino Acids. Journal of Chemical Information and Modeling 2009, 49, 1139 - 1143. Website
Mannina, L. ; D'Imperio, M. ; Capitani, D. ; Rezzi, S. ; Guillou, C. ; Mavromoustakos, T. ; Vilchez, M. D. M. ; Fernández, A. H. ; Thomas, F. ; Aparicio, R. 1H Nmr-Based Protocol For The Detection Of Adulterations Of Refined Olive Oil With Refined Hazelnut Oil. Journal of Agricultural and Food Chemistry 2009, 57, 11550 - 11556. Website
Politi, A. ; Durdagi, S. ; Moutevelis-Minakakis, P. ; Kokotos, G. ; Papadopoulos, M. G. ; Mavromoustakos, T. Application Of 3D Qsar Comfa/comsia And In Silico Docking Studies On Novel Renin Inhibitors Against Cardiovascular Diseases. European Journal of Medicinal Chemistry 2009, 44, 3703 - 3711. Website
Fotakis, C. ; Christodouleas, D. ; Chatzigeorgiou, P. ; Zervou, M. ; Benetis, N. - P. ; Viras, K. ; Mavromoustakos, T. Development Of A Cp 31P Nmr Broadline Simulation Methodology For Studying The Interactions Of Antihypertensive At1 Antagonist Losartan With Phospholipid Bilayers. Biophysical Journal 2009, 96, 2227 - 2236. Website
Koukoulitsa, C. ; Tsantili-Kakoulidou, A. ; Mavromoustakos, T. ; Chinou, I. Pls Analysis For Antibacterial Activity Of Natural Coumarins Using Volsurf Descriptors. QSAR and Combinatorial Science 2009, 28, 785 - 789. Website
Kotzabasakis, V. ; Kostakis, K. ; Pitsikalis, M. ; Hadjichristidis, N. ; Lohse, D. J. ; Mavromoustakos, T. ; Potamitis, C. Polymerization Of Higher Α-Olefins Using A C S-Symmetry Hafnium Metallocene Catalyst. Kinetics Of The Polymerization And Microstructural Analysis. Journal of Polymer Science, Part A: Polymer Chemistry 2009, 47, 4314 - 4325. Website
2008
Durdagi, S. ; Mavromoustakos, T. ; Papadopoulos, M. G. 3D Qsar Comfa/comsia, Molecular Docking And Molecular Dynamics Studies Of Fullerene-Based Hiv-1 Pr Inhibitors. Bioorganic and Medicinal Chemistry Letters 2008, 18, 6283 - 6289. Website
Kapou, A. ; Benetis, N. - P. ; Durdagi, S. ; Nikolaropoulos, S. ; Mavromoustakos, T. 3D Qsar/comfa And Comsia Studies On Antileukemic Steroidal Esters Coupled With Conformationally Flexible Nitrogen Mustards. Journal of Chemical Information and Modeling 2008, 48, 2254 - 2264. Website
Mantzourani, E. D. ; Blokar, K. ; Tselios, T. V. ; Matsoukas, J. M. ; Platts, J. A. ; Mavromoustakos, T. M. ; Grdadolnik, S. G. A Combined Nmr And Molecular Dynamics Simulation Study To Determine The Conformational Properties Of Agonists And Antagonists Against Experimental Autoimmune Encephalomyelitis. Bioorganic and Medicinal Chemistry 2008, 16, 2171 - 2182. Website
Koukoulitsa, C. ; Zervou, M. ; Demetzos, C. ; Mavromoustakos, T. Comparative Docking Studies Of Labdane-Type Diterpenes With Forskolin At The Active Site Of Adenylyl Cyclase. Bioorganic and Medicinal Chemistry 2008, 16, 8237 - 8243. Website
Durdagi, S. ; Reis, H. ; Papadopoulos, M. G. ; Mavromoustakos, T. Comparative Molecular Dynamics Simulations Of The Potent Synthetic Classical Cannabinoid Ligand Amg3 In Solution And At Binding Site Of The Cb1 And Cb2 Receptors. Bioorganic and Medicinal Chemistry 2008, 16, 7377 - 7387. Website
Durdagi, S. ; Mavromoustakos, T. ; Chronakis, N. ; Papadopoulos, M. G. Computational Design Of Novel Fullerene Analogues As Potential Hiv-1 Pr Inhibitors: Analysis Of The Binding Interactions Between Fullerene Inhibitors And Hiv-1 Pr Residues Using 3D Qsar, Molecular Docking And Molecular Dynamics Simulations. Bioorganic and Medicinal Chemistry 2008, 16, 9957 - 9974. Website
Panagiotidis, P. ; Kefalas, E. T. ; Raptopoulou, C. P. ; Terzis, A. ; Mavromoustakos, T. ; Salifoglou, A. Delving Into The Complex Picture Of Ti(Iv)-Citrate Speciation In Aqueous Media: Synthetic, Structural, And Electrochemical Considerations In Mononuclear Ti(Iv) Complexes Containing Variably Deprotonated Citrate Ligands. Inorganica Chimica Acta 2008, 361, 2210 - 2224. Website
Kyrikou, I. ; Benetis, N. P. ; Chatzigeorgiou, P. ; Zervou, M. ; Viras, K. ; Poulos, C. ; Mavromoustakos, T. Interactions Of The Dipeptide Paralysin Β-Ala-Tyr And The Aminoacid Glu With Phospholipid Bilayers. Biochimica et Biophysica Acta - Biomembranes 2008, 1778, 113 - 124. Website
2007
Kapou, A. ; Benetis, N. P. ; Avlonitis, N. ; Calogeropoulou, T. ; Koufaki, M. ; Scoulica, E. ; Nikolaropoulos, S. S. ; Mavromoustakos, T. 3D-Quantitative Structure-Activity Relationships Of Synthetic Antileishmanial Ring-Substituted Ether Phospholipids. Bioorganic and Medicinal Chemistry 2007, 15, 1252 - 1265. Website
Durdagi, S. ; Kapou, A. ; Kourouli, T. ; Andreou, T. ; Nikas, S. P. ; Nahmias, V. R. ; Papahatjis, D. P. ; Papadopoulos, M. G. ; Mavromoustakos, T. The Application Of 3D-Qsar Studies For Novel Cannabinoid Ligands Substituted At The C1′ Position Of The Alkyl Side Chain On The Structural Requirements For Binding To Cannabinoid Receptors Cb1 And Cb2. Journal of Medicinal Chemistry 2007, 50, 2875 - 2885. Website
Durdagi, S. ; Papadopoulos, M. G. ; Papahatjis, D. P. ; Mavromoustakos, T. Combined 3D Qsar And Molecular Docking Studies To Reveal Novel Cannabinoid Ligands With Optimum Binding Activity. Bioorganic and Medicinal Chemistry Letters 2007, 17, 6754 - 6763. Website
Mantzourani, E. D. ; Platts, J. A. ; Brancale, A. ; Mavromoustakos, T. M. ; Tselios, T. V. Molecular Dynamics At The Receptor Level Of Immunodominant Myelin Basic Protein Epitope 87-99 Implicated In Multiple Sclerosis And Its Antagonists Altered Peptide Ligands: Triggering Of Immune Response. Journal of Molecular Graphics and Modelling 2007, 26, 471 - 481. Website
Spyranti, Z. ; Dalkas, G. A. ; Spyroulias, G. A. ; Mantzourani, E. D. ; Mavromoustakos, T. ; Friligou, I. ; Matsoukas, J. M. ; Tselios, T. V. Putative Bioactive Conformations Of Amide Linked Cyclic Myelin Basic Protein Peptide Analogues Associated With Experimental Autoimmune Encephalomyelitis. Journal of Medicinal Chemistry 2007, 50, 6039 - 6047. Website
Mavromoustakos, T. M. The Use Of Differential Scanning Calorimetry To Study Drug-Membrane Interactions; 2007; Vol. 400, pp. 587 - 600. Website
2006
Mavromoustakos, T. M. ; Zervou, M. V. ; Zoumpoulakis, P. G. Design And Discovery Of Novel Antihypertensive Drugs Through Conformation And Bioactivity Studies; 2006; Vol. 3, pp. 87 - 111. Website
Keramida, M. K. ; Tselios, T. ; Mantzourani, E. ; Papazisis, K. ; Mavromoustakos, T. ; Klaussen, C. ; Agelis, G. ; Deraos, S. ; Friligou, I. ; Habibi, H. ; et al. Design, Synthesis, And Molecular Modeling Of A Novel Amide-Linked Cyclic Gnrh Analogue Cyclo(4-9)[Lys4,d-Trp6,glu9]Gnrh: Stimulation Of Gonadotropin Gene Expression. Journal of Medicinal Chemistry 2006, 49, 105 - 110. Website
Zoumpoulakis, P. ; Politi, A. ; Grdadolnik, S. G. ; Matsoukas, J. ; Mavromoustakos, T. Structure Elucidation And Conformational Study Of V8: A Novel Synthetic Non Peptide At1 Antagonist. Journal of Pharmaceutical and Biomedical Analysis 2006, 40, 1097 - 1104. Website
Saroglou, V. ; Hatziantoniou, S. ; Smyrniotakis, M. ; Kyrikou, I. ; Mavromoustakos, T. ; Zompra, A. ; Magafa, V. ; Cordopatis, P. ; Demetzos, C. Synthesis, Liposomal Formulation And Thermal Effects On Phospholipid Bilayers Of Leuprolide. Journal of Peptide Science 2006, 12, 43 - 50. Website
Mantzourani, E. D. ; Tselios, T. V. ; Grdadolnik, S. G. ; Platts, J. A. ; Brancale, A. ; Deraos, G. N. ; Matsoukas, J. M. ; Mavromoustakos, T. M. Comparison Of Proposed Putative Active Conformations Of Myelin Basic Protein Epitope 87-99 Linear Altered Peptide Ligands By Spectroscopic And Modelling Studies: The Role Of Positions 91 And 96 In T-Cell Receptor Activation. Journal of Medicinal Chemistry 2006, 49, 6683 - 6691. Website
Mantzourani, E. D. ; Tselios, T. V. ; Grdadolnik, S. G. ; Brancale, A. ; Platts, J. A. ; Matsoukas, J. M. ; Mavromoustakos, T. M. A Putative Bioactive Conformation For The Altered Peptide Ligand Of Myelin Basic Protein And Inhibitor Of Experimental Autoimmune Encephalomyelitis [Arg91, Ala96] Mbp87-99. Journal of Molecular Graphics and Modelling 2006, 25, 17 - 29. Website
Koukoulitsa, C. ; Kyrikou, I. ; Demetzos, C. ; Mavromoustakos, T. The Role Of The Anticancer Drug Vinorelbine In Lipid Bilayers Using Differential Scanning Calorimetry And Molecular Modeling. Chemistry and Physics of Lipids 2006, 144, 85 - 95. Website
Mavromoustakos, T. ; Moutevelis-Minakakis, P. ; Kokotos, C. G. ; Kontogianni, P. ; Politi, A. ; Zoumpoulakis, P. ; Findlay, J. ; Cox, A. ; Balmforth, A. ; Zoga, A. ; et al. Synthesis, Binding Studies And In Vivo Biological Evaluation Of Novel Non-Peptide Antihypertensive Analogues. Bioorganic and Medicinal Chemistry 2006, 14, 4353 - 4360. Website
2005
Petrakis, P. ; Touris, I. ; Liouni, M. ; Zervou, M. ; Kyrikou, I. ; Kokkinofta, R. ; Theocharis, C. R. ; Mavromoustakos, T. M. Authenticity Of The Traditional Cypriot Spirit "zivania" On The Basis Of 1H Nmr Spectroscopy Diagnostic Parameters And Statistical Analysis. Journal of Agricultural and Food Chemistry 2005, 53, 5293 - 5303. Website
Kyrikou, I. ; Georgopoulos, A. ; Hatziantoniou, S. ; Mavromoustakos, T. ; Demetzos, C. A Comparative Study Of The Effects Of Cholesterol And Sclareol, A Bioactive Labdane Type Diterpene, On Phospholipid Bilayers. Chemistry and Physics of Lipids 2005, 133, 125 - 134. Website
Matsoukas, J. ; Apostolopoulos, V. ; Kalbacher, H. ; Papini, A. - M. ; Tselios, T. ; Chatzantoni, K. ; Biagioli, T. ; Lolli, F. ; Deraos, S. ; Papathanassopoulos, P. ; et al. Design And Synthesis Of A Novel Potent Myelin Basic Protein Epitope 87-99 Cyclic Analogue: Enhanced Stability And Biological Properties Of Mimics Render Them A Potentially New Class Of Immunomodulators. Journal of Medicinal Chemistry 2005, 48, 1470 - 1480. Website
Kapou, A. ; Nikolaropoulos, S. S. ; Siapi, E. ; Mavromoustakos, T. Effects Of Steroidal Carriers Of Alkylating Agents On The Phase Transition In Dppc Membrane Bilayers. Thermochimica Acta 2005, 429, 53 - 56. Website
Kefalas, E. T. ; Panagiotidis, P. ; Raptopoulou, C. P. ; Terzis, A. ; Mavromoustakos, T. ; Salifoglou, A. Mononuclear Titanium(Iv)-Citrate Complexes From Aqueous Solutions: Ph-Specific Synthesis And Structural And Spectroscopic Studies In Relevance To Aqueous Titanium(Iv)-Citrate Speciation. Inorganic Chemistry 2005, 44, 2596 - 2605. Website
Kefalas, E. T. ; Dakanali, M. ; Panagiotidis, P. ; Raptopoulou, C. P. ; Terzis, A. ; Mavromoustakos, T. ; Kyrikou, I. ; Karligiano, N. ; Bino, A. ; Salifoglou, A. Ph-Specific Aqueous Synthetic Chemistry In The Binary Cadmium(Ii)-Citrate System. Gaining Insight Into Cadmium(Ii)-Citrate Speciation With Relevance To Cadmium Toxicity. Inorganic Chemistry 2005, 44, 4818 - 4828. Website
Siapi, E. ; Mavromoustakos, T. ; Trandafir, V. ; Albu, B. ; Budrugeac, P. The Use Of Differential Scanning Calorimetry To Study The Effects Of Gentamycin On Fibrous Collageneous Membranes. Thermochimica Acta 2005, 425, 165 - 171. Website
Kapou, A. ; Fousteris, M. A. ; Nikolaropoulos, S. S. ; Zervou, M. ; Grdadolnik, S. G. ; Zoumpoulakis, P. ; Kyrikou, I. ; Mavromoustakos, T. 2D Nmr And Conformational Analysis Of A Prototype Anti-Tumour Steroidal Ester. Journal of Pharmaceutical and Biomedical Analysis 2005, 38, 428 - 434. Website
Preto, M. A. C. ; Melo, A. ; Maia, H. L. S. ; Mavromoustakos, T. ; Ramos, M. J. Molecular Dynamics Simulations Of Angiotensin Ii In Aqueous And Dimethyl Sulfoxide Environments. Journal of Physical Chemistry B 2005, 109, 17743 - 17751. Website
Souli, C. ; Avlonitis, N. ; Calogeropoulou, T. ; Tsotinis, A. ; Maksay, G. ; Bíró, T. ; Politi, A. ; Mavromoustakos, T. ; Makriyannis, A. ; Reis, H. ; et al. Novel 17Β-Substituted Conformationally Constrained Neurosteroids That Modulate GabaA Receptors. Journal of Medicinal Chemistry 2005, 48, 5203 - 5214. Website
Zoumpoulakis, P. ; Mavromoustakos, T. Seeking The Active Site Of The At1 Receptor For Computational Docking Studies. Drug Design Reviews Online 2005, 2, 537 - 545. Website
Benetis, N. - P. ; Kyrikou, I. ; Zervou, M. ; Mavromoustakos, T. Static Cp 31P Nmr Multilamellar Bilayer Broadlines In The Absence And Presence Of The Bioactive Dipeptide Β-Ala-Tyr Or Glu. Chemical Physics 2005, 314, 57 - 72. Website
Mantzourani, E. D. ; Mavromoustakos, T. M. ; Platts, J. A. ; Matsoukas, J. M. ; Tselios, T. V. Structural Requirements For Binding Of Myelin Basic Protein (Mbp) Peptides To Mhc Ii: Effects On Immune Regulation. Current Medicinal Chemistry 2005, 12, 1521 - 1535. Website
2004
Mavromoustakos, T. ; Zervou, M. ; Zoumpoulakis, P. ; Kyrikou, I. ; Benetis, N. P. ; Polevaya, L. ; Roumelioti, P. ; Giatas, N. ; Zoga, A. ; Moutevelis Minakakis, P. ; et al. Conformation And Bioactivity. Design And Discovery Of Novel Antihypertensive Drugs. Current Topics in Medicinal Chemistry 2004, 4, 385 - 401. Website
Alexopoulos, K. ; Fatseas, P. ; Melissari, E. ; Vlahakos, D. ; Roumelioti, P. ; Mavromoustakos, T. ; Mihailescu, S. ; Paredes-Carbajal, M. C. ; Mascher, D. ; Matsoukas, J. Design And Synthesis Of Novel Biologically Active Thrombin Receptor Non-Peptide Mimetics Based On The Pharmacophoric Cluster Phe/arg/nh2 Of The Ser42-Phe-Leu-Leu-Arg46 Motif Sequence: Platelet Aggregation And Relaxant Acti. Journal of Medicinal Chemistry 2004, 47, 3338 - 3352. Website
Batsoulis, A. N. ; Nacos, M. K. ; Pappas, C. S. ; Tarantilis, P. A. ; Mavromoustakos, T. ; Polissiou, M. G. Determination Of Uronic Acids In Isolated Hemicelluloses From Kenaf Using Diffuse Reflectance Infrared Fourier Transform Spectroscopy (Drifts) And The Curve-Fitting Deconvolution Method. Applied Spectroscopy 2004, 58, 199 - 202. Website
Mavromoustakos, T. ; Zoumpoulakis, P. ; Kyrikou, I. ; Zoga, A. ; Siapi, E. ; Zervou, M. ; Daliani, I. ; Dimitriou, D. ; Pitsas, A. ; Kamoutsis, C. ; et al. Efforts To Understand The Molecular Basis Of Hypertension Through Drug: Membrane Interactions. Current Topics in Medicinal Chemistry 2004, 4, 445 - 459. Website
Marathias, K. P. ; Agroyannis, B. ; Mavromoustakos, T. ; Matsoukas, J. ; Vlahakos, D. V. Hematocrit-Lowering Effect Following Inactivation Of Renin-Angiotensin System With Angiotensin Converting Enzyme Inhibitors And Angiotensin Receptors Blockers. Current Topics in Medicinal Chemistry 2004, 4, 483 - 486. Website
Mavromoustakos, T. Modern Aspects In The Design And Discovery Of Novel Antihypertensive Drugs. Current Topics in Medicinal Chemistry 2004, 4. Website
Kyrikou, I. ; Daliani, I. ; Mavromoustakos, T. ; Maswadeh, H. ; Demetzos, C. ; Hatziantoniou, S. ; Giatrellis, S. ; Nounesis, G. The Modulation Of Thermal Properties Of Vinblastine By Cholesterol In Membrane Bilayers. Biochimica et Biophysica Acta - Biomembranes 2004, 1661, 1 - 8. Website
Kyrikou, I. ; Hadjikakou, S. K. ; Kovala-Demertzi, D. ; Viras, K. ; Mavromoustakos, T. Effects Of Non-Steroid Anti-Inflammatory Drugs In Membrane Bilayers. Chemistry and Physics of Lipids 2004, 132, 157 - 169. Website
Triantafyllidis, K. S. ; Nalbandian, L. ; Trikalitis, P. N. ; Ladavos, A. K. ; Mavromoustakos, T. ; Nicolaides, C. P. Structural, Compositional And Acidic Characteristics Of Nanosized Amorphous Or Partially Crystalline Zsm-5 Zeolite-Based Materials. Microporous and Mesoporous Materials 2004, 75, 89 - 100. Website
Kovala-Demertzi, D. ; Vidjeluc, C. ; Demertzis, M. A. ; Siapi, E. ; Mavromoustakos, T. The Thermal Effects Of Platinum(Ii) And Palladium(Ii) Complexes With 2-Acetyl Pyridine And Pyridine-2-Carbaldehyde N(4)-Ethyl-Thiosemicarbazones In Membrane Bilayers. Thermochimica Acta 2004, 424, 53 - 58. Website
2003
Avlonitis, N. ; Lekka, E. ; Detsi, A. ; Koufaki, M. ; Calogeropoulou, T. ; Scoulica, E. ; Siapi, E. ; Kyrikou, I. ; Mavromoustakos, T. ; Tsotinis, A. ; et al. Antileishmanial Ring-Substituted Ether Phospholipids. Journal of Medicinal Chemistry 2003, 46, 755 - 767. Website
Zoumpoulakis, P. ; Zoga, A. ; Roumelioti, P. ; Giatas, N. ; Grdadolnik, S. G. ; Iliodromitis, E. ; Vlahakos, D. ; Kremastinos, D. ; Matsoukas, J. M. ; Mavromoustakos, T. Conformational And Biological Studies For A Pair Of Novel Synthetic At1 Antagonists: Stereoelectronic Requirements For Antihypertensive Efficacy. Journal of Pharmaceutical and Biomedical Analysis 2003, 31, 833 - 844. Website
Moutevelis-Minakakis, P. ; Gianni, M. ; Stougiannou, H. ; Zoumpoulakis, P. ; Zoga, A. ; Vlahakos, A. D. ; Iliodromitis, E. ; Mavromoustakos, T. Design And Synthesis Of Novel Antihypertensive Drugs. Bioorganic and Medicinal Chemistry Letters 2003, 13, 1737 - 1740. Website
Kyrikou, I. ; Grdadolnik, S. G. ; Tatari, M. ; Poulos, C. ; Mavromoustakos, T. Structural Elucidation And Conformational Properties Of The Toxin Paralysin Β-Ala-Tyr. Journal of Pharmaceutical and Biomedical Analysis 2003, 31, 713 - 721. Website
Dakanali, M. ; Kefalas, E. T. ; Raptopoulou, C. P. ; Terzis, A. ; Mavromoustakos, T. ; Salifoglou, A. Synthesis And Spectroscopic And Structural Studies Of A New Cadmium(Ii)-Citrate Aqueous Complex. Potential Relevance To Cadmium(Ii)-Citrate Speciation And Links To Cadmium Toxicity. Inorganic Chemistry 2003, 42, 2531 - 2537. Website
Kokkinofta, R. ; Petrakis, P. V. ; Mavromoustakos, T. ; Theocharis, C. R. Authenticity Of The Traditional Cypriot Spirit "zivania" On The Basis Of Metal Content Using A Combination Of Coupled Plasma Spectroscopy And Statistical Analysis. Journal of Agricultural and Food Chemistry 2003, 51, 6233 - 6239. Website
Zoumpoulakis, P. ; Daliani, I. ; Zervou, M. ; Kyrikou, I. ; Siapi, E. ; Lamprinidis, G. ; Mikros, E. ; Mavromoustakos, T. Losartan's Molecular Basis Of Interaction With Membranes And At 1 Receptor. Chemistry and Physics of Lipids 2003, 125, 13 - 25. Website
Dakanali, M. ; Kefalas, E. T. ; Raptopoulou, C. P. ; Terzis, A. ; Voyiatzis, G. ; Kyrikou, I. ; Mavromoustakos, T. ; Salifoglou, A. A New Dinuclear Ti(Iv)-Peroxo-Citrate Complex From Aqueous Solutions. Synthetic, Structural, And Spectroscopic Studies In Relevance To Aqueous Titanium(Iv)-Peroxo-Citrate Speciation. Inorganic Chemistry 2003, 42, 4632 - 4639. Website
2002
Tselios, T. ; Apostolopoulos, V. ; Daliani, I. ; Deraos, S. ; Grdadolnik, S. ; Mavromoustakos, T. ; Melachrinou, M. ; Thymianou, S. ; Probert, L. ; Mouzaki, A. ; et al. Antagonistic Effects Of Human Cyclic Mbp87-99 Altered Peptide Ligands In Experimental Allergic Encephalomyelitis And Human T-Cell Proliferation. Journal of Medicinal Chemistry 2002, 45, 275 - 283. Website
Pappas, C. ; Tarantilis, P. A. ; Daliani, I. ; Mavromoustakos, T. ; Polissiou, M. Comparison Of Classical And Ultrasound-Assisted Isolation Procedures Of Cellulose From Kenaf (Hibiscus Cannabinus L.) And Eucalyptus (Eucalyptus Rodustrus Sm.). Ultrasonics Sonochemistry 2002, 9, 19 - 23. Website
Maswadeh, H. ; Demetzos, C. ; Dimas, K. ; Loukas, Y. L. ; Georgopoulos, A. ; Mavromoustakos, T. ; Papaioannou, G. T. In-Vitro Cytotoxic/cytostatic Activity Of Anionic Liposomes Containing Vinblastine Against Leukaemic Human Cell Lines. Journal of Pharmacy and Pharmacology 2002, 54, 189 - 196. Website
Apostolopoulos, V. ; Matsoukas, J. ; Plebanski, M. ; Mavromoustakos, T. Applications Of Peptide Mimetics In Cancer. Current Medicinal Chemistry 2002, 9, 411 - 420. Website
Pispas, S. ; Siakali-Kioulafa, E. ; Hadjichristidis, N. ; Mavromoustakos, T. Block Copolymers With Crystalline/amorphous, Crystalline/polyelectrolyte And Amorphous/polyelectrolyte Blocks. Macromolecular Chemistry and Physics 2002, 203, 1317 - 1327. Website
Roumelioti, P. ; Polevaya, L. ; Zoumpoulakis, P. ; Giatas, N. ; Mutule, I. ; Keivish, T. ; Zoga, A. ; Vlahakos, D. ; Iliodromitis, E. ; Kremastinos, D. ; et al. Design, Synthesis And Biological Evaluation Of Cyclic Angiotensin Ii Analogues With 3,5 Side-Chain Bridges: Role Of C-Terminal Aromatic Residue And Ring Cluster For Activity And Implications In The Drug Design Of At1 Non-Peptide Antagonists. Bioorganic and Medicinal Chemistry Letters 2002, 12, 2627 - 2633. Website
Maswadeh, H. ; Demetzos, C. ; Daliani, I. ; Kyrikou, I. ; Mavromoustakos, T. ; Tsortos, A. ; Nounesis, G. A Molecular Basis Explanation Of The Dynamic And Thermal Effects Of Vinblastine Sulfate Upon Dipalmitoylphosphatidylcholine Bilayer Membranes. Biochimica et Biophysica Acta - Biomembranes 2002, 1567, 49 - 55. Website
Zoumpoulakis, P. ; Grdadolnik, S. G. ; Matsoukas, J. ; Mavromoustakos, T. Structure Elucidation And Conformational Properties Of Eprosartan A Non Peptide Angiotensin Ii At1 Antagonist. Journal of Pharmaceutical and Biomedical Analysis 2002, 28, 125 - 135. Website
2001
Alexopoulos, K. ; Panagiotopoulos, D. ; Mavromoustakos, T. ; Fatseas, P. ; Paredes-Carbajal, M. C. ; Mascher, D. ; Mihailescu, S. ; Matsoukas, J. Design, Synthesis, And Modeling Of Novel Cyclic Thrombin Receptor-Derived Peptide Analogues Of The Ser42-Phe-Leu-Leu-Arg46 Motif Sequence With Fixed Conformations Of Pharmacophoric Groups: Importance Of A Phe/arg/nh2 Cluster For Receptor Activa. Journal of Medicinal Chemistry 2001, 44, 328 - 339. Website
Demetzos, C. ; Angelopoulou, D. ; Kolocouris, A. ; Daliani, I. ; Mavromoustakos, T. Structure Elucidation, Conformational Analysis And Thermal Effects On Membrane Bilayers Of An Antimicrobial Myricetin Ether Derivative. Journal of Heterocyclic Chemistry 2001, 38, 703 - 710. Website
Mavromoustakos, T. ; Apostolopoulos, V. ; Matsoukas, J. Antihypertensive Drugs That Act On Renin-Angiotensin System With Emphasis In At(1) Antagonists. Mini reviews in medicinal chemistry 2001, 1, 207 - 217. Website
Matsoukas, J. ; Apostolopoulos, V. ; Mavromoustakos, T. Designing Peptide Mimetics For The Treatment Of Multiple Sclerosis. Mini reviews in medicinal chemistry 2001, 1, 273 - 282. Website
Mavromoustakos, T. ; Papahatjis, D. ; Laggner, P. Differential Membrane Fluidization By Active And Inactive Cannabinoid Analogues. Biochimica et Biophysica Acta - Biomembranes 2001, 1512, 183 - 190. Website
Mavromoustakos, T. ; Calogeropoulou, T. ; Koufaki, M. ; Kolocouris, A. ; Daliani, I. ; Demetzos, C. ; Meng, Z. ; Makriyannis, A. ; Balzarini, J. ; De Clercq, E. Ether Phospholipid-Azt Conjugates Possessing Anti-Hiv And Antitumor Cell Activity. Synthesis, Conformational Analysis, And Study Of Their Thermal Effects On Membrane Bilayers. Journal of Medicinal Chemistry 2001, 44, 1702 - 1709. Website
Kolocouris, A. ; Mavromoustakos, T. ; Demetzos, C. ; Terzis, A. ; Grdadolnik, S. G. Structure Elucidation And Conformational Properties Of A Novel Bioactive Clerodane Diterpene Using A Combination Of High Field Nmr Spectroscopy, Computational Analysis And X-Ray Diffraction. Bioorganic and Medicinal Chemistry Letters 2001, 11, 837 - 840. Website
Polevaya, L. ; Mavromoustakos, T. ; Zoumboulakis, P. ; Grdadolnik, S. G. ; Roumelioti, P. ; Giatas, N. ; Mutule, I. ; Keivish, T. ; Vlahakos, D. V. ; Iliodromitis, E. K. ; et al. Synthesis And Study Of A Cyclic Angiotensin Ii Antagonist Analogue Reveals The Role Of Π*-Π* Interactions In The C-Terminal Aromatic Residue For Agonist Activity And Its Structure Resemblance With At1 Non-Peptide Antagonists. Bioorganic and Medicinal Chemistry 2001, 9, 1639 - 1647. Website
Matzapetakis, M. ; Kourgiantakis, M. ; Dakanali, M. ; Raptopoulou, C. P. ; Terzis, A. ; Lakatos, A. ; Kiss, T. ; Banyai, I. ; Iordanidis, L. ; Mavromoustakos, T. ; et al. Synthesis, Ph-Dependent Structural Characterization, And Solution Behavior Of Aqueous Aluminum And Gallium Citrate Complexes. Inorganic Chemistry 2001, 40, 1734 - 1744. Website
2000
Dimas, K. ; Demetzos, C. ; Angelopoulou, D. ; Kolokouris, A. ; Mavromoustakos, T. Biological Activity Of Myricetin And Its Derivatives Against Human Leukemic Cell Lines In Vitro. Pharmacological Research 2000, 42, 475 - 478. Website
Matsoukas, J. M. ; Polevaya, L. ; Ancans, J. ; Mavromoustakos, T. ; Kolocouris, A. ; Roumelioti, P. ; Vlahakos, D. V. ; Yamdagni, R. ; Wu, Q. ; Moore, G. J. The Design And Synthesis Of A Potent Angiotensin Ii Cyclic Analogue Confirms The Ring Cluster Receptor Conformation Of The Hormone Angiotensin Ii. Bioorganic and Medicinal Chemistry 2000, 8, 1 - 10. Website
Mavromoustakos, T. ; Zervou, M. ; Bonas, G. ; Kolocouris, A. ; Petrakis, P. Novel Analytical Method To Detect Adulteration Of Virgin Olive Oil By Other Oils. JAOCS, Journal of the American Oil Chemists' Society 2000, 77, 405 - 411. Website
Roumelioti, P. ; Tselios, T. ; Alexopoulos, K. ; Mavromoustakos, T. ; Kolocouris, A. ; Moore, G. J. ; Matsoukas, J. M. Structural Comparison Between Type I And Type Ii Antagonists: Possible Implications In The Drug Design Of At1 Antagonists. Bioorganic and Medicinal Chemistry Letters 2000, 10, 755 - 758. Website
Troganis, A. ; Gerothanassis, I. P. ; Athanassiou, Z. ; Mavromoustakos, T. ; Hawkes, G. E. ; Sakarellos, C. Thermodynamic Origin Of Cis/trans Isomers Of A Proline-Containing Β- Turn Model Dipeptide In Aqueous Solution: A Combined Variable Temperature 1H-Nmr, Two-Dimensional 1H, 1H Gradient Enhanced Nuclear Overhauser Effect Spectroscopy (Noesy), One-Dimensiona. Biopolymers 2000, 53, 72 - 83. Website
Tselios, T. ; Daliani, I. ; Deraos, S. ; Thymianou, S. ; Matsoukas, E. ; Troganis, A. ; Gerothanassis, I. ; Mouzaki, A. ; Mavromoustakos, T. ; Probert, L. ; et al. Treatment Of Experimental Allergic Encephalomyelitis (Eae) By A Rationally Designed Cyclic Analogue Of Myelin Basic Protein (Mbp) Epitope 72-85. Bioorganic and Medicinal Chemistry Letters 2000, 10, 2713 - 2717. Website
1999
Tselios, T. ; Probert, L. ; Daliani, I. ; Matsoukas, E. ; Troganis, A. ; Gerothanassis, I. P. ; Mavromoustakos, T. ; Moore, G. J. ; Matsoukas, J. M. Design And Synthesis Of A Potent Cyclic Analogue Of The Myelin Basic Protein Epitope Mbp72-85: Importance Of The Ala81 Carboxyl Group And Of A Cyclic Conformation For Induction Of Experimental Allergic Encephalomyelitis. Journal of Medicinal Chemistry 1999, 42, 1170 - 1177. Website
Alexopoulos, K. ; Fatseas, P. ; Melissari, E. ; Vlahakos, D. ; Smith, J. ; Mavromoustakos, T. ; Saifeddine, M. ; Moore, G. ; Hollenberg, M. ; Matsoukas, J. Design And Synthesis Of Thrombin Receptor-Derived Nonpeptide Mimetics Utilizing A Piperazine Scaffold. Bioorganic and Medicinal Chemistry 1999, 7, 1033 - 1041. Website
Mavromoustakos, T. ; Kolocouris, A. ; Zervou, M. ; Roumelioti, P. ; Matsoukas, J. ; Weisemann, R. An Effort To Understand The Molecular Basis Of Hypertension Through The Study Of Conformational Analysis Of Losartan And Sarmesin Using A Combination Of Nuclear Magnetic Resonance Spectroscopy And Theoretical Calculations. Journal of Medicinal Chemistry 1999, 42, 1714 - 1722. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Zervou, M. ; Kourouli, T. ; Papahatjis, D. Structure Elucidation And Conformational Properties Of Synthetic Cannabinoids (-)-2-(6A,7,10,10A-Tetrahydro-6,6,9-Trimethyl-1-Hydroxy-6H-Dibenzo [B,d]Pyranyl)-2-Hexyl-1,3-Dithiolane And Its Methylated Analog. Journal of Pharmaceutical and Biomedical Analysis 1999, 18, 947 - 956. Website
Mavromoustakos, T. ; Daliani, I. Effects Of Cannabinoids In Membrane Bilayers Containing Cholesterol. Biochimica et Biophysica Acta - Biomembranes 1999, 1420, 252 - 265. Website
Kolocouris, A. ; Tataridis, D. ; Fytas, G. ; Mavromoustakos, T. ; Foscolos, G. B. ; Kolocouris, N. ; De Clercq, E. Synthesis Of 2-(2-Adamantyl)Piperidines And Structure Anti-Influenza Virus A Activity Relationship Study Using A Combination Of Nmr Spectroscopy And Molecular Modeling. Bioorganic and Medicinal Chemistry Letters 1999, 9, 3465 - 3470. Website
1998
Matsoukas, J. M. ; Keramida, M. ; Panagiotopoulos, D. ; Mavromoustakos, T. ; Maia, H. L. S. ; Bigam, G. ; Pati, D. ; Habibi, H. R. ; Moore, G. J. Structure Elucidation And Conformational Analysis Of Gonadotropin Releasing Hormone And Its Novel Synthetic Analogue [Tyr(Ome)5, D-Lys6, Aze9Nhet]Gnrh: The Importance Of Aromatic Clustering In The Receptor Binding Activity. European Journal of Medicinal Chemistry 1998, 32, 927 - 940. Website
Mavromoustakos, T. ; Theodoropoulou, E. A Combined Use Of 13C-Cross Polarization/magic Angle Spinning, 13C-Magic Angle Spinning And 31P-Nuclear Magnetic Resonance Spectroscopy With Differential Scanning Calorimetry To Study Cannabinoid-Membrane Interactions. Chemistry and Physics of Lipids 1998, 92, 37 - 52. Website
Alexopoulos, K. ; Matsoukas, J. ; Tselios, T. ; Roumelioti, P. ; Mavromoustakos, T. ; Holada, K. A Comparative Sar Study Of Thrombin Receptor Derived Non Peptide Mimetics: Importance Of Phenyl/guanidino Proximity For Activity. Amino Acids 1998, 15, 211 - 220. Website
Mavromoustakos, T. Drug-Membrane Interactions An Example With The Pair Of Anesthetic Steroids Alphaxalone And Δ16-Alphaxalone. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1998, 12, 15 - 22. Website
Mavromoustakos, T. ; Stamos, I. K. ; Kamoutsis, C. ; Theodoropoulou, E. ; Zervou, M. ; Humpfer, E. Nuclear Magnetic Resonance Spectral Analysis And Conformational Properties Of 11-Benzoyl-9,9A,10,11-Tetrahydro-4H-Indolo[4,3-Ab]Carbazole. Journal of Pharmaceutical and Biomedical Analysis 1998, 16, 723 - 732. Website
Mavromoustakos, T. ; Zervou, M. ; Panagiotopoulos, D. ; Theodoropoulou, E. ; Matsoukas, J. ; Karussis, D. Structural Elucidation And Conformational Properties Of The Immunomodulator Linomide. Journal of Pharmaceutical and Biomedical Analysis 1998, 16, 741 - 751. Website
Mavromoustakos, T. ; Papadopoulos, A. ; Theodoropoulou, E. ; Dimitriou, C. ; Antoniadou -Vyza, E. Thermal Properties Of Adamantanol Derivatives And Their Β-Cyclodextrin Complexes In Phosphatidylcholine Bilayers. Life Sciences 1998, 62, 1901 - 1910. Website
1997
Mavromoustakos, T. ; Zervou, M. ; Theodoropoulou, E. ; Panagiotopoulos, D. ; Bonas, G. ; Day, M. ; Helmis, A. 13C Nmr Analysis Of The Triacylglycerol Composition Of Greek Virgin Olive Oils. Magnetic Resonance in Chemistry 1997, 35, S3 - S7. Website
Matsoukas, J. ; Hollenberg, M. D. ; Mavromoustakos, T. ; Panagiotopoulos, D. ; Alexopoulos, K. ; Yamdagni, R. ; Wu, Q. ; Moore, G. J. Conformational Analysis Of The Thrombin Receptor Agonist Peptides Sfllr And Sfllr-Nh2 By Nmr: Evidence For A Cyclic Bioactive Conformation. Journal of Protein Chemistry 1997, 16, 113 - 131. Website
Matsoukas, J. ; Hollenberg, M. D. ; Mavromoustakos, T. ; Panagiotopoulos, D. ; Alexopoulos, K. ; Yamdagni, R. ; Wu, Q. ; Moore, G. J. Conformational Analysis Of The Thrombin Receptor Agonist Peptides Sfllr And Sfllr-Nh2 By Nmr: Evidence For A Cyclic Bioactive Conformation. Protein Journal 1997, 16, 113 - 131. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Zervou, M. ; Karussis, D. ; Matsoukas, J. Conformational Properties Of The Immunomodulator Linomide. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1997, 11, 70 - 74. Website
Matsoukas, J. M. ; Alexopoulos, K. ; Tselios, T. ; Roumelioti, P. ; Yamdagni, R. ; Wu, Q. ; Mavromoustakos, T. ; Kalatzis, E. ; Siapi, E. ; Moore, G. J. Differences In Backbone Structure Between The Super Agonist [Sar1] Angiotensin Ii And Its Type I Antagonist Sarilesin. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1997, 11, 132 - 136. Website
Panagiotopoulos, D. ; Alexopoulos, K. ; Matsoukas, J. M. ; Mavromoustakos, T. ; Theodoropoulou, E. ; Kalatzis, E. ; Fatseas, P. ; Saifeddine, M. ; Hollenberg, M. D. Synthesis And Activities Of Cyclic Thrombin Receptor-Derived Peptide Analogues Of The Ser42-Phe-Leu-Leu-Arg46 Motif Sequence, Containing 2,3- Diamino-Propionic Acid. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1997, 11, 128 - 131. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Yang, D. - P. The Use Of High-Resolution Solid-State Nmr Spectroscopy And Differential Scanning Calorimetry To Study Interactions Of Anaesthetic Steroids With Membrane. Biochimica et Biophysica Acta - Biomembranes 1997, 1328, 65 - 73. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Alexopoulos, K. ; Matsoukas, J. ; Hollenberg, M. ; Moore, G. J. Use Of Molecular Modeling To Study Superimposition Of The Thrombin Receptor Motif S42Fllr46 With Its Peptidomimetic Analogs. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1997, 11, 125 - 127. Website
1996
Antoniadou -Vyza, E. ; Tsitsa, P. ; Theodoropoulou, E. ; Mavromoustakos, T. Complexation Of New Active Antibacterial Adamantan Derivatives With Β Cd: Preparation And Characterization Of Complexes Study Of The Thermotropic Properties Of Pure And Complex Form With Dipalmitoyl Phosphatidylcholine Bilayers. Journal of Inclusion Phenomena and Molecular Recognition in Chemistry 1996, 25, 161 - 164. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Yang, D. P. ; Lin, S. Y. ; Koufaki, M. ; Makriyannis, A. The Conformational Properties Of The Antineoplastic Ether Lipid 1 -Thiohexadecyl-2-O-Methyl-S-Glycero-3-Phosphocholine. Chemistry and Physics of Lipids 1996, 84, 21 - 34. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Dimitriou, C. ; Matsoukas, J. M. ; Panagiotopoulos, D. ; Makriyannis, A. Interactions Of Angiotensin Ii With Membranes Using A Combination Of Differential Scanning Calorimetry And 31P Nmr Spectroscopy. Letters in Peptide Science 1996, 3, 175 - 180. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Papahatjis, D. ; Kourouli, T. ; Yang, D. - P. ; Trumbore, M. ; Makriyannis, A. Studies On The Thermotropic Effects Of Cannabinoids On Phosphatidylcholine Bilayers Using Differential Scanning Calorimetry And Small Angle X-Ray Diffraction. Biochimica et Biophysica Acta - Biomembranes 1996, 1281, 235 - 244. Website
Theodoropoulou, E. ; Mavromoustakos, T. ; Panagiotopoulos, D. ; Matsoukas, J. M. ; Smith, J. Superimposition Of Potent Non-Peptide At1 Receptor Antagonists With Angiotensin Ii. Letters in Peptide Science 1996, 3, 209 - 216. Website
Panagiotopoulos, D. ; Matsoukas, J. M. ; Alexopoulos, K. ; Zebeki, A. ; Mavromoustakos, T. ; Saifeddine, M. ; Hollenberg, M. D. Synthesis And Activities Of Cyclic Thrombin-Receptor-Derived Peptide Analogues Of The Ser42-Phe-Leu-Leu-Arg46 Motif Sequence Containing D-Phe And/or D-Arg. Letters in Peptide Science 1996, 3, 233 - 240. Website
Matsoukas, J. M. ; Panagiotopoulos, D. ; Keramida, M. ; Mavromoustakos, T. ; Yamdagni, R. ; Wu, Q. ; Moore, G. J. ; Saifeddine, M. ; Hollenberg, M. D. Synthesis And Contractile Activities Of Cyclic Thrombin Receptor- Derived Peptide Analogues With A Phe-Leu-Leu-Arg Motif: Importance Of The Phe/arg Relative Conformation And The Primary Amino Group For Activity. Journal of Medicinal Chemistry 1996, 39, 3585 - 3591. Website
Koufaki, M. ; Calogeropoulou, T. ; Mavromoustakos, T. ; Theodoropoulou, E. ; Tsotinis, A. ; Makriyannis, A. Synthesis Of 2H-Labeled Alkoxyethyl Phosphodiester (Azt) Derivatives For Solid-State 2H-Nmr Studies. Journal of Heterocyclic Chemistry 1996, 33, 619 - 622. Website
Mavromoustakos, T. ; Yang, D. - P. ; Makriyannis, A. Topography And Thermotropic Properties Of Cannabinoids In Brain Sphingomyelin Bilayers. Life Sciences 1996, 59, 1969 - 1979. Website
Theodoropoulou, E. ; Mavromoustakos, T. ; Byza, A. Use Of Dsc To Study The Thermotropic Properties Of Octyl-, Decyl-, And Dodecyl-Bromine Salts Of Quaternary Dimethylamino-Adamantanol In Pure Or Complex Form With Β-Cyclodextrin In Dppc Bilayers. Epitheorese Klinikes Farmakologias kai Farmakokinetikes 1996, 14, 113 - 119. Website
Ioannou, A. ; Dimirkou, A. ; Mavromoustakos, T. Isotherms Of Phosphate Sorption By Hematite And Bentonite-Hematite (B-H) System. Communications in Soil Science and Plant Analysis 1996, 27, 1901 - 1924. Website
1995
Matsoukas, J. M. ; Agelis, G. ; Wahhab, A. ; Hondrelis, J. ; Panagiotopoulos, D. ; Yamdagni, R. ; Wu, Q. ; Mavromoustakos, T. ; Maia, H. L. S. ; Ganter, R. ; et al. Differences In Backbone Structure Between Angiotensin Ii Agonists And Type I Antagonists. Journal of Medicinal Chemistry 1995, 38, 4660 - 4669. Website
Mavromoustakos, T. ; Yang, D. - P. ; Makriyannis, A. Effects Of The Anesthetic Steroid Alphaxalone And Its Inactive Δ16-Analog On The Thermotropic Properties Of Membrane Bilayers. A Model For Membrane Perturbation. BBA - Biomembranes 1995, 1239, 257 - 264. Website
Mavromoustakos, T. ; Papahatjis, D. ; Kourouli, T. ; Theodoropoulou, E. ; Makriyannis, A. Recent Advances In The Field Of Cannabinoids: Synthesis Of Novel Analogs And Their Interactions With Membranes. Epitheorese Klinikes Farmakologias kai Farmakokinetikes 1995, 13, 105 - 128. Website
Mavromoustakos, T. ; Yang, D. - P. ; Makriyannis, A. Small Angle X-Ray Diffraction And Differential Scanning Calorimetric Studies On O-Methyl-(-)-Δ8-Tetrahydrocannabinol And Its 5′ Iodinated Derivative In Membrane Bilayers. BBA - Biomembranes 1995, 1237, 183 - 188. Website
Mavromoustakos, T. ; Yang, D. P. ; Theodoropoulou, E. ; Makriyannis, A. Studies Of The Conformational Properties Of The Cannabimimetic Aminoalkylindole Pravadoline Using Nmr And Molecular Modeling. European Journal of Medicinal Chemistry 1995, 30, 227 - 234. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Polychroniou, V. ; Dimitriou, A. ; Koufaki, M. ; Calogeropoulou, T. Study Of Drug Membrane Interactions Using A Combination Of Differential Scanning Calorimetry And 31P-Nmr Spectroscopy. Epitheorese Klinikes Farmakologias kai Farmakokinetikes 1995, 13, 81 - 90. Website
Mavromoustakos, T. ; Yang, D. - P. ; Theodoropoulou, E. ; Makriyannis, A. Use Of Molecular Graphics As An Aid In The Study Of Conformational Properties Of Aminoalkylindole Pravadoline And The Analgesic Cannabinoid Cp-55,940. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1995, 9, 113 - 116. Website
1994
Matsoukas, J. M. ; Hondrelis, J. ; Keramida, M. ; Mavromoustakos, T. ; Makriyannis, A. ; Yamdagni, R. ; Wu, Q. ; Moore, G. J. Role Of The Nh2-Terminal Domain Of Angiotensin Ii (Ang Ii) And [Sar1]Angiotensin Ii On Conformation And Activity: Nmr Evidence For Aromatic Ring Clustering And Peptide Backbone Folding Compared With [Des-1,2,3]Angiotensin Ii. Journal of Biological Chemistry 1994, 269, 5303 - 5312. Website
Mavromoustakos, T. ; Yang, D. - P. ; Makriyannis, A. Topography Of Alphaxalone And Δ16-Alphaxalone In Membrane Bilayers Containing Cholesterol. BBA - Biomembranes 1994, 1194, 69 - 74. Website
Mavromoustakos, T. ; Theodoropoulou, E. ; Matsoukas, J. ; Moore, G. ; Smith, J. Use Of Molecular Modeling To Study Superimposition Of Angiotensin Ii With Its Non-Peptide Receptor Antagonists. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1994, 8, 137 - 142. Website
1993
Mavromoustakos, T. ; Theodoropoulou, E. ; Koufaki, M. ; Yang, D. - P. ; Lin, S. ; Zervou, M. ; Kalogeropoulou, T. ; Makriyannis, A. Conformational Analysis Of 1-Thiohexadecyl-2-O-Methyl-Rac-Glycero-3-Phosphocholine. Epitheorese Klinikes Farmakologias kai Farmakokinetikes 1993, 11, 178 - 187. Website
Yang, D. - P. ; Mavromoustakos, T. ; Makriyannis, A. Small Angle X-Ray Diffraction Studies Of (-)-Δ8-Tetrahydrocannabinol And Its O-Methyl Analog In Membranes. Life Sciences 1993, 53, PL117 - PL122. Website
Mavromoustakos, T. ; Makriyannis, A. Study Of The Thermotropic Properties Of Drug Molecules In Lipid Bilayers Using Differential Scanning Calorimetry (Dsc). Epitheorese Klinikes Farmakologias kai Farmakokinetikes 1993, 11, 13 - 21. Website
Martel, P. ; Makriyannis, A. ; Mavromoustakos, T. ; Kelly, K. ; Jeffrey, K. R. Topography Of Tetrahydrocannabinol In Model Membranes Using Neutron Diffraction. BBA - Biomembranes 1993, 1151, 51 - 58. Website
Mavromoustakos, T. ; Makriyannis, A. The Use Of Molecular Graphics As An Aid In The Study Of The Conformational Properties Of Biologically Active Molecules. Epitheorese Klinikes Farmakologias kai Farmakokinetikes 1993, 11, 88 - 99. Website
1992
Yang, D. - P. ; Mavromoustakos, T. ; Beshah, K. ; Makriyannis, A. Amphipathic Interactions Of Cannabinoids With Membranes. A Comparison Between Δ8-Thc And Its O-Methyl Analog Using Differential Scanning Calorimetry, X-Ray Diffraction And Solid State 2H-Nmr. BBA - Biomembranes 1992, 1103, 25 - 36. Website
Chester, D. W. ; Skita, V. ; Young, H. S. ; Mavromoustakos, T. ; Strittmatter, P. Bilayer Structure And Physical Dynamics Of The Cytochrome B5 Dimyristoylphosphatidylcholine Interaction. Biophysical Journal 1992, 61, 1224 - 1243. Website
1991
Makriyannis, A. ; Yang, D. P. ; Mavromoustakos, T. Combined Use Of Solid-State Nuclear Magnetic Resonance Spectroscopy, Small-Angle X-Ray Diffraction, And Differential Scanning Calorimetry In Studies Of Cannabinoid: Membrane Interactions. NIDA research monograph 1991, 112, 106 - 128. Website
Mavromoustakos, T. ; Yang, D. - P. ; Broderick, W. ; Fournier, D. ; Makriyannis, A. Small Angle X-Ray Diffraction Studies On The Topography Of Cannabinoids In Synaptic Plasma Membranes. Pharmacology, Biochemistry and Behavior 1991, 40, 547 - 552. Website
1990
Mavromoustakos, T. ; Yang, D. - P. ; Charalambous, A. ; Herbette, L. G. ; Makriyannis, A. Study Of The Topography Of Cannabinoids In Model Membranes Using X-Ray Diffraction. BBA - Biomembranes 1990, 1024, 336 - 344. Website
Makriyannis, A. ; Yang, D. P. ; Mavromoustakos, T. The Molecular Features Of Membrane Perturbation By Anaesthetic Steroids: A Study Using Differential Scanning Calorimetry, Small Angle X-Ray Diffraction And Solid State 2H Nmr. Ciba Foundation symposium 1990, 153, 172 - 184; discussion 185. Website
1989
Makriyannis, A. ; Mavromoustakos, T. Studies On Drug-Membrane Interactions Using Solid State Nmr, Small Angle X-Ray Diffraction And Differential Scanning Calorimetry. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 1989, 3, 95 - 114. Website
1988
Van der Schyf, C. J. ; Mavromoustakos, T. ; Makriyannis, A. The Conformation Of (-) 8 Α And (-) 8 Β-Hydroxy-Δ9-Tetrahydrocannabinols And Their Interactions With Model Membranes. Life Sciences 1988, 42, 2231 - 2239. Website